Meet SQUARNA 3.0, our tool for #RNA secondary structure prediction:
pypi.org/project/SQUA...
Now with options for @rfamdb.bsky.social Rfam template search and G-quadruplex pattern recognition!
Currently, as CLI and Python API, and soon, a web version.
#Rfam #G4 #Gquadruplex #Bioinformatics

DFT Analysis of Stacking Interactions and Cyclic H-Bond Cooperativity in G-Quadruplexes.
E, Soorya et al.
Paper
Details
#GQuadruplex #StackingInteractions #HydrogenBondCooperativity

RNA: Searching for druggable targets A strategy that analyzes the structural properties of RNA could help identify regions that are promising targets for antiviral drugs.

An editorial on our work publsihed in @elife.bsky.social
@ucllifesciences.bsky.social #GQuadruplex

I had a great time at #G4thering 2025 in Minneapolis earlier this month.
I gave a talk at the Young Scholar Forum and was awarded a travel grant by the G4 society - very grateful for the chance to present and connect with the G4 community!

#Gquadruplex #PhDLife #YoungScientist

Original post on scicomm.xyz

Today we will be hosting dr.Angelika Lahnsteiner from Salzburg University (Austria) for a talk titled:

#G-quadruplex|es are sites of differential methylation and alternative promoter usage in metabolic disorders and cancer

Please, visit https://bioinf.pages.fi.muni.cz/posts/iv106 for more […]

Exploring the modulation of the complex folding landscape of Human Telomeric DNA by low molecular weight ligands Telomeric DNA forms G-quadruplex (G4) structures. These G4s structures are crucial for genomic stability and therapeutic targeting. Using time-resolved NMR and CD spectroscopies, we investigated how ...

Check out our latest publication on DNA G-quadruplexes! We show how the ligand Phen-DC3 modulates the folding of the human telomeric repeat 23TAG DNA, providing insights into the modulation of G4 folding.

Read more here 👉 doi.org/10.1002/chem...

#DNA #GQuadruplex #folding #kinetics #realtime #NMR

Nuclear microRNA 9 mediates G-quadruplex formation and 3D genome organization during TGF-β-induced transcription - Nature Communications Three-dimensional genome organization is important for transcription regulation. Here the authors show that microRNA 9 mediates the formation of G-quadruplexes and the looping of promoters and super-e...

Study finds nuclear microRNA-9 drives G-quadruplex formation, impacting 3D genome structure during TGF-β-induced transcription, suggesting a role in enhancer-promoter loops. #Genome #Gquadruplex PMID:39706840, Nat Commun 2024, @NatureComms doi.org/10.1038/s414...

#research #Gquadruplex #DNA #NMR

NMR screen reveals the diverse structural landscape of a G-quadruplex library (Curtis) -
Chemistry – A European Journal : doi.org/10.1002/chem...

@iocbprague.bsky.social #CAS #CzechScience

Structural insights into G-quadruplex binding by metal co... G-quadruplex DNA secondary structures are formed in guani...

Just out - @PrietoTayler, @McquaidKane and I are honouring the pioneering nucleic acid structural work of Stephen Neidle with our review of G-quadruplex metal complex sructures. #G4 #openaccess #DNA #Gquadruplex #Xray #NMR link.springer.com/article/10.1007/s00044-0...

Mappati gli enigmatici nodi del Dna. Sono 50mila, potrebbero avere un ruolo contro tumori e infezioni. #DNAumano #gquadruplex #imotifs

Now at nearly 4000 views! Very pleased with this! #WomenInSTEM #DNA #Gquadruplex #ruthenium