#Immunity to #hemagglutinin and #neuraminidase results in additive reductions in #airborne #transmission of #influenza #H1N1 virus in #ferrets, etidiohnew.blogspot.com/2026/03/immu...
Identification of a Key #Hemagglutinin #Mutation Mediating #Antibody Escape in #Influenza #H1N1pdm09 Viruses,
etidiohnew.blogspot.com/2026/03/iden...
Stabilization of the #H5 clade 2.3.4.4b #hemagglutinin improves #vaccine-elicited neutralizing #antibody responses in mice, etidiohnew.blogspot.com/2026/03/stab...
Impact of an #aminoacid #deletion detected in the #hemagglutinin (HA) #antigenic site of swine #influenza A virus field strains on HA antigenicity, etidiohnew.blogspot.com/2026/02/impa...
Emergence and #antigenic characterisation of #influenza #H3N2 viruses with #hemagglutinin substitutions N158K and K189R during the 2024/25 influenza season, etidiohnew.blogspot.com/2026/02/emer...
- #Hemagglutinin (HA) is a major surface glycoprotein of influenza A virus, responsible for receptor binding and membrane fusion during viral entry. HA is initially synthesized as a precursor (HA0), which is cleaved into two subunits, HA1 & HA2, linked by a disulfide bond.
Researchers identify glucosidase alpha, neutral C (GANC) as a host factor in #H7N9; rare variants reduce #ViralReplication, while GANC knockdown limits #InfluenzaA via proteasome‑dependent #hemagglutinin degradation.
#OpenAccess in #STTT: doi.org/10.1038/s413...
www.youtube.com/watch?v=qEqY...
Novus Biologicals, Influenza A H5N1 Hemagglutinin Mouse anti-Influenza virus, Janelia Fluor 646, Clone: 2B7 @novusbiologicals.bsky.social #Influenza #h5n1 #Hemagglutinin #Janelia #Fluor
Structural basis for a potent #human neutralizing #antibody targeting a conserved epitope on the #H7 #hemagglutinin head, etidiohnew.blogspot.com/2025/11/stru...
Inverted #H1 #hemagglutinin nanoparticle #vaccines protect mice against challenges with human #H1N1 and bovine #H5N1 #influenza viruses, etidiohnew.blogspot.com/2025/11/inve...
Molecular divergence and #convergence of mammalian #antibody responses to the #influenza virus #hemagglutinin stem, etidiohnew.blogspot.com/2025/10/mole...
Impact of naturally occurring #hemagglutinin substitutions on antigenicity and fitness of #influenza #H5N1 virus, etidiohnew.blogspot.com/2025/10/impa...
Researchers show that GANC promotes #H7N9 virus replication by inhibiting proteasome-dependent #hemagglutinin (HA) degradation through reduced HA binding to PSMD1 and #PSMD2, linking GANC to viral susceptibility. #medsky
#STTT #OpenAccess: doi.org/10.1038/s413...
The #hemagglutinin proteins of clades 1 and 2.3.4.4b #H5N1 highly pathogenic avian #influenza viruses exhibit comparable attachment patterns to avian and #mammalian #tissues, etidiohnew.blogspot.com/2025/09/the-...
Ciliated cells promote high infectious potential of #influenza A virus through the efficient intracellular activation of #hemagglutinin, etidiohnew.blogspot.com/2025/08/cili...
Stabilization of #H5 highly pathogenic avian #influenza #hemagglutinin improves #vaccine-elicited neutralizing #antibody responses, etidiohnew.blogspot.com/2025/08/stab...
Detection of #Hemagglutinin #H5 #Influenza A Virus #RNA and Model of Potential Inputs in an Urban #California #Sewershed, etidiohnew.blogspot.com/2025/07/dete...
Random #mutagenesis of #influenza #hemagglutinin identifies new sites which modulate its acid-stability and cleavability, etidiohnew.blogspot.com/2025/07/rand...
Structural and functional characterization of the #antigenicity of #influenza A virus #hemagglutinin subtype #H15, etidiohnew.blogspot.com/2025/07/stru...
Phylogenetic and #Mutation #Analysis of #Hemagglutinin Gene from Highly Pathogenic Avian #Influenza Virus #H5 Clade 2.3.4.4b in South #America, etidiohnew.blogspot.com/2025/06/phyl...
4/7 Scientists will hunt for antibodies from past infections, decode viral genetics, and study the hemagglutinin protein — the molecular key H5N1 uses to break into cells. Every sample tells a story of transmission and survival.
#ViralGenetics #Hemagglutinin
Chimeric #hemagglutinin and #M2 #mRNA #vaccine for broad #influenza subtype protection, etidiohnew.blogspot.com/2025/06/chim...
The #hemagglutinin proteins of clades 1 and 2.3.4.4b #H5N1 #HPAI viruses exhibit comparable attachment patterns to #avian and #mammalian tissues, etidiohnew.blogspot.com/2025/06/the-...
A G219A #hemagglutinin #substitution increases #pathogenicity and viral #replication of Eurasian avian-like #H1N1 swine #influenza viruses, etidiohnew.blogspot.com/2025/05/a-g2...
A protective and broadly binding #antibody class engages the #influenza virus #hemagglutinin head at its stem interface, etidiohnew.blogspot.com/2025/05/a-pr...
#Phylogenetic Analysis and Spread of HPAI #H5N1 in Middle Eastern Countries Based on #Hemagglutinin and #Neuraminidase Gene Sequences, etidiohnew.blogspot.com/2025/05/phyl...
#Influenza gets help from #gum #disease #bacteria ...
| #Staphylococcus | #microbes | #hemagglutinin | #Porphyromonas | #periodontal | Via @asbmb.bsky.social
Also last week in @science.org : @kanekiyom.bsky.social, Douglas Reed, Simon Barratt-Boyes, & colleagues show pre-exposure broadly neutralizing #antibody ( #bnAb ) #prophylaxis against a conserved supersite on #influenza #hemagglutinin (HA) stem protects #macaques against #H5N1 infection! #BirdFlu
A study finds that humans without known exposure to #birdflu have antibodies that can recognize H5-specific #hemagglutinin & neutralize highly pathogenic #H5N1 @sciimmunology.bsky.social
www.science.org/doi/10.1126/...
PDF
www.science.org/doi/epdf/10....
#Bird #flu:
'A single mutation in #bovine #influenza #H5N1 #hemagglutinin switches specificity to #human receptors'
www.science.org/doi/10.1126/...