We also had fun with a wide range of techniques from RNAscope and western blot on human DRG, to skin nerve-terminal fractionation, peptide arrays, CRISPR gene editing in cultured and in-vivo DRG.
All converging on one conclusion: FGFR3-autoantibodies bind FGFR3 to sensitize pain.
#CRISPR #HumanDRG

@tedpricethepainguy.bsky.social @utdpaincenter.bsky.social Great visit today from Dr. Ted Price! Thank you for wowing us with your team’s exciting data on human DRG tissue, very inspiring and insightful seminar! #painresearch #dorsalrootganglia #humanDRG #nyudental #nyuniversity #nyupainresearch

#preprint #collaboration #gabapentin #humanDRG #pain
New preprint out! So much love went into this work, good job team! 🥰 Pleased with this next progression on understanding gabapentin since my review on its abuse potential: doi.org/10.1016/j.ph.... 💪