Specific cortisol blockade in Cushing's syndrome Cushing's syndrome is most frequently seen in patients on exogenous glucocorticoids (ie, steroids) for immune-related conditions (eg, rheumatoid arthritis and asthma) and specific haematological cance...

Ashley Grossman comments on:
Specific cortisol blockade in #Cushing's syndrome thelancet.com/journals/lan...
#hypercortisolism #hypertension

#MedSky #EndoSky

Efficacy and safety of relacorilant for the treatment of patients with Cushing's syndrome (GRACE): a multicentre, phase 3, double-blind, placebo-controlled, randomised-withdrawal study Patients treated with relacorilant were more likely to maintain hypertension control compared with patients treated with placebo. The findings support consideration of relacorilant as a therapeutic op...

Patients with endogenous #hypercortisolism of various causes given #relacorilant during the randomised-withdrawal phase were 5·9 times more likely to maintain #hypertension response compared with those who received placebo thelancet.com/journals/lan...
#Cushing's syndrome

#MedSky #EndoSky

EndoBytes: Patient-Centered Approach to Hypercortisolism Screening and Care | Learn how to develop individualized, patient-centered treatment plans for monitoring hypercortisolism symptoms: https://bit.ly/49ZqV8i #endocrinology #hypercortisolism

Survival probabilities in patients with ectopic Cushing’s syndrome – a systematic review and a single-arm meta-analysis by Marta Piasecka

EJE Volume 192, Issue 6, June 2025
Open access article 👉 doi.org/10.1093/ejen...

#endocrinology #cushings #hypercortisolism

🔥#ADA2025 gamechanger!

🔶 Will Mifepristone Prove A #CATALYST For Change?

🎯 The #CATALYST trial is the next evolution in personalised #T2D care. We should consider screening for #hypercortisolism in those with difficult-to-control #T2D

Link in comments below 👇🏾

@pharmrj.pharmsky.app

Mifepristone Helped Control Diabetes in Those With Hypercortisolism But risk for hypokalemia should be proactively addressed, researcher says

#Mifepristone (Korlym) reduced HbA1c levels in patients with inadequately controlled #type2diabetes and #hypercortisolism, a randomized placebo-controlled trial showed. #ADA2025 www.medpagetoday.com/meetingcover...

Groundbreaking CATALYST Study Reveals Mifepristone's Efficacy for Type 2 Diabetes Control The CATALYST study demonstrates that mifepristone significantly improves blood glucose control in patients struggling with type 2 diabetes and hypercortisolism.

Groundbreaking CATALYST Study Reveals Mifepristone's Efficacy for Type 2 Diabetes Control #USA #Chicago #Type_2_Diabetes #Mifepristone #Hypercortisolism

Prevalence of Hypercortisolism in Difficult-to-Control Type 2 Diabetes OBJECTIVE. Despite the use of multiple glucose-lowering medications, glycemic targets are not met in a significant fraction of people with type 2 diabetes.

Hipercortisolismo se asocia con hiperglucemia en una cuarta parte de los individuos con diabetes tipo 2 controlada inadecuadamente a pesar de múltiples medicamentos #hypercortisolism #T2D diabetesjournals.org/care/article...

#Circadian clock disruption impairs #immune oscillation in chronic endogenous #hypercortisolism: a multi-level analysis from a multicentre clinical trial
www.thelancet.com/journals/ebi...