Using single-cell RNA-seq, Manabu Wakamatsu, Hideki Muramatsu et al. @en.nagoya-u.ac.jp show that rhG-CSF suppresses IFNγ signaling and promotes B-cell differentiation in reticular dysgenesis, with potential benefits before #HSCT. rupress.org/jhi/article/...
#immunodeficiencies
Your research on center stage at ESID 2026!
Only one month left to submit your abstract and showcase your work at ESID 2026!
🗓️ Deadline: 05 May 2026 at midnight CEST
👉 Submit here: https://bit.ly/3vaXQDO
#ESID2026 #Immunodeficiencies
Over 50% of complex cases need reclassification after review.
The ESID EHA SIOPE 2025 Symposium proves that when rare diseases overlap, teamwork is the only way to a cure.
🔗 Podcast link: bit.ly/3NqNiw2
🔗 Full Report: bit.ly/4lsT50x
#Interplay2025 #Immunodeficiencies #Hematology
Unmanipulated bone marrow infusion without conditioning can rescue RECQL4-/- severe combined immunodeficiency. New study from Alexandra Grier and colleagues @chopresearch.bsky.social: rupress.org/jhi/article/...
#ClinicalPhenotypes #immunodeficiencies #InbornErrorsOfImmunity #SCID #HSCT
Oncostatin M receptor deficiency as a novel candidate genetic cause of autosomal recessive hyper-IgE syndrome. New study from Sisse Andersen, Kristian Assing, Trine H. Mogensen and colleagues @au.dk: rupress.org/jhi/article/...
#InbornErrorsOfImmunity #immunodeficiencies #InfectiousDiseases
Andersen, Assing, Mogensen et al. @au.dk describe a patient with #asthma, pulmonary #aspergillosis, and elevated IgE homozygous for a deleterious variant in the oncostatin M receptor. rupress.org/jhi/article/...
#InbornErrorsOfImmunity #immunodeficiencies #InfectiousDiseases #PopulationGenetics
Inborn errors of immunity at school: How can we do better? New study from Laura Lopez-Seguer, Jacques G. Riviere, Pere Soler-Palacin and colleagues @vallhebron.com: rupress.org/jhi/article/...
#InbornErrorsOfImmunity #IEI #immunodeficiencies #RareDisease #Peds #Education
@esidsociety.bsky.social
Beyond survival: Multisystem long-term outcomes following #HSCT in chronic granulomatous disease. New study from Valentina Guarnieri, Reem Elfeky and colleagues @greatormondst.bsky.social: rupress.org/jhi/article/...
#InbornErrorsOfImmunity #immunodeficiencies #CGD
@esidsociety.bsky.social
In @jhumimmunity.org, Duintjer, Blom et al. @unileiden.bsky.social present clinical follow-up data of 6.5 years of #NewbornScreening for #SCID, underscoring the importance of preventing overtreatment and avoiding unnecessary prolonged follow-up. rupress.org/jhi/article/...
#Immunodeficiencies
Duintjer, Blom et al. @unileiden.bsky.social present clinical follow-up data of 6.5 years of #NewbornScreening for #SCID, underscoring the importance of preventing overtreatment and avoiding unnecessary prolonged follow-up. rupress.org/jhi/article/...
#Diagnostics #Immunodeficiencies
This is very impactful if we can further apply the findings in certain #monogenic #immunodeficiencies
@jhumimmunity.org's January Issue is here! rupress.org/jhi/issue/2/1
The cover image shows DNA methylation alterations in B cells in ICF syndrome and other primary #immunodeficiencies. From Martins-Ferreira and @eballestar.bsky.social: doi.org/10.70962/jhi...
JHI’s January Issue is here! rupress.org/jhi/issue/2/1
The cover image shows DNA methylation alterations in B cells in ICF syndrome and other primary #immunodeficiencies. From Martins-Ferreira and @eballestar.bsky.social: doi.org/10.70962/jhi...
Kedrion's Commitment to Innovation and Patient Care at IPIC 2025 #Italy #Castelvecchio_Pascoli #Kedrion #Immunodeficiencies #IPIC_2025
Kedrion Pioneers Discussion on Secondary Immunodeficiencies at IPIC 2025 #Italy #Kedrion_Biopharma #Castelvecchio_Pascoli #Immunodeficiencies #IPIC_2025
Kedrion Leads the Charge on Secondary Immunodeficiencies at IPIC 2025 #USA #Prague #Kedrion_Biopharma #Immunodeficiencies #IPIC_2025
Day 2 at the @EAPSCongress features a 👍 session on "Challenges in managing #immunodeficiencies" with talks on managing #PID #IEI in the ER by Dr Pere Soler-Palacin; Dr Fabien Touzot on diagnostic challenges of ALPIDs & on genetic susceptibility to infections by Dr Colobran Oriol
Minoxidil restores thymic growth in 22q11.2 deletion syndrome by limiting Sox9+ chondrocyte expansion. New study from Pratibha Bhalla, Nicolai van Oers and colleagues (The University of Texas Southwestern Medical Center): rupress.org/jhi/article/...
#immunodeficiencies #InbornErrorsOfImmunity
Improved outcome of #HSCT in #STAT1 gain-of-function disease following JAK inhibition bridging. A new report from Emilie Pauline Buddingh, Catharina Schuetz et al.
rupress.org/jhi/article/...
#Autoimmunity #InbornErrorsofImmunity #Immunodeficiencies #Therapeutics
📅 Save the Date: ESID 2026 is coming to Maastricht!
Join us 14–17 October 2026 for four days of learning, discovery & connection across immunology.
Theme: Translational Immunology Beyond Boundaries
More soon! 👇 esidmeeting.org #ESID2026 #Immunodeficiencies
Two different forms of inherited human TCR⍺ chain deficiency. New study from Marie Materna, Vivien Béziat (@vbeziat.bsky.social) and colleagues @institutimagine.bsky.social: rupress.org/jhi/article/...
#TCellDeficiencies #immunodeficiencies #InbornErrorsOfImmunity
Reminder: The abstract submission deadline for ESID EHA SIOPE 2025 is 10 June. If your research bridges #immunodeficiencies, #haematology, and #paediatriconcology, this is the perfect place to share it. Looking forward to seeing your work. invt.io/1bxbqki1yxh
#interplay2025
