Yes, HC diversity is higher ...why? Something to do with clonal expansion after infection, followed by a contraction phase? #Immunology101
Again, show those non-infected controls please. Show that you are not making stuff up.
...
"Wir brauchen Mikroben, um gesund zu sein, aber man muss nicht krank werden, um gesund zu sein! So funktioniert das nicht."
#Immunology101 #MedSly #ImmunoSkyEs
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Robert Koch and Louis Pasteur
There are many stories about “germ theory” and "hygiene hypothesis" based on unfortunate misunderstandings and simplifications.
We do need microbes to be healthy, but you don't have to get sick to be healthy! That's not how it works.
#Immunology101 #MedSly #ImmunoSky
This other mechanism is the ↘️ expression of MHC-1 on the surface of cells infected by SARS-CoV-2. A characteristic which differentiates it+++ from Influenza viruses which on the contrary tend to ↗️ this expression...
People without knowledge of basic immunology or virology keep claiming fantasy on social media platforms.
Detection of infection works via many different receptors. Immunity is complex. It has to be, otherwise we would get outmanoeuvred by microbes evolving.
#immunology101
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How many distinct effector immune responses are established against invading pathogens?
This was the question in a recent poll to get some insights into the level of knowledge present. What was the score? Many! No, that is not the correct answer.
#Immunology101
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For a new #immunology101 a short quiz (for non-immunologist).
How many distinct effector immune resposes are established against invading pathogens?
This combines innate and adaptive branches of immunity. Don't look it up! The answer and explanation will come mid week.
1, 2, 3 or many?
Discriminating self from non-self.
How is it possible that our immune system can detect such a wide variety of invaders? It also identifies the type of infection and determines the best action strategy! All this, without you doing anything conscientiously.
#Immunology101
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How come the adaptive immune response is slow?
The main cell types of the adaptive immune response, B and T cells do not have their antigen-specific receptor encoded in their DNA, but each cell makes a nearly unique one.
#Immunology101
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Antibodies and Antigens
An antigen is any substance recognized by the immune system. It can bind to detection receptors found on our cells. An antigen is not exclusively produced, it can be any component of anything, from the environment to even self.
#immunology101
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Antibodies and Antigens
White blood cells called B cells have many copies of 1 receptor that can bind to something that is not you. This receptor, an immunoglobulin, can be secreted at high amounts by B cells, this soluble protein is called an antibody
#immunology101
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Immunology is the study of host defence mechanisms
Immunity is the ability of the host to protect itself against Invasion (and more!)
The immune system comprises of tissues, cells and molecules which detect danger and mount the immune response
#Immunology101