This comprehensive #STTT overview delineates the molecular complexity, stem cell, and microenvironmental influences on #Glioblastoma progression and therapy resistance, highlighting emerging targeted and #Immunotherapeutic strategies.

#OpenAccess: doi.org/10.1038/s413...

This review examines the origin, functional diversity, and disease relevance of cytotoxic CD4+ T cells and discusses their emerging potential as #Immunotherapeutic targets in #Cancer, infectious, and #AutoimmuneDiseases.

#STTT #OpenAccess: doi.org/10.1038/s413...

Stanford Cancer Institute features advancements in immunotherapy cancer treatments In a Jan. 13th installation of the Stanford Cancer Institute’s “Breakthroughs in Cancer” lecture series, Lawrence Fong M.D.’92 discussed his lab’s research enhancing internal immune responses in patients. The post Stanford Cancer Institute features advancements in immunotherapy cancer treatments appeared first on The Stanford Daily.

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Tau hyperphosphorylation is a hallmark of #Alzheimers disease. Using StressMarq's #tau constructs, p5555kb, an #immunotherapeutic, was shown to effectively decrease tau pathology & aggregate buildup in mice.

Paper 📙 https://bit.ly/4pTgw4C
Products 🍊 https://bit.ly/3RKlyli

Schematic representation of nanovaccine approaches for NSCLC management. (a) siRNA-based gene silencing within tumor cells. (b) TME remodeling via immune activation approach to enhance tumor destruction.

This review summarizes advances in #cancer #nanovaccines, highlighting #nanocarriers, and innovations such as #immunotherapeutic nanovaccines, STING agonist vaccines, and #nanogels, emphasizing their potential to reduce cancer recurrence.
Nanotechnology Reviews: doi.org/10.1515/ntre...

Introducing N-deglycosylation targeting chimera (DGlyTAC), a novel technique for removing N-glycans from a target protein on the cell surface, demonstrating excellent target specificity and #immunotherapeutic ability. #medsky

#STTT #OpenAccess: doi.org/10.1038/s413...

The WIC #Symposium will be held on Wednesday, Nov. 5 at the 40th Annual Meeting & Pre-Conference Programs! The #WIC will bring together international investigators to highlight groundbreaking #immunotherapeutic advances across the globe! Register: sitcancer.org/2025/schedule/sitc25-preconference#wic

This review explores the intricate interplay between different components of the #ImmuneMicroenvironment and the associated mechanisms in the #pathogenesis of #ADPKD, and summarizes the currently available & potential #Immunotherapeutic approaches. #RenalDysfunction #medsky

buff.ly/yR6zEod

The link between intracellular calcium signaling and exosomal PD-L1 in cancer progression and immunotherapy

In this review, researchers at @universityofky.bsky.social discuss targeting calcium signaling to inhibit the release of PD-L1-containing #exosomes as a novel #AntiCancer therapeutic approach that could enhance the #immunotherapeutic response in patients. #medsky

www.sciencedirect.co...

Targeting CD47-SIRPα axis for Hodgkin and non-Hodgkin lymphoma immunotherapy

This review describes targeting the CD47-SIRPα axis as a promising #immunotherapeutic strategy in the treatment of Hodgkin & non-#HodgkinLymphomas, and outlines the latest strategies for targeting this axis. #medsky

#OpenAccess: www.sciencedirect.co...