Tackling the challenge of γ-lactams with chiral α-quaternary carbons! This #Synpacts article by Mengchun Ye & co-workers highlights asymmetric ring decoration & TM-catalyzed carbonylative cyclization, plus future directions🚀
#lactams #catalysis

👉 buff.ly/PGx50Dq

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We report a modular flow cascade for the synthesis of γ- & N-substituted γ-lactams via photochemical radical alkylation and cyclization.

Fast, scalable & broad scope!

🔗 chemrxiv.org/engage/chemr...

#FlowChemistry #Photochemistry #Lactams