Light-Assisted Akamptisomerization: Excited-State Bond-Angle Reflection (ESBAR) as a Molecular Photoswitching Element in B2OF2–Porphyrins Akamptisomerism arises from bond-angle reflection (BAR) at a B–O–B bridge in low-symmetry B2OF2 porphyrins and leads to isolable diastereisomers in the ground state. Herein, we present the first theor...

Excited-state chemistry meets akamptisomerism! We show that akamptisomerism in B2OF2-porphyrins is easier in the triplet state: a new light-driven photoswitching pathway. Open-acess paper. #DFT #Photoswitch #ChemTwitter #Photochemistry

Inorganic Chemistry pubs.acs.org/doi/full/10....

Shining new light on #epoxides 🔬 Huang & co-workers unveil a visible-light-driven route to α-amino epoxides via an oxa-π,σ-methane rearrangement🧪 Mild, selective, and versatile—breaking past traditional synthetic limits
#photochemistry

👉 buff.ly/zwtp2cL

More than Meets the eye: the expanding horizon of photosciences - Photochemical & Photobiological Sciences Photochemical & Photobiological Sciences -

New editorial by our colleague @maxxtrotta.bsky.social and Sofia Costa, Publishing Editor of the Comprehensive Series in Photochemical and Photobiological Sciences (#SpringerNature)
👉 link.springer.com/article/10.1...
#photoscience
#photobiology
#photochemistry

Explore the full potential of #quinoxaline ✨ Patel & co-workers reveal sustainable strategies—bis-functionalization, #photochemistry ☀️, C3–H activation, spiro-etherification—for broad, scalable, green syntheses 🌱

👉 buff.ly/FrPAoOh

Who’s in Newcastle on Friday? 🖤 🤍

So looking forward to catching up with everyone at the @rsc.org’s Organic Chemistry North-East Meeting, @newcastleuni.bsky.social, & showcasing the latest Asynt product portfolio.

Howay, let’s do this! 😉

#Photochemistry #FlowChemistry #SustainableLabs

🧪 We're hiring a fully funded PhD @Durham Chemistry, synthesising organic semiconductor libraries for the next generation of quantum materials.
UK/home students.
🔗 www.findaphd.com/phds/project...

#PhD #Chemsky #Photochemistry

⚡Electrophotocatalysis for C(sp²)–H functionalization!

Graphical review by Jiusi Yang & Peng Qian on #photoelectrocatalytic C–H activation, merging light & electricity for selective functionalization of arenes, heteroarenes, #alkenes & imines

🔗 Read now: bit.ly/4799ul2
#ChemSky #Photochemistry

Enantiodivergent Evolution of a De Novo Protein for Enzymatic [2 + 2] Photocycloaddition Activity The design of artificial photoenzymes by incorporating synthetic chromophores into proteins represents a promising strategy to achieve non-natural biocatalytic transformations with high levels of ster...

Excited to share our newest ACS Catalysis paper @pubs.acs.org from Benny, jointly from our lab and @cathleenzeymer.bsky.social on the enantiodivergent evolution of a de novo protein for [2+2] photocycloadditions! 💡🙌
#photochemistry #photoenzyme #biocatalysis 💡🙌

Don't miss your chance to sign up for a fantastic conference with a great lineup! You still have a chance until 15 April. Join us in Groningen

#ISOP2026 #photochemistry

Poster for 11th interantional symposium of photochromism hosted by Ben Feringa and colleagues in Groningen in July. There is a picture of the quite large model of a nanocar in front of the academic building in Groningen and text stating call for abstracts deadline extended.

Almost Final call for oral abstracts for ISOP 2026!
Join us in Groningen on 6–9 July for four days of exciting photochromism, discussion and networking.
🌐 isop2026.eu

🗓 Oral abstracts will continue to be considered until 15 April

#ISOP2026 #Photochemistry #MolecularSwitches #ChemSky

Cambridge researchers develop light-driven reaction to efficiently modify drug molecules Scientists from the University of Cambridge have discovered a light-powered chemical reaction that could revolutionize how drugs are developed and modified. The unexpected finding, published in Nature Synthesis, introduces an 'anti-Friedel–Crafts' reaction that allows chemists to make precise changes to complex drug molecules late in the development process. Unlike conventional Friedel–Crafts chemistry, which depends on toxic reagents, heavy metals, and harsh conditions, this new method uses a simple LED lamp to trigger carbon–carbon bond formation under mild, eco-friendly conditions. The durable and selective reaction enables scientists to adjust one part of a molecule while leaving others unchanged, cutting down synthesis steps, time, cost, and environmental impact. This makes it ideal for late-stage optimization, where small structural tweaks can improve drug performance or reduce side effects. The discovery emerged accidentally when PhD researcher David Vahey removed a photocatalyst during a control experiment and found the reaction worked even better without it. Realizing the potential, the team explored the mechanism further with help from AI models developed alongside Trinity College Dublin. These machine learning tools predicted how the reaction would behave with entirely new molecules, significantly reducing trial-and-error experimentation. Led by Professor Erwin Reisner, known for research inspired by photosynthesis, the team collaborated with AstraZeneca to assess industrial scalability and sustainability. The breakthrough not only enhances medicinal chemistry but also exemplifies how scientific serendipity—turning a failed experiment into a major advance—continues to drive innovation.

Cambridge researchers develop light-driven reaction to efficiently modify drug molecules

🤖 IA: It's not clickbait ✅
👥 Usuarios: It's not clickbait ✅

#chemistry #drugdevelopment #photochemistry

View full AI summary:

Interested in Photochemistry in Flow?

Make lab life that little bit easier with the Borealis from AsyntFlow.

💡 Standard wavelength options: 365 nm, 385 nm, 405 nm, 420 nm, 455 nm and 525 nm

🔗 www.asynt.com/product/bore...

#Photochemistry #FlowChemistry #AsyntFlow

📣 Swiss Photochemistry Symposium 2026
🗓️ 12. June, 2026 - @HEIA Fribourg
Register and submit your abstract for a contributed talk until March 15 ➡️ photochem26.scg.ch/registration
#photochem26 #scs #chemistry #photochemistry #switzerland #symposia

Bonjour Forum Labo! 🐼 💚🧪

We’re ready to rock and roll on the CLOUP Ateliers booth - D14.

Another fantastic stand design from Muriel Cugnasca and company.

Take a leaf out of nature’s book. The best chemistry grows on the green side.

#Asynt #GreenChemistry #Photochemistry

Asynt’s brand new #Photoreactor brochure has landed.

If you are exploring #photoredox, scaling light driven reactions or simply looking for more control over your irradiations, check this out:

asynt.com/wp-content/upl…

Ready to brighten up your chemistry?

#photochemistry #photocatalysis

Dearomatization of Aromatic Carbonyl Compounds by Photocycloaddition Reactions to 1,1-Dimethylallene The photocycloaddition of 1,1-dimethylallene to various aromatic carbonyl compounds was found to occur exclusively at the benzene core. While the reaction with methyl 2-methoxybenzoate resulted in a mixture of products resulting from ortho, meta, and para photocycloaddition, acetophenone and its 4-substituted derivatives delivered the respective para photocycloaddition products in 50–58% yields. For 2-methoxyacetophenone, an ortho photocycloaddition initiated a reaction cascade, which led to bicyclic products by the incorporation of a nucleophile in 29–74% yields.

Our new paper on the dearomatization of aromatic carbonyl compounds by photocycloaddition is out now in Organic Letters @pubs.acs.org Congratulations, Luis, for your excellent work 💡🙌💫 #photochemistry pubs.acs.org/doi/10.1021/...

💡 Visible light unlocking #heterocycles!

Eosin Y–catalyzed reductive cyclization of N/O-aryl bisenones affords functionalized pyrrolidines & THFs, exclusive trans #isomers & enantioenriched products!

🔗 Read the full paper: bit.ly/4tXrvwj
#ChemSky #Photochemistry #OrganicChemistry

Yu Zhao & Jun Xuan review how visible-light #photochemistry drives S–N bond cleavage to difunctionalize alkenes & alkynes, unlocking efficient routes to bioactive sulfur–nitrogen motifs💡
#radicals

👉 buff.ly/XSJznV0

It was a pleasure to be at #CIQSO last week for a seminar and Jialei Chen Wu #PhDdefense 🎓

Many thanks for the kind invitation and warm welcome! I truly enjoyed learning more about your amazing work and exchanging ideas with the #Organic #Synthesis and #Photochemistry Lab.

Photochemical Cyclization of Tertiary Buta‐2,3‐dienamides to β‐Lactams Upon Triplet Energy Transfer Energy transfer is the key to the successful photocyclization of the title compounds to 3,4-disubstituted 2-azetidinones. If the substituent at the nitrogen atom is primary (R2 = H), trans products a...

We're very proud to announce our newest publications on the photochemical cyclization of tertiary buta-2,3-dienamides to β-lactams! A big thanks to the collaborators from the Kerzig Group (@ckerzig.bsky.social) @angewandtechemie.bsky.social #photochemistry 💡🙌🧑‍🔬
onlinelibrary.wiley.com/doi/10.1002/...

Sygnature Discovery, a leading contract research organisation supporting #drugdiscovery programmes worldwide, is using Asynt’s #photoreactor range to enhance #photocatalytic reaction development & optimisation.

🎥 www.youtube.com/watch?v=5yLt...

🔗 www.sygnaturediscovery.com

#Photochemistry

We're very happy to welcome our new Postdoc Dr. Rachel Cantrell! We wish you best of luck for your research 🌟💡👩‍🔬 #photochemistry #WomeninSTEM

High-quality LED solar simulators remove the uncertainties associated with using an unreliable light source. The yield: accurate results and reproducibility. #Chemistry, #Catalysis, #Photochemistry, #EngineeredSunlight
g2voptics.com/photochemist...

#NewTeamMembers! Happy to welcome Julia Hierholzer, Dilara Güler, Marcus Kraus and Shipeng Song to our research team!!🎉🎉 We’re thrilled to have them on board. Welcome, Julia, Dilara, Marcus, and Shipeng!! 👩‍🔬🧑‍🔬

#chemistry #photochemistry #electrochemistry #dominoreactions #onepotreactions #PROTACs

Matthew Hopkinson and co-researchers from Newcastle University and Freie Universität Berlin @freieuniversitaet.bsky.social developed light-driven methodologies for the reduction of #acylazolium salts using benzoylimidazolium triflate.

➡️ tinyurl.com/3hh6c7c7

#photochemistry #BJOC 💎🔓

The Lighthouse #photoreactor module, from Asynt, expands the Integrity 10 platform, helping labs run more controlled, high-throughput #photochemistry with greater confidence and reproducibility.

Many thanks to Chemical Industry Journal

🔗 lnkd.in/ekM2kTeQ

#screening #optimisation

Better light. Better chemistry. Better results. #Chemistry, #Catalysis, #Photochemistry, #EngineeredSunlight
g2voptics.com/photochemist...

Searching for bright ideas?💡

#GoogleIt #Photoreactors #Photochemistry @asynt.bsky.social

Photochemical Deracemization of Chromanes and its Application to the Synthesis of Enantiopure Bioactive Compounds Various substituted chromane-2-carboxamides were successfully deracemized by employing a chiral benzophenone (BP, 10 mol%) as photocatalyst and an achiral thiol as additive (20 mol%). The method was ...

Check out our newest publication on the photochemical deracemization of chromanes! Amazing work @bikig6.bsky.social Out now in @angewandtechemie.bsky.social 💡🌟 #photochemistry #deracemization
doi.org/10.1002/anie...

Hello Nottingham! 👋🏼

First exhibition of 2026 showcasing Asynt’s product portfolio at the @rsc.org’s “Chemistry Teaching in Practice” event

Let’s chat how we can help introduce #FlowChemistry, #Photochemistry, #Electrochemistry practices into teaching labs, in a cost efficient manner.