#ICYMI:
“The insights of [#LaskerAward winners] Görlich & McKnight are being harnessed in medical research.” --Tanja Mittag on how low-complexity domains of proteins impact human health 🧪
#Lasker2025 #phaseseparation #biophysics
MPI for Multidisciplinary Sciences
NEJM.org
https://ow.ly/Fbmy50XUcWn
📖 Looking for some weekend reading?
#ICYMI -- #Lasker jury members write in Proceedings of the National Academy of Sciences about the history and significance of the 2025 #LaskerAward winners' work. #Lasker2025 🧪
https://ow.ly/v7oB50WWkgX
#ICYMI:
"This advance fulfills a dream of scientists and families—the conversion of a fatal disease into a treatable one.” Jeffrey Friedman writes about the Clinical #LaskerAward in Proceedings of the National Academy of Sciences
#cysticfibrosis #Lasker2025 🧪
https://ow.ly/wke250XL6IY
“The work of McKnight and Görlich is a testament to curiosity-driven research.”
#ICYMI: William G. Kaelin Jr writes about this year’s Basic Research #LaskerAward winners in the @pnas.org #Lasker2025 collection. 🧪
www.pnas.org/doi/10.1073/...
@mpi-nat.bsky.social
#phaseseparation #biophysics
#DYK that #LaskerAward winner Lucy Shapiro was an artist before she earned her PhD? She went on to make seminal discoveries in genetics and founded Stanford’s #DevBio department. #Lasker2025 🧪
#LaskerAward winners Michael J. Welsh, Jesús (Tito) González, and Paul A. Negulescu developed a triple-drug combination treatment for #cysticfibrosis. Their work transformed a lethal disease into a manageable condition. #Lasker2025 🧪
www.youtube.com/watch?v=UM-8...
Why are low-complexity domains (LCDs) in proteins important?
#LaskerAward winners Dirk Görlich & Steven McKnight showed that they are critical for intracellular transport and organization. #Lasker2025 🧪
#structuralbiology #phaseseparation
@mpi-nat.bsky.social
Impossible vs. Unpreprecedented—2025 #LaskerAward winner Paul Negulescu on fixing the CFTR protein, not the gene: "It was regarded as impossible because it had never been done before, but actually, it was just unprecedented—and we often confuse the two." 🧪
#Lasker2025 #LaskerLaureate
“The Enigma of Protein Domains of Low-Sequence Complexity”
#LaskerAward winner S. McKnight writes about “these ugly duckling proteins” that turned out to be vital for cellular function. 🧪
#RNAbiology #phaseseparation #Lasker2025 #UTSWMedicalCenter #JAMA
ow.ly/klVz50WY5Hf
“In a remarkable convergence of a pressing therapeutic need and highly specialized technology,” #LaskerAward winners Negulescu & González #VertexPharmaceuticals "fashioned a personalized approach to therapeutic development.” #cysticfibrosis #Lasker2025 🧪
#LaskerAward winners Michael Welsh, Jesús (Tito) González, and Paul Negulescu developed a triple-drug combination treatment for #cysticfibrosis. Their work transformed a lethal disease into a manageable condition. #Lasker2025 #UniversityofIowa #VertexPharmaceuticals 🧪
“My life in science has been a gift that has allowed me to explore the chemical logic of a living cell while also remaining keenly aware of the state of global health.”—#LaskerAward winner Lucy Shapiro 🧪
#Lasker2025 #systemsbiology #StanfordMed #JAMA
ow.ly/V1f250WYQsM
PNAS Celebrates the 2025 Lasker Awards
Meet the 2025 #LaskerAward recipients, recognized for their groundbreaking contributions to science and medicine. In partnership with Albert and Mary Lasker Foundation, PNAS highlights this year’s honored research. Explore the collection: https://ow.ly/uZYe50X6eS9
#Lasker2025
PNAS Celebrates the 2025 Lasker Awards
Congratulations to the 2025 #LaskerAward winners! 🎉 Honorees: Dirk Görlich, Steve McKnight, Michael Welsh, Jesús (Tito) Gonzalez, Paul Negulescu & Lucy Shapiro. Discover their groundbreaking work in @pnas.org: www.pnas.org/post/update/...
#Lasker2025 #LaskerLaureate @laskerfdn.bsky.social
2025 Lasker Awards – “From simplicity to complexity: A path to innovation in science and art.” Read the essay in a PNAS Perspective. Portrait of Joseph L. Goldstein.
For 25 years, the Chair of the @laskerfdn.bsky.social Jury has reflected on science and art in an annual essay. This year, Joseph L. Goldstein explores “From simplicity to complexity: A path to innovation.” Read the PNAS Perspective: www.pnas.org/doi/10.1073/...
#Lasker2025 #LaskerLaureate
“The pioneering accomplishments of this year’s #LaskerAward recipients give us every reason to believe that the best is yet to come.” —@NEJM highlights the work that led to life-saving treatments for #cysticfibrosis. 🧪
#Lasker2025
How can parts of proteins that are thought to be structureless control organization and transport within a cell?
That’s exactly what #LaskerAward winners Steven McKnight and Dirk Görlich figured out. 🧪
@mpi-nat.bsky.social
#biophysics #RNAbiology #Lasker2025
📖 ow.ly/ZMRo50X0Cnz
📺 ow.ly/Ov9W50X0Cny
“Her ability to identify talent, foster collaboration, & build lasting institutional frameworks has left an indelible mark on each organization she has led.”
@leslievosshall.bsky.social on #LaskerAward winner Lucy Shapiro 🧪
#Lasker2025 @PNAS.org
2025 Lasker Awards – Lasker~Koshland Special Achievement Award in Medical Science. Read about her award-winning work! Portrait of Lucy Shapiro.
Lucy Shapiro receives the 2025 Lasker~Koshland Special Achievement Award for uncovering how bacteria coordinate genetic programs to form distinct daughter cells. Explore her career in biomedical science @pnas.org: www.pnas.org/doi/10.1073/...
#Lasker2025 #LaskerLaureate @laskerfdn.bsky.social
“In a remarkable convergence of a pressing therapeutic need and highly specialized technology,” #LaskerAward winners Negulescu & González "fashioned a personalized approach to therapeutic development.”
@nejm.org #cysticfibrosis #Lasker2025
ow.ly/JIRF50X0Cm5
2025 Lasker Awards – Lasker~DeBakey Clinical Medical Research Award Winners. Read about their award-winning work! Portraits of Jesús (Tito) Gonzalez, Michael Welsh, and Paul Negulescu
The 2025 Lasker~DeBakey Clinical Medical Research Award honors Michael Welsh, Jesús Gonzalez, and Paul Negulescu for breakthroughs in cystic fibrosis treatment. Explore their work in @pnas.org: www.pnas.org/doi/10.1073/...
#Lasker2025 #LaskerLaureate @laskerfdn.bsky.social
#ICYMI:
📺 Explainers of the #Lasker2025 Award winners and their work: laskerfoundation.org/the-2025-las...
#LaskerAward #LaskerLaureate #cysticfibrosis #devbio #phaseseparation #RNAbiology #biophysics #systemsbiology 🧪
Learn more about the 2025 #LaskerAward winners and their work:
📖 laskerfoundation.org/winners/2025...
📺 laskerfoundation.org/the-2025-las...
#devbio #phaseseparation #cysticfibrosis #Lasker2025 #LaskerLaureate #RNAbiology #systemsbiology 🧪
Lucy Shapiro was recognized with the 2025 #LaskerAward “for a 55-year career in biomedical science – honored for discovering how bacteria generate distinct daughter cells; and for exemplary leadership at the national level” 🧪
#Lasker2025 #devbio #systemsbiology
Michael J. Welsh, Jesús (Tito) González, and Paul A. Negulescu were recognized with the 2025 Clinical #LaskerAward “for their key roles in developing a novel treatment for #cysticfibrosis” 🧪
#Lasker2025 #LaskerLaureate
Görlich & McKnight were recognized with the 2025 Basic #LaskerAward “for discoveries that exposed the structures and functions of low-complexity domains within protein sequences” 🧪
@mpi-nat.bsky.social
#Lasker2025 #phaseseparation #RNAbiology
2025 Lasker Awards. Albert Lasker Basic Medical Research Award Winners. Dirk Görlich and Steve McKnight. Read about their award-winning work.
Dirk Görlich and Steve McKnight receive the 2025 Albert Lasker Basic Medical Research Award for uncovering how protein sequences govern intracellular transport and cellular organization. Read more @pnas.org: www.pnas.org/doi/10.1073/...
#Lasker2025 #LaskerLaureate @laskerfdn.bsky.social
Today we celebrate the 2025 #LaskerAward winners:
Dirk Görlich & Steven L. McKnight; Michael J. Welsh, Jesús (Tito) González, & Paul A. Negulescu; Lucy Shapiro
Congratulations to all! 🎉 🎉 🎉
#Lasker2025 #LaskerLaureate 🧪
@mpi-nat.bsky.social
