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Sometimes a liver biopsy is needed to understand what's happening inside your liver. But what does that involve? 🤔 Katie shares her first ever liver biopsy experience in her own words.
➡️ pscsupport.org.uk/psc-and-me/k... #PatientVoices #LiverBiopsy #PatientExperience #LetsBeatPSC

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New severity scores help non-invasively assess liver disease in pediatric GSD IX, while #liverbiopsy remains key for understanding fibrosis and guiding care. bit.ly/3VB0IpO #GIMO #GlycogenStorageDiseaseTypeIX #LiverDiseaseScoring #LiverFibrosis #LiverDiseaseSeverity

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Liver cancer is one of the fastest-growing cancers and a major contributor to cancer-related mortality. Minimally invasive, nonsurgical local liver therapies play a key role in appropriately selected patients with hepatobiliary cancer.

Magnetic resonance imaging (MRI) offers a compelling solution for liver interventions by providing multiplanar, real-time needle guidance without exposure to ionizing radiation. 
It has excellent soft tissue contrast, outstanding spatial and temporal resolution, and functional imaging capabilities like diffusion-weighted imaging. Additionally, real-time temperature measurement during liver ablation helps to ensure complete tumor destruction while preserving surrounding healthy tissue and thus minimizing collateral damage

The integration of MRI guidance into hepatobiliary cancer diagnosis and treatment marks a significant advancement in interventional oncology. Its unique qualities enhance precise and safe planning, execution and monitoring of liver biopsies, liver tumor ablation, and percutaneous biliary drainage. 

Shoutout and thank you to the coauthors: Marcel Gutberlet, Dominik Horstmann, Julian Glandorf, Bennet Hensen, Frank Wacker
Forschungscampus STIMULATE, Otto-von-Guericke Universität, Magdeburg, Germany / Department of Radiology, Hannover Medical School, Hannover, Germany

Liver cancer is one of the fastest-growing cancers and a major contributor to cancer-related mortality. Minimally invasive, nonsurgical local liver therapies play a key role in appropriately selected patients with hepatobiliary cancer. Magnetic resonance imaging (MRI) offers a compelling solution for liver interventions by providing multiplanar, real-time needle guidance without exposure to ionizing radiation. It has excellent soft tissue contrast, outstanding spatial and temporal resolution, and functional imaging capabilities like diffusion-weighted imaging. Additionally, real-time temperature measurement during liver ablation helps to ensure complete tumor destruction while preserving surrounding healthy tissue and thus minimizing collateral damage The integration of MRI guidance into hepatobiliary cancer diagnosis and treatment marks a significant advancement in interventional oncology. Its unique qualities enhance precise and safe planning, execution and monitoring of liver biopsies, liver tumor ablation, and percutaneous biliary drainage. Shoutout and thank you to the coauthors: Marcel Gutberlet, Dominik Horstmann, Julian Glandorf, Bennet Hensen, Frank Wacker Forschungscampus STIMULATE, Otto-von-Guericke Universität, Magdeburg, Germany / Department of Radiology, Hannover Medical School, Hannover, Germany

Interventional #MRI in the Liver: Why, When, and Where?
By Daniel Düx, MD; et al. ( @uni-magdeburg.de / Hannover Medical School, Germany).
🔗 marketing.webassets.siemens-healthineers.com/d67d220657dd...

#iMRI #interventionalRadiology #LiverBiopsy #MagnetomWorld #ImageGuidedTherapy #RadSky #MedSky

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Liver biopsy and thermal ablation of liver tumors are well-established procedures, typically performed under CT or ultrasound (US) guidance. However, small tumors are barely visible (especially on CT imaging), and unfavorable localizations for CT and US guidance (e.g., in the liver dome) increase the risk of sampling errors or incomplete ablation. For liver tumors < 3 cm in size, a sampling error of around 20% has been published. Furthermore, biopsy under CT guidance bears the risk of X-ray exposure, especially for the interventional radiologist. 

MRI provides a high soft tissue contrast that can even be enhanced for a prolonged period with hepatocyte-specific contrast agents. This enables better visualization of liver tumors than with CT or US imaging, where contrast enhancement is limited to a short period of time during the contrast agent administration. 

Furthermore, the slice orientation can be chosen freely in MRI. This allows a slice orientation along the needle trajectory, displaying needle and target within the slice regardless of the complexity of the angulation. 

MRI can be performed as fluoroscopic imaging with a fast frame rate of less than one second per image. Even an alternating display of the needle path in perpendicular projections is possible. 

As a consequence, small lesions and oblique needle access do not represent a limitation for biopsy or ablation under MRI guidance. With regard to liver biopsies, clinical success rates of around 90% for MRI-guided biopsies were described in some early studies, and, in some smaller case series, they were even higher (> 90%). 

Shoutout and thank you to the co-authors: Matthias Fabritius, M.D. and Jens Ricke, M.D.

Liver biopsy and thermal ablation of liver tumors are well-established procedures, typically performed under CT or ultrasound (US) guidance. However, small tumors are barely visible (especially on CT imaging), and unfavorable localizations for CT and US guidance (e.g., in the liver dome) increase the risk of sampling errors or incomplete ablation. For liver tumors < 3 cm in size, a sampling error of around 20% has been published. Furthermore, biopsy under CT guidance bears the risk of X-ray exposure, especially for the interventional radiologist. MRI provides a high soft tissue contrast that can even be enhanced for a prolonged period with hepatocyte-specific contrast agents. This enables better visualization of liver tumors than with CT or US imaging, where contrast enhancement is limited to a short period of time during the contrast agent administration. Furthermore, the slice orientation can be chosen freely in MRI. This allows a slice orientation along the needle trajectory, displaying needle and target within the slice regardless of the complexity of the angulation. MRI can be performed as fluoroscopic imaging with a fast frame rate of less than one second per image. Even an alternating display of the needle path in perpendicular projections is possible. As a consequence, small lesions and oblique needle access do not represent a limitation for biopsy or ablation under MRI guidance. With regard to liver biopsies, clinical success rates of around 90% for MRI-guided biopsies were described in some early studies, and, in some smaller case series, they were even higher (> 90%). Shoutout and thank you to the co-authors: Matthias Fabritius, M.D. and Jens Ricke, M.D.

MRI-Guided vs. CT-Guided Interventions: A Focus on the Liver by Max Seidensticker, M.D.; et al. (@lmuradiology.bsky.social, Munich, Germany).
🔗 marketing.webassets.siemens-healthineers.com/2f40dcbe0e82...

#MRI #InterventionalRadiology #LiverBiopsy #MRIguidedIntervention #RadSky #MagnetomWorld

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🎧Take a listen to this editorial focus in podcast format!

Got Guts: A Chance to Put Liver Biopsy Back to Its Former Glory?
🎙️ow.ly/1bjE50VhAyH
📃ow.ly/y0SP50VhAyF

#Cholangiocyte #DuctularReaction #Cholangiopathies #LiverBiopsy #MachineLearning

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Don’t miss out – register now! #BDIAP #Histopathology #LiverBiopsy #MedicalEducation

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Case 145: Transpancreatic Liver Lesion Biopsy
66-yrs old with a caudate lobe lesion and the approach
www.ctbiopsy.com/case145/
#ctbiopsy #irrad #liverbiopsy #caudatelobe #transpancreatic

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