Beyond the loss of beta cells: a quantitative analysis of islet architecture in adults with and without type 1 diabetes - Diabetologia Aims/hypothesis The organisation and cellular architecture of islets of Langerhans are critical to the physiological regulation of hormone secretion but it is debated whether human islets adhere to th...

Hugely excited to share a truly cross-disciplinary project examining human #islet_architecture in health&in #type_1_diabetes #T1D: combining #machine_learning, elegant #mathematical_modelling in whole section, fixed pancreatic samples stained for all 5 islet hormones:
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doi.org/10.1007/s001...