The effect of mitoTEMPO on the development of hypoxia‐induced pulmonary hypertension in male mice MitoTEMPO targets mitochondrial superoxide (O2•−) but showed no protective effect on chronic hypoxia–induced pulmonary hypertension. Pulmonary artery remodeling and right ventricular remodeling…

This Short Report investigates effects of #mitochondria targeted #antioxidant #mitoTEMPO on roles of mitochondrial reactive oxygen species in HIF-1α stabilization in #hypoxia induced #pulmonary #hypertension in mice.