CSF3 drives IPF by promoting #Myofibroblast activation and ECM deposition in lung fibroblasts, primarily by activating TGF-β signaling, positioning CSF3 as a promising #TherapeuticTarget for IPF.

#STTT #OpenAccess: doi.org/10.1038/s413...

Dr. Boris Hinz (@utoronto.ca), Keenan Research Chair in #Fibrosis Research, specialises in studying the role myofibroblast have in pathological tissue repair.

Join us at #KSStromal26 to hear his take on how the mechanical environment shapes stromal activation. 🧫

#immunology #myofibroblast