Thank you to all who attended & made our educational webinar last Wednesday a successful event! We had attendees from Dubai to Taiwan and back to the US hear our expert panel share their valuable insights & practical advice to #patients!
View webinar here: youtu.be/wSRUQV3hC-4
#PBC #ocaliva
We are partnering with #PBCers Organization for this important patient-facing webinar to give #patients and #caregivers an opportunity to ask "what's do I do? next" after the voluntary withdrawal of #Ocaliva.
Come prepared with questions & register today 💜
liveralliance.org/events/navig...
doi.org/10.1042/BCJ2...: When a drug is effective, but has a narrow therapeutic window. Either throw it out, or try to improve it. Ariane and Audrey-Anne have explored this second option for Ocaliva.
#primary_biliary_cholangitis
#primary_sclerosing_cholangitis
#Ocaliva
#Pharmaco-nutraceutics
This may be super anecdotal but there seems to be a small subset of patients with #PBC who are exquisitely responsive to #ocaliva I saw a patient today who went from an alkphos of 760 to 130 in 2 months. @AutoImmuneLiver #livertwitter @PBCers @PBCFoundation
June 23 is the @US_FDA
PDUFA date for #ocaliva for #NASH BIG decisions looming on the horizon for $MDGL and $ICPT and hopefully good news for #NAFLD #NASH patients #livertwitter ...
topline data from #ocaliva REGENERATE study show drug meeting primary endpoint of reduction of one or more fibrosis stages ir.interceptpharma.com/news-releases/news-relea...
@AASLDtweets Dr. Kowdley reports decline in alkphos with #ocaliva 5-10 mg vs. placebo in AESOP trial. Itching major AE #LiverMg17
The 5 and 10 mg #ocaliva pills are identically priced so up titration does not result in double cost. 10 mg pill is not scored #pbcers
I define inadequate response to UDCA, as ALP > 1.67-times ULN and/or total bilirubin greater than ULN at 1 year #pbcers #ocaliva #pbc
WAC for #ocaliva is $69,350/year or $5,700 for 30 day supply. $ICPT estimates that 19,000 #pbcers have inadequate response to UDCA
Ever wonder how drugs like #ocaliva #zepatier or #epclusa get their name? www.boston.com/lifestyle/health/blog/in...
New therapies for liver disease are coming fast and furious. We eagerly await wholesaler acquisition cost (WAC) for #ocaliva and #Epclusa
Eventful times in Hepatology: news of #stivarga NDA for #HCC, #ocaliva approval for #PBC & anticipated approval of SOF/VEL for #HCV in June
Interconnect Support Services will provide #ocaliva pt education and financial assistance. #pbcers #pbc https://www.interconnectsupport.com/
#ocaliva must be administered at least 4 hours before or after a bile acid binding resin eg: cholestyramine or cholestipol #pbcers #pbc
Increase #ocaliva to 10 mg max after 3 months if inadequate reponse based on AlkPhos blood level & if drug well tolerated #pbc #pbcers
#ocaliva at 5 mg starting dose indicated for non reponse to UDCA after at least 1 year treatment or intolerance of UDCA #PBC #pbcers
PDUFA date for #ocaliva (obeticholic acid) is may 29, 2016. More data at #ILC2016 next week ir.interceptpharma.com/releasedetail.cfm
Label indication for #ocaliva likely for intolerance or incomplete response to UDCA. Start at 5 mg and titrate to 10 mg at 3 month @PBCers
FDA Advisory Committee Unanimously Recommends Accelerated Approval Of #Ocaliva (obeticholic Acid) for #PBC www.thestreet.com/story/13523354/1/fda-adv...
