Re-energizing Acute Myeloid Leukemia Chemotherapy with venetoclax. The central element is preventing tumor cell mitochondrial shape-shifting. #leukemia #lymphoma #aml #venatoclax #opa1

Effects of reduced #mitochondrial #fusion protein Opa1 are examined in mice with endothelial-specific knockout of #Opa1. Reduced mitochondrial fusion in #endothelial #cells increased mesenteric #vascular #reactivity, and increased oxidative stress in #aging #kidney.