L-oxiracetam improves #cognitive outcomes at 90 days after mild-to-moderate #TraumaticBrainInjury, showing greater efficacy and fewer treatment-related adverse events than #Oxiracetam, with comparable overall safety.

#OpenAccess in #STTT: doi.org/10.1038/s413...

Efficacy and safety of L-oxiracetam on cognitive function in patients with traumatic brain injury: a multicentre, randomised, double-blind, phase 3 clinical trial - Signal Transduction and Targeted Therapy Signal Transduction and Targeted Therapy - Efficacy and safety of L-oxiracetam on cognitive function in patients with traumatic brain injury: a multicentre, randomised, double-blind, phase 3...

This study shows that L‑oxiracetam improves #cognition in mild‑to‑moderate #TraumaticBrainInjury patients, outperforming #oxiracetam and placebo, with no major safety concerns, and potential clinical value for managing post‑TBI #CognitiveDysfunction.

#STTT: doi.org/10.1038/s413...