The Ankle Brachial Index (ABI) has been shown to be a specific & sensitive metric for diagnosing #PeripheralArterialDisease. ABI has also been shown to predict mortality & adverse cardiovascular events independent of traditional CV risk factors. #S25ClinicalSkills stan.md/4nGKNl8

Hidradenitis Suppurativa Increases Risk of Peripheral Arterial Disease

HS patients have a 47.8% higher risk of peripheral arterial disease (HR 1.478) over 15 years; clinicians should screen cardiovascular health. Read more: getnews.me/hidradenitis-suppurativa... #hidradenitissuppurativa #peripheralarterialdisease

Check Your Health- New Study Finds Peripheral Artery Disease is Often Underdiagnosed A new study by Intermountain Health researchers finds that peripheral artery disease, a condition that affects more than 10 million Americans over the age of 40

kutv.com/features/hea...

1) PAD is deadly, we observed a >50% mortality rate in men and women over the 13 years
2) PAD is most likely underdiagnosed, it IS undertreated
3) We can DO better

#PeripheralArterialDisease #PAD #StopTheChop #PhysicianAssociate #PALife #PAsDoThat #PAsGoBeyond
#medsky

Support of Home-Based Structured Walking Training and Prediction of the 6-Minute Walk Test Distance in Patients With Peripheral Arterial Disease Based on Telehealth Data: Prospective Cohort Study Background: Telehealth has been effective in managing cardiovascular diseases like stroke and heart failure and has shown promising results in managing patients with peripheral arterial disease (PAD). However, more work is needed to fully understand the effect of telehealth based predictive modelling on the physical fitness of PAD patients. Objective: For this work, data from the Keep Pace study were analyzed in depth to gain insights on temporal developments of patients’ conditions and to develop models to predict the patients’ total walking distance at study end. This could help to determine patients who are likely to benefit from the telehealth program and to continuously provide estimations to the patients as a motivating factor. Methods: This work analyzes continuous patient reported telehealth data, in combination with in-clinic data from 19 Fontaine stage II PAD patients who underwent a 12-week telehealth-based walking program. This analysis granted insights in the increase of the total walking distance of the 6-minute walk tests (6MWT) as a measure for physical fitness, the steady decrease in the patients’ pain and the positive correlation between wellbeing and the total walking distance measured by the 6MWT. Results: This work analyzed trends of and correlations between continuous patient generated data. Findings of this study include a significant decrease of the patients’ pain sensation over time (P

JMIR Formative Res: Support of Home-Based Structured Walking Training and Prediction of the 6-Minute Walk Test Distance in Patients With Peripheral Arterial Disease Based on Telehealth Data: Prospective… #Telehealth #CardiovascularHealth #PeripheralArterialDisease #WalkingTraining #PatientCare

#PeripheralArterialDisease Sex-based difference
BEST-CLI trial

1311♂️ + 519♀️

♀️have better MALE-free or Amputation-free survival than♂️

♀️with surgical bypass has better MALE-free & overall survival than those with endovascular therapy
#JVascSurg 2024
www.jvascsurg.org/article/S074...

Maglev metal-polymer Peripheral Stent

Iron backbone coated with Sirolimus-loaded PLA & Zinc

length of up to 118 mm, strut thickness of 70 μm

noninferior vs Xience stent in🐶6 mo f/up

First-in-man 3 cases

#PeripheralArterialDisease
#NatureComms 2024
www.nature.com/articles/s41...

#PeripheralArterialDisease

#EndothelialCell-derived TRAIL
👉binds to TRAIL-R2 in ECs➡️⏫Sprouting #Angiogenesis
👉#Angiocrine HBEGF➡️⏫Mural cell coverage

Benefits of MD5-1, TRAIL-R agonistic Ab

Amazed to know that EC contributes to 60% plasma TRAIL
#ScienceAdvances 2024
www.science.org/doi/10.1126/...

#MajorAdverseLimbEvents in Patients Undergoing Revascularisation for Lower Limb #PeripheralArterialDisease
A Nationwide Observational Study

N=28021 Swedish National Registry for Vascular Surgery

3.2 y f/up

Joakim Nordanstig lab #EJVES_ESVS 2024
www.sciencedirect.com/science/arti...