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Parafenestella varangrensis sp. nov., a phomenin producing fungus from the Arctic - Scientific Reports Driftwood-associated fungi are a less recognized source of secondary metabolites with diverse biological activities. The main aim of this study was to characterize a driftwood-associated Parafenestell...

Parafenestella varangrensis sp. nov., a phomenin producing fungus from the Arctic

#Antibacterialα-pyrone
#polyketide
#phomenin
#Parafenestella
#marine-derivedfungus

www.nature.com/articles/s41...

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Production of antibacterial compounds by a Steely hybrid polyketide synthase in Dictyostelium

👉 buff.ly/fQYfGky

#Dictyostelium #Polyketide #Biotechnology

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🚨 New marine natural product!

The @mehiri_group reports amesilide, a novel bicyclic polyketide from the marine fungus Amesia nigricolor MUT6601.

#Amesia nigricolor #cytochalasan #polyketide #bis-naphtho-γ-pyrone #antimicrobia #cytotoxicity

www.mdpi.com/1420-3049/30...

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Excited to share our #polyketide #biosensor artwork featured on the cover of Biochemistry! Thanks to several group members for your help with this! #MyACSCover

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Thrilled to share our latest enzyme engineering in ACS Chemical Biology! We improved an enzyme involved in #polyketide starter unit biosynthesis and used it to generate polyketide acceptor substrates in vitro. Kudos to Jared and the team of authors! @pubs.acs.org

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#Polyketide synthases (PKSs) are multi-domain enzymes.

This study examines interactions between the dehydratase and acyl carrier protein domains of a PKS

➡️ bit.ly/3QP4bys

#structuralbiology #AlphaFold

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組立ラインポリケチド合成酵素 (Assembly Line Polyketide Synthases) | 今月の分子 | PDBj 入門 段階的にさまざまな小分子を合成する大規模な多酵素複合体。

段階的にさまざまな小分子を合成する大規模な多酵素複合体。301: 組立ラインポリケチド合成酵素 numon.pdbj.org/mom/301?l=ja #PDB #ポリケチド #polyketide

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