Parafenestella varangrensis sp. nov., a phomenin producing fungus from the Arctic
#Antibacterialα-pyrone
#polyketide
#phomenin
#Parafenestella
#marine-derivedfungus
www.nature.com/articles/s41...
Production of antibacterial compounds by a Steely hybrid polyketide synthase in Dictyostelium
👉 buff.ly/fQYfGky
#Dictyostelium #Polyketide #Biotechnology
🚨 New marine natural product!
The @mehiri_group reports amesilide, a novel bicyclic polyketide from the marine fungus Amesia nigricolor MUT6601.
#Amesia nigricolor #cytochalasan #polyketide #bis-naphtho-γ-pyrone #antimicrobia #cytotoxicity
www.mdpi.com/1420-3049/30...
Excited to share our #polyketide #biosensor artwork featured on the cover of Biochemistry! Thanks to several group members for your help with this! #MyACSCover
Thrilled to share our latest enzyme engineering in ACS Chemical Biology! We improved an enzyme involved in #polyketide starter unit biosynthesis and used it to generate polyketide acceptor substrates in vitro. Kudos to Jared and the team of authors! @pubs.acs.org
#Polyketide synthases (PKSs) are multi-domain enzymes.
This study examines interactions between the dehydratase and acyl carrier protein domains of a PKS
➡️ bit.ly/3QP4bys
#structuralbiology #AlphaFold
段階的にさまざまな小分子を合成する大規模な多酵素複合体。301: 組立ラインポリケチド合成酵素 numon.pdbj.org/mom/301?l=ja #PDB #ポリケチド #polyketide