#proteotoxicstress hashtag - Bluesky

Signal Transduction and Targeted Therapy

@sigtrans-sttt.bsky.social

2 months ago

An overview of #ERAD’s role in maintaining #CellularHomeostasis, protein quality control, and in regulating physiological processes, highlighting its therapeutic implications for #ProteotoxicStress- driven diseases.

#OpenAccess: doi.org/10.1038/s413...

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Nucleic Acids Research

@narjournal.bsky.social

3 months ago

⭐NAR Breakthrough! ⭐

🔬 #tRNA modifications fine-tune #translation; in yeast, their loss slows #ribosomes at hard-to-read codon pairs, causing collisions ⚠️, and cells deploy quality control pathways to prevent #proteotoxicstress and ensure survival.
🧬Read more: doi.org/10.1093/nar/...

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Immunology Podcast

@immunologypodcast.com

5 months ago

📢 New in @nature.com!

Work led by Dr. Zihai Li at the Pelotonia Institute for Immuno-Oncology have shown that #ProteotoxicStress, induced by protein aggregation, is not merely a consequence, but a driver, of the exhausted T cell state.

📄: https://go.nature.com/47zVDog
🎧: https://bit.ly/3LlRCeo

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Trends in Biochemical Sciences

@cp-trendsbiochem.bsky.social

7 months ago

📝 Online now - the Spotlight "MitoTraP: mitochondrial protection for cellular proteostasis" from Vikram Panse and colleagues @ethzurich.bsky.social.

#MitochondrialQualityControl #MitochondrialImport #MitochondrialStress #ProteotoxicStress

Read it here 👉 authors.elsevier.com/a/1lgWM3S6Gf...

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