Study of Biological Diversity Effects of Pesticide Mixtures Highlights Underestimated Risks to Ecosystems - Beyond Pesticides Daily News Blog Pesticide mixtures impact ecosystems with deleterious effects throughout trophic levels, impacting ecosystem functioning and biodiversity.

🐞 A study by @ukceh.bsky.social researchers finds additive effects of synthetic #pyrethroid #insecticide & two #fungicides on biological control, biomass of major invertebrate #trophic groups (position in #foodweb), & soil ecosystem processes in #arable land. #mixtures #uk ➡️ Blog: ow.ly/f9Vr50WYeKy

Reinforcing Scientific Findings, Insecticide Permethrin Found To Alter Gut Microbiome, Causing Obesity - Beyond Pesticides Daily News Blog Studies find the widely used insecticide, permethrin, disrupts the balance of gut microbiota and leads to obesity.

A study in Journal of Agricultural and Food Chemistry finds #permethrin, a commonly used synthetic #pyrethroid insecticide, to be disruptive to the gut #microbiome, altering microbiota & leading to increased formation of fat cells (adipogenesis) and metabolic disorders.

➡️ Blog: ow.ly/xC7f50WS6lZ

Drs Om Singh, Rajnikant Dixit & David Weetman discuss novel #knockdown #resistance #mutations in human #lice: artifacts or emerging resistance? #kdr #pyrethroid #VGSC @lstmnews.bsky.social

authors.elsevier.com/a/1lDKu5Eb1x...

Study Shows Climate Change Exacerbates Synergistic Effects of Synthetic Pyrethroid on Biodiversity - Beyond Pesticides Daily News Blog A study conducted in Germany highlights climate change and the heightened synergistic effects seen with pesticide exposure and food scarcity.

To better understand stressor interactions, @UFZ_de researchers in analyzing #pyrethroid #esfenvalerate exposure discover that the greatest #synergistic effects are under conditions experienced with #climatechange. #foodstress #biodiversity Blog:

ow.ly/fZga50TTy8I

Pyrethroid Insecticide Levels in Newborns that Increase in First Year of Life In addition to mothers exposure, children experience exposure to pyrethroid insecticides earlier in life as levels significantly increase after birth, especially for pyrethroid exposure concentrations in the urine of newborns and children within their first year of life. Therefore, pesticide exposure during pregnancy affects both the mother and child’s health.

A new study highlights that in addition to maternal exposure to #pesticides, #children experience exposure to #pyrethroid #insecticides earlier in life as levels are found to significantly increase after birth.🚼 #health Blog Post:

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Oxidative Stress Measured with Biomarkers Links Pesticide Exposure to Cancer - Beyond Pesticides Daily News Blog 2,4-D, pyrethroid (PRY), and organophosphate (OP) pesticides increase the risk of cancer through oxidative stress (OS). The study highlights that pesticides that increase cancer risk also raise inflammation biomarkers that indicate damage to organs (e.g., liver) via oxidative stress.

2,4-D, #pyrethroid (PRY), and #organophosphate (OP) #pesticides increase the risk of #cancer through #oxidativestress (OS), & inflammation #biomarkers — each pesticide increases the risk of at least three of the six cancers studied. 📈 @XJTU_China Blog:

ow.ly/xsNy50Qu1NW

Child exposure to organophosphate and pyrethroid... : Environmental Epidemiology ods: During spraying season 2018, 38 South African children in two agricultural areas (Grabouw/Hex River Valley) and settings (farm/village) participated in a seven-day study. Child urine and househ...

🆕 from the Bilateral 🇿🇦 🇨🇭Chair in Global & Environmental Health:
Child exposure to #organophosphate and #pyrethroid.
Urine, wristbands and household dust measurements.
21% of the urine biomarker levels exceeded the health-risk threshold for organophosphate.

journals.lww.com/environepide...

New Study Links Synthetic Pyrethroids to Neurodevelopmental Problems - Beyond Pesticides Daily News Blog (Beyond Pesticides, May 5, 2023) Low level exposure to pyrethroid insecticides found in common pesticide brands like RAID and ORTHO result in neurodevelopmental damage to laboratory animals, reinforcing evidence of harm found in epidemiological studies on human exposure to these chemicals. According to research published in PNAS Nexus, mice exposed to the pyrethroid deltamethrin displayed atypical behavior similar to humans with developmental disorders. “We are not saying these mice have autism or that they have ADHD. That’s not the goal here,” said James Burkett, PhD, study coauthor and assistant professor of neuroscience in the UToledo College of Medicine. “What we are saying is that something in their brain has been altered by this exposure and it’s resulting in the same kinds of behaviors that we see in children with autism.” Scientists arrived at this determination by exposing a group of mouse mothers to consistent low levels of deltamethrin in their food during preconception, pregnancy, and lactation. The study notes that the amount of pesticide provided was “well below the benchmark dose for regulatory guidance.” A separate control group was given no pesticide in its food. Offspring from the female mice were then put through behavioral tests on social behavior, restrictive […]

#DN: Study links #exposure to #pyrethroid #insecticides, like #deltamethrin, to #neurodevelopmental changes...

“If you have someone who sprays in your house, this is likely what they’re spraying. It’s #everywhere."
— James Burkett, Ph.D., @UToledoMed

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Pyrethroid Insecticides Associated with Liver Disease - Beyond Pesticides Daily News Blog (Beyond Pesticides, October 7, 2022) Pyrethroid insecticides are associated with the growing worldwide epidemic of non-alcoholic fatty liver disease (NAFLD), a condition that causes swelling of the liver and can eventually lead to cirrhosis, cancer, or liver failure. According to research published in Environmental Science and Ecotechnology, exposure to pyrethroids like bifenthrin can induce gut microbiota dysbiosis (an imbalance in microorganisms in the intestines). This dysbiosis results in abnormal lipid (fat) metabolism and subsequent accumulation of lipids in liver cells, contributing to NAFLD development. Gut microbiota plays a crucial role in lifelong digestion, immune and central nervous system regulation, as well as other bodily functions. Through the gut biome, pesticide exposure can enhance or exacerbate the adverse effects of additional environmental toxicants on the body. Since the gut microbiome shapes metabolism, it can mediate some toxic effects of environmental chemicals. However, with prolonged exposure to various environmental contaminants, critical chemical-induced changes may occur in the gut microbes, influencing adverse health outcomes. Considering NAFLD is becoming the most prevalent form of liver disease, impacting at least 25 percent of the globe, and a growing body of evidence demonstrates the significance gut microbiota play in overall health, safety analyses that currently do not consider the […]

#Pyrethroid #insecticides are associated with growing worldwide #epidemic of non-alcoholic fatty #liverdisease, which causes #liver swelling & can lead to #cirrhosis, #cancer or #liverfailure. #NAFLD #pesticides #Gut #Microbiota #EPAfail #gutmicrobiota

beyondpesticides.org/dailynewsblog/…

Exposure to Synthetic Pyrethroids During Infancy Associated with Developmental Delays in Toddlers - Beyond Pesticides Daily News Blog (Beyond Pesticides, September 1, 2022) Low level exposure to synthetic pyrethroid insecticides at 6-8 months of age is associated with language development delays in two-year old toddlers, according to research published in Neurotoxicology this month. This is the latest study to link this class of chemicals to developmental delays in young children. Despite a steady drum of concerning research, the U.S. Environmental Protection Agency (EPA) in 2019 removed a crucial “safety factor” intended to protect children’s health from synthetic pyrethroids, allowing higher levels of the insecticides to be sprayed on food, in homes, and playing fields around the country.   To investigate the impact of synthetic pyrethroids on language development, scientists enrolled 327 expectant mothers in their third trimester. The mothers, all from rural areas of China, were selected if they had no history of significant pesticide exposure or family history of serious disease. Urine samples were taken from the women during pregnancy, and from infants 6-8 months after birth. Scientists analyzed samples for concentrations of three different synthetic pyrethroid breakdown products (metabolites), including 3-phenoxybenzoic acid (3PBA), 4-fluoro-3-phenoxybenzoic acid (4F3PBA), and cis-2,2dibromovinyl-2,2-dimethylcyclopropane-1-carboxylic acid (DBCA). While 3PBA is a metabolite of many synthetic pyrethroids, 4F3PBA a more specific metabolite of cypermethrin, […]

Low-level exposure to synthetic #pyrethroid #insecticides at 6-8 months of age is associated with language development delays in two-year-old #toddlers, according to research published in #Neurotoxicology this month. #pesticides #EPAfail #infancy #babies

beyondpesticides.org/dailynewsblog/…

Study Confirms Children's Exposure to Mosquito Pesticides Increases Risk of Respiratory Disease - Beyond Pesticides Daily News Blog (Beyond Pesticides, March 3, 2022) Children’s exposure to synthetic pyrethroid insecticides, particularly during the course of mosquito control operations, is associated with increased occurrence of certain respiratory diseases and allergic outcomes, finds research published in the journal Thorax late last month. With a pandemic respiratory virus continuing to spread throughout the world, it has become increasingly important to avoid environmental exposures that can harm lung health. This research underscores the critical need for homeowners, farmers, and vector control officials to shift away from chemical use as the first line of defense against pest problems in order to safeguard children’s health. A total of 303 women and their children participated in the study, which tracked pesticide exposure during pregnancy and then at age five. All participants in the study lived within roughly three miles of a banana plantation. A structured questionnaire captured a range of variables, from socioeconomic status to medical history, local environmental conditions, occupation, and demographics. Researchers collected urine samples from pregnant mothers during the first visit, and their children during the 5-year follow-up. Urine samples were analyzed for metabolites concerning a range of pesticides, including chlorpyrifos, synthetic pyrethroids, the fungicides mancozeb, pyrimethanil, and thiabendazole, and the herbicide 2,4-D. […]

#Children’s exposure to synthetic #pyrethroid #insecticides, particularly during #mosquito control operations, is associated with increased occurrence of certain #respiratory diseases and #allergic outcomes. #health #pesticides #lunghealth #lungdisease

beyondpesticides.org/dailynewsblog/…

Hazardous Synthetic Pyrethroid Insecticides Subject of Lawsuit Against EPA - Beyond Pesticides Daily News Blog (Beyond Pesticides, January 19, 2022) After registering over 300 products containing synthetic pyrethroid pesticides within the last six years, the US Environmental Protection Agency (EPA) has done nothing to safeguard endangered species from toxic exposure to these chemicals, despite legal requirement to do so. This dereliction of duty is set to be the subject of a new lawsuit from the Center for Biological Diversity, which announced its intent to sue EPA. “The EPA admits pyrethroids’ wide-ranging harm to wildlife but still rubberstamps hundreds of pesticide products containing them without assessing their risks to endangered species,” said Lori Ann Burd, environmental health director at the Center. “The EPA needs to get serious and come up with a comprehensive plan to address the havoc these pesticides are wreaking on the environment.” Synthetic pyrethroid insecticides are synthesized derivatives of pyrethrins, which are found in pyrethrum, an extract of dried chrysanthemum flowers. Compared to their natural counterpart, synthetic pyrethroids take significantly longer to degrade in the environment and thus pose longer term risks to humans and wildlife. The chemicals interfere with the proper function of the body’s sodium channels, resulting in harm to the central nervous system. Symptoms of poisoning include headache, nausea, incoordination, […]

#EPA registered 300+ products containing synthetic #pyrethroid #pesticides in last 6 yrs & has failed to safeguard #endangeredspecies from exposure to these #toxicchemicals #despite legal requirement to do so. #CenterForBioDiv intends to sue EPA.

beyondpesticides.org/dailynewsblog/…

#PrecautionaryPrinciple stops this
MT" #Pyrethroid [#pesticide #exposure] biomarker~ *tripled* odds of #ADHD in boys'...