#rightheartdysfunction hashtag - Bluesky

@genesndiseases.bsky.social

2 months ago

#Macrophage κ‑OR mitigates #hypoxic #PulmonaryHypertension by upregulating SCD1, suppressing macrophage inflammation, and limiting smooth muscle proliferation, underscoring κ‑OR activation as a therapeutic strategy for #rightheartdysfunction.

#OpenAccess: doi.org/10.1016/j.ge...

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Genes & Diseases Journal

@genesndiseases.bsky.social

10 months ago

Macrophage κ-opioid receptor inhibits hypoxic pulmonary hypertension progression and right heart dysfunction via an SCD1-dependent anti-inflammatory response

This new study demonstrates that macrophage κ-opioid receptor (κ-OR) inhibits hypoxic pulmonary hypertension (HPH) and #rightheartdysfunction by up-regulating #SCD1, thereby supporting the potential #therapeutic role of κ-OR activation in the treatment of HPH. #medsky

#OpenAccess: buff.ly/X0ORHCk

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Genes & Diseases Journal

@genesndiseases.bsky.social

1 year ago

Macrophage κ-opioid receptor inhibits hypoxic pulmonary hypertension progression and right heart dysfunction via an SCD1-dependent anti-inflammatory response

This new study demonstrates that macrophage κ-opioid receptor (κ-OR) inhibits hypoxic pulmonary hypertension (HPH) and #rightheartdysfunction by up-regulating #SCD1, thereby supporting the potential #therapeutic role of κ-OR activation in the treatment of HPH.

#OpenAccess: buff.ly/wCZ3D4e

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