Phylogenomics and metabolic engineering reveal a conserved gene cluster in Solanaceae plants for withanolide biosynthesis https://doi.org/10.1038/s41467-025-61686-1

Phylogenomics and metabolic engineering reveal a conserved gene cluster in Solanaceae plants for withanolide biosynthesis
doi.org/10.1038/s414...

#Genomics #Bioinformatics #Evolution #SpecializedMetabolism

#FAIRData #bioinformatics #naturalproducts #plantmetabolism #computationalbiology #genomics #plantiSMASH #OpenScience #biorxiv #antiSMASH
#plantscience #specializedmetabolism #biosyntheticgeneclusters #transcriptionfactors #webserver #compbio @antismash.bsky.social

Phylogenomics and metabolic engineering reveal a conserved gene cluster in Solanaceae plants for withanolide biosynthesis - Nature Communications Withanolides are plant steroids with potent bioactivities found in many medicinal plants including Withania somnifera, but their biosynthetic pathway is largely unknown. Here, the authors report the g...

Phylogenomics and metabolic engineering reveal a conserved gene cluster in Solanaceae plants for withanolide biosynthesis
doi.org/10.1038/s414...

#Genomics #Withanolides #SpecializedMetabolism #BiosyntheticGeneCluster #LongReadSequencing #MetabolicEngineering #OpenAccess #OpenData

CoExpPhylo – A Novel Pipeline for Biosynthesis Gene Discovery Background The rapid advancement of sequencing technologies has drastically increased the availability of plant genomic and transcriptomic data, shifting the challenge from data generation to function...

CoExpPhylo - A Novel Pipeline for Biosynthesis Gene Discovery
doi.org/10.1101/2025...

#Bioinformatics #GeneExpression #PathwayDiscovery #BigData #Python #SpecializedMetabolism #OpenAccess

Genetic factors explaining anthocyanin pigmentation differences - BMC Plant Biology Background Anthocyanins are important contributors to coloration across a wide phylogenetic range of plants. Biological functions of anthocyanins span from reproduction to protection against biotic an...

Genetic factors explaining anthocyanin pigmentation differences
doi.org/10.1186/s128...

#Evolution #PlantSci #Flavonoids #Anthocyanins #TranscriptionFactors #Mutation #SpecializedMetabolism

Cacao genome sequence reveals insights into the flavonoid biosynthesis Theobroma cacao is well known for its role in producing cacao. Many different cacao varieties are cultivated in equatorial regions, each distinguished by unique phenotypic traits. An instance of this ...

Cacao genome sequence reveals insights into the flavonoid biosynthesis
doi.org/10.1101/2024...

#TheobromaCacao #Genomics #Bioinformatics #Chocolate #PlantSci #Flavonoids #SpecializedMetabolism #Biochemistry

Biochemistry and Molecular Basis of Intracellular Flavonoid Transport in Plants
doi.org/10.3390/plan...

#PlantSci #Flavonoids #SpecializedMetabolism #Review