Blink and you’ll miss it with IS26… #transposase #insertionsequence #mges #IS26

A transposase-derived gene required for human brain development PGBD5 is required for brain development in humans and mice through genetic and nongenetic mechanisms.

A #transposase -derived #gene required for #human #brain #development | Science Advances www.science.org/doi/10.1126/...

Here you can see a cryoEM structure of the Hermes transposase from the house fly Musca domestica (PDB code: 8EDG)

Rendering by Francisco J. Enguita made with #ProteinImager

3dproteinimaging.com/protein-imag...

#SciArt #molecularart #musca #transposase #hermes #dna #complex #cryoem

Seeking reliable Tn5 Transposase performance?

Discover 𝗧𝗮𝗴𝗺𝗲𝗻𝘁𝗮𝘀𝗲 (𝗧𝗻𝟱 𝗧𝗿𝗮𝗻𝘀𝗽𝗼𝘀𝗮𝘀𝗲) with 𝗦𝘁𝗮𝗻𝗱𝗮𝗿𝗱𝗶𝘇𝗲𝗱 𝗨𝗻𝗶𝘁 (𝗨)—ensuring consistent, high-quality results every time. Simplify workflows and boost confidence in your data.

𝗗𝗲𝘁𝗮𝗶𝗹𝘀: bit.ly/4kLEKLn

#epigenomics #tagmentation #transposase

Programmable gene insertion in human cells with a laboratory-evolved CRISPR-associated transposase Programmable gene integration in human cells has the potential to enable mutation-agnostic treatments for loss-of-function genetic diseases and facilitate many applications in the life sciences. CRISP...

#CRISPR associated #Transposase
Nice!
www.science.org/doi/10.1126/...