Really pleased to see this study led by @raymondkiu.bsky.social now published in @natcomms.nature.com!
We show that probiotics help modulate the preterm infant 👶#microbiome - to reduce ARGs, lower MDR bacteria 🦠 & increase beneficial Bifido ✨
Huge team effort!
www.nature.com/articles/s41...
Some positive stories 👇🏾
“Countries with widespread HPV vaccination and regular cervical cancer screenings are already seeing dramatic reductions in cancer rates. They demonstrate that it’s possible to effectively eliminate the disease”
@scientificdiscovery.dev
ourworldindata.org/hpv-vaccinat...
Here is another map of malaria from 1870
ourworldindata.org/malaria
By “return,” what is meant is that malaria was once endemic in the US. The CDC was founded in Georgia—because it was then the nation’s malaria hotspot. Here’s a Library of Congress map showing past distribution:
www.loc.gov/resource/g37...
In the past 2 years, the US has reported a return of locally acquired malaria. In 2023, Florida & Texas reported P. vivax, then Maryland reported P. falciparum. Now, as far north as Pierce County, WA, a potential local case is under investigation (species TBD).
tpchd.org/news/we-are-...
Panels one and two: Two white mice make their way through a maze. Panel three: Having completed the maze, the two mice are rewarded with some fruit. Two scientists watch them. One says: “Poor little things: all that thought and effort just to earn themselves a little treat.” The second scientist looks at a clock and says: “Coffee time!” Panels four and five: The two scientists make their way through a maze of corridors to a door marked “Canteen” Panel six: The scientists look at the food on offer. One says: “Ooh, Donuts!”
My latest cartoon for @newscientist.com
Cross-kingdom RNA communication in plant–bacterial interaction
- @cp-trendsgenetics.bsky.social Spotlight
www.cell.com/trends/genet...
🧵 Dengue is no longer just a tropical disease - it's showing up in Europe.
This season, France, Italy, and Portugal (Madeira) have already reported locally acquired dengue cases.
Check the latest #CDTR on #dengue here: bit.ly/3TQpDVu
#IdSky #EpiSky #MosquitoBorne #Prevention #PublicHealth
Online now: Epigenetic silencing of interleukin-10 by host-derived oxidized phospholipids supports a lethal inflammatory response to infections
Known effects of arginine on Gram-positive and Gram-negative behavior
It's seem like arginine is emerging as a major host cue. So we wrote an IAI minireview on how arginine levels vary between host tissues and affect microbial behavior.
The review is online today!
journals.asm.org/doi/epdf/10....
@brookeeryan3.bsky.social
#microsky
Join us in Tubingen as a Junior Research Group Leader if you do research on #ESKAPE pathogens and infections and are interested in the highly cooperative environment of @dzif.bsky.social and @cmfi.bsky.social ! Please send your application or forward to colleagues!
uni-tuebingen.de/universitaet...
Wrong Jen Mitchell!
#WeekendRead! #InterferonPower! Stunnenberg Pickkers Kox, Keramati &co show @natimmunol.bsky.org that 2 LPS injections in volunteers mimic the proinflammatory & immunosuppressive phases of #sepsis & found that IFNb treatment restores immune responsiveness in the suppressive phase!
It's a 24 panel illustration, with a rotor (circle) with 24 open circles. For each increment from 1 to 24, an additional circle is filled with blue or pink, in ways that create a symmetrical axis of mass, allowing the rotor to be balanced when rotating at high speeds. The pinks generally show the odd numbers (divisible by 3) while the blues are the paired (divisible by 2) I think?
Weird intersection of math & centrifuge balancing:
Visual proof that it's possible to balance a 24-position centrifuge rotor for any number of equally-filled tubes EXCEPT 1 and 23.
Some of these are anxiety-inducing, though.
(🧑🎨: aliyoh, labrats subreddit)
The cellular mammalian clock regulates Staphylococcus aureus invasion in epithelial cells www.biorxiv.org/content/10.1101/2025.05....
Interested in superbugs, AMR and stress resistance? Join us to do a PhD in the Corrigan lab
@UCDMedicine www.ucd.ie/graduatestud...
Looking to appoint a new or experienced Postdoc to join my team. Investigating novel therapeutics targeting Crohn's disease associated bacteria. Background in Microbiology, Immunology, Biochemistry or related field. 🦠🔬
Apply here: my.corehr.com/pls/trrecrui...
Closing date: 31st May 2025
"Having high densities of Staphylococcus aureus, Haemophilus influenzae, or Moraxella catarrhalis/nonliquefaciens was linked to increased nasal ACE2/TMPRSS2 expression."
The nasal microbiome modulates risk for SARS-CoV-2 infection - eBioMedicine www.thelancet.com/journals/ebi...
I'm delighted to share a useful FREE web-based app portal of powerful bioinformatics tools for microbial genomes and shotgun microbiome sequences!
It's called Micromics and is built by Middle Author Bioinformatics, led by co-founder @ironark.bsky.social
omix.midauthorbio.com
Why do we like vaccines and water systems so much?
It used to be 50/50 whether your kid lived to be an adult. With 4 kids, 94% chance they wouldn't all make it.
Fun times. Maybe let's not do that again.
We don't have magic cures for diseases like measles. We have vaccines.
Molecular interplay between ComEC domains leads to efficient DNA translocation during natural transformation www.biorxiv.org/content/10.1101/2025.04....
New review article on management of S. aureus bacteraemia: jamanetwork.com/journals/jam...
@jama.com @vancefowler.bsky.social #IDSky
Check out the gorgeous Figure which brings together elements of pathogenesis and management: (thread)
Delighted our study (7+ years in the making) is out today in Nature. In a nutshell, 48 hours of antibiotics in week 1 led to impaired vaccine responses up to 15 months later in infants. We show (in-vivo) a probiotic can fix it #microbiome #science #immunology
www.nature.com/articles/s41...
OUT NOW: Inducible transposon mutagenesis identifies bacterial fitness determinants during infection in mice
#microsky 🧪
www.nature.com/articles/s41...
🤣
In 3 days, the number of measles cases in a highly unvaccinated area of Texas has doubled. There are now 48 cases, all of whom are unvaccinated, and 13 of whom have been hospitalized so far, for a hospitalization rate of 27%. This is huge figure in epidemiology. This outbreak will keep spreading.
🌟 Join Institut Pasteur as a Junior Research Group Leader 🌟
Explore host-microbe interactions in key areas like vaccinology, infectious diseases, neuro-immunology, and maternal health.
📅 Deadline: Feb 28, 2025 (few weeks left!)
Apply now ⬇️
Delighted to share our new study. A collaboration with the Thurlow lab. Antibiotic resistance rapidly emerges and thrives in diabetic mice. A worrying coming together of two major and growing health problems worldwide www.science.org/doi/10.1126/...
PhD opportunity in bacterial pathogenesis- deadline tomorrow Feb 13 !
