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Posts by Kat Toropova

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Postdoctoral Research Assistant in Structural Biology at University of Oxford Looking for a new job opportunity in academia? Check out this job opening for a Postdoctoral Research Assistant in Structural Biology on jobs.ac.uk!

Postdoc position open at the Dunn School, University of Oxford #cryoEM #teamtomo #cilia #postdoc, come join us! Deadline 15th May.

www.jobs.ac.uk/job/DRC546/p...

6 days ago 5 5 0 0
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BBC World Service - Discovery, Superbugs: Resistance rising, part 1 Antibiotic resistant bacteria is rising - is a great global crisis on the horizon?

"The [blue plaque] in the red brick building just behind me celebrates the birth of the age of antibiotics"

Prof Chris Tang speaks to the BBC World Service about the world-changing research that took place here in the Dunn School in the 1940s.

Listen now: 🎧https://www.bbc.co.uk/programmes/w3ct6sxh

2 weeks ago 7 3 0 0
Earth and Moon from DSCOVR NASA's Earth Polychromatic Imaging Camera (EPIC) aboard the Deep Space Climate Observatory (DSCOVR) satellite captured this unique view of the Moon as it moved in front of the sunlit side of Earth last month. This view shows the fully illuminated “dark side” of the moon that is never visible from Earth. Ian Regan processed this version of the image to account for the Moon's motion. NASA / NOAA / Ian Regan

Earth and Moon from DSCOVR NASA's Earth Polychromatic Imaging Camera (EPIC) aboard the Deep Space Climate Observatory (DSCOVR) satellite captured this unique view of the Moon as it moved in front of the sunlit side of Earth last month. This view shows the fully illuminated “dark side” of the moon that is never visible from Earth. Ian Regan processed this version of the image to account for the Moon's motion. NASA / NOAA / Ian Regan

I hadn't seen this before. This is pretty remarkable.

Earth and Moon in one NASA photo.

ht @astrokatie.com

2 weeks ago 22977 5243 2 886
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UK Cilia & Centrosomal Network Meeting Spring Meeting 2026 Join us for the annual in-person meeting of the UK Cilia & Centrosomal Network meeting, which for 2026 will be at the University of Leeds!

🥁Calling all Cilia & Centrosome enthusiasts! Registration for the UK Cilia & Centrosome Network Spring meeting in Leeds is open. A homecoming to the place where '9+2' was discovered!

Great opportunity for trainees + ECRs to share work + get community feedback.

www.eventbrite.co.uk/e/uk-cilia-c...

2 weeks ago 9 10 0 0
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Check out our first lab preprint: A real team effort to understand the Plasmodium GAPM proteins, which form part of a essential bridge between the parasite's cytoskeleton and motility apparatus. Below is a sneak peek of some beautiful microscopy - light and electron! www.biorxiv.org/content/10.6...

3 weeks ago 70 25 3 4
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We're excited to announce the beta-release of #RELION-5.1! 🥳 This release has important updates on our #amyloid processing pipeline, as described in this preprint: doi.org/10.64898/202... There are also some tweaks for #teamtomo.

#OpenSoftwareAcceleratesScience

1 month ago 144 47 3 2
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Structural basis of supercoiling-induced CRISPR–Cas9 off-target activity - Nature Cas9 structures explain topology sensing and off-target activation.

Wow!
www.nature.com/articles/s41...

3 weeks ago 5 1 0 0
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A proteome-wide dependency map of protein interaction motifs Nature Structural & Molecular Biology, Published online: 06 March 2026; doi:10.1038/s41594-026-01762-2Ambjørn and Meeusen et al. functionally characterize all reported and a comprehensive set of predicted short linear motifs (SLiMs) using base-editing screens, identifying 450 reported and 264 predicted SLiMs required for normal cell proliferation.

New online: A proteome-wide dependency map of protein interaction motifs

1 month ago 7 3 0 0
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A super detailed protocol + video on Cryo-ExM - Cryo-Expansion Microscopy, led by the labs of our former postdocs @marinelap.bsky.social & @ebertiaux.bsky.social.
Clear, practical, and very useful for anyone doing nanoscale imaging 🚀 app.jove.com/t/68595/expa...

3 months ago 126 32 0 1
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Cryo-EM structure reveals how influenza A virus NEP binds the viral polymerase at a regulatory hotspot, coordinating RNA synthesis and nuclear export. Fantastic collaboration with @loiccarrique.bsky.social and Jon Grimes. www.science.org/doi/10.1126/...

2 months ago 54 27 1 0
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Holy cow the Zhou lab at UCLA is cooking with Isonet 2 - www.biorxiv.org/content/10.6...

Averaging-free direct visualization of ribosome translational state! #teamtomo #cryoet

4 months ago 103 35 2 1

Very proud!

5 months ago 25 5 2 0
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Congratulations to the new cohort of 28 EMBO Young Investigators! They are joining an international network of more than 800 life scientists – Welcome!

Read the press release here:
www.embo.org/press-releases/twenty-ei...

4 months ago 140 32 5 31

very unusual - a tRNA regulated anion channel

4 months ago 57 23 2 2
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Toropova-Roberts lab Christmas lunch 🎄, a joy to work with this lovely bunch!

4 months ago 7 0 0 0
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2025 Pettenkofer Prize awarded to Teresa Thurston - Dunn School The award by the Pettenkofer Foundation recognised Teresa’s contributions to identifying how different bacterial effectors impact the outcome of infection.

Many congratulations Teresa!

Teresa Thurston was awarded the 2025 Pettenkofer Prize, recognising her contributions to identifying how different bacterial effectors impact the outcome of infection.

www.path.ox.ac.uk/news-article...

5 months ago 13 4 1 1
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Converting a kinase through molecular mimicry - Dunn School Published in EMBO Reports, a new study by the Thurston Group reveals how a small virulence protein from Salmonella called SteE, uses molecular mimicry to reprogramme host kinase specificity.

A new study by @thurstonlab.bsky.social reveals how a small virulence protein from Salmonella uses molecular mimicry to reprogramme host kinase specificity.

Find out more: www.path.ox.ac.uk/news-article...

6 months ago 5 2 0 0
Join our Faculty | Department of Biochemistry & Biophysics Call for applications:We invite applications for a tenure-track Assistant Professor position in the newly established Department of Biochemistry and Biophysics. We are conducting an open search for ou...

We are hiring an Assistant Professor of Biochemistry and Biophysics at Weill Cornell Medicine. Come join our collaborative research environment with state-of-the-art facilities in NYC! Application review starts Oct 22.
biochem.weill.cornell.edu/join-our-fac...

6 months ago 38 47 0 0

Huge congrats Girish and team 😍

6 months ago 1 0 1 0
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Happy to share the inaugural paper from the lab. We describe a molecular mechanism for the activation of outer dynein arm motors that power the vital motion of cilia.

Open access link below:
www.nature.com/articles/s41...

Here's a cool animated summary

6 months ago 93 25 8 5
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We had a fantastic time today showcasing our amazing history and cutting-edge research at #OxfordOpenDoors! Visitors learnt about 100 years of medical research, the development of penicillin and our ongoing work on microbiology and AMR. Thanks to all the volunteers!

7 months ago 8 4 1 0
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KIF13B controls ciliary protein content by promoting endocytic retrieval and suppressing release of large extracellular vesicles from cilia Rezi et al. show that kinesin-3 KIF13B regulates ciliary protein content by promoting endocytic retrieval and small extracellular vesicle (EV) release of ciliary proteins while suppressing their relea...

KIF13B controls ciliary protein content by promoting endocytic retrieval and suppressing release of large extracellular vesicles from cilia: Current Biology www.cell.com/current-biol...

7 months ago 33 14 1 0
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Mechanistic studies on axonemal dynein transport to motile cilia - Dunn School Over 30 groups work at the Dunn School to uncover the molecular and cellular mechanisms underlying disease. Discover which research groups are accepting students for our next round of applications.

The annual Dunn School DPhil studentship competition for 2026 is open for applications.

We have a project aimed at understanding the molecular mechanisms of ciliary dynein transport. See details below and please pass on to anyone who might be interested.

www.path.ox.ac.uk/project/mech...

7 months ago 13 9 0 0
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Great time showcasing the amazing science we do at the @dunnschool.bsky.social at #OxfordOpenDoors today!

7 months ago 7 2 0 0
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Leopard-EM: An extensible 2DTM package to accelerate in situ structural biology The ability to generate high-resolution views of cells with cryogenic electron microscopy (cryo-EM) can reveal the molecular mechanisms of biological processes in their native cellular context. The re...

First pre-print from the Lucas Lab led by Matthew Giammar and @joshdcryoem.bsky.social online today! We develop a new, extensible Python implementation of 2DTM and apply it to build pixel size optimization, constrained search and characterize molecular motions in situ www.biorxiv.org/content/10.1...

7 months ago 83 31 8 4

Another exciting opportunity @dunnschool.bsky.social !

Come and be a colleague to a great group of scientists working on the fundamental mechanisms underlying disease, and how to transform health

Please help us find great applicants

7 months ago 24 19 0 0
How to Apply - Dunn School Here you can find more information on how to apply for our PhD programme, including deadlines and application requirements.

The Dunn School PhD programme is live! 🎉

Two projects in our labs:
1) How the motor protein giant dynein-2 works
2) How signalling-essential membrane proteins get into cilia

Cryo-EM/ET, single mol & live-cell fluor microscopy, CRISPR-based genetic tools & more!

www.path.ox.ac.uk/study-with-u...

7 months ago 27 13 0 0
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Applications now open for our PhD studentship programme - Dunn School Applications are now open to apply for our four year, fully-funded PhD programme in Molecular Cell Biology in Health and Disease.

Our PhD studentship programme is officially open; pass it on

If you are looking for a fully-funded PhD in the mechanisms underlying human disease, here are the details...

Great science and a great environment!

www.path.ox.ac.uk/news-article...

7 months ago 21 20 1 0
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Group Leader Career Development Fellowships - Dunn School Are you an early career researcher interested in the cell or molecular mechanisms underlying disease? Do you have an outstanding record and an innovative research plan?

Are you a postdoc interested in the mechanisms of disease?

Do you have a great record and an exciting vision?

Come and start your own lab @dunnschool.bsky.social by applying for sponsorship for early career fellowships.

Deadline 30th September...pass it on!

www.path.ox.ac.uk/work-with-us...

7 months ago 67 67 0 3

Very cool!!

8 months ago 4 0 0 0