We're excited to announce the beta-release of #RELION-5.1! 🥳 This release has important updates on our #amyloid processing pipeline, as described in this preprint: doi.org/10.64898/202... There are also some tweaks for #teamtomo.

#OpenSoftwareAcceleratesScience

#OpenSoftwareAcceleratesScience! 😍

T2-RELION: Task Parallelism, Tensor Core Accelerated RELION for Cryo-EM 3D Reconstruction | Proceedings of the International Conference for High Performance Computing, Networking, Storage and Analysis

Oh wow, this is 🤯 amazing: ~3-fold acceleration of running #relion on A100 GPUs for realistic single-particle refinement by the group of Guangwen Yang at @tsinghuauniversity.bsky.social
.

What a fantastic example of #OpenSoftwareAcceleratesScience, literally! 😍

dl.acm.org/doi/full/10....

Below (by @landerlab.bsky.social) is the 2nd #cryosparc recipe on @biorxivpreprint.bsky.social in a month. I remain worried about closed-source software affecting progress in #cryoEM. We should develop new algorithms instead!

#OpenSoftwareAcceleratesScience

www.biorxiv.org/content/10.1...

In addition to just thinking the work is cool, I'm really proud of the symbiotic relationship teamtomo.org has developed with @bronwynalucas.bsky.social lab over the past year while they built an extensible implementation of 2DTM

#OpenSoftwareAcceleratesScience

www.biorxiv.org/content/10.1...

ChlamyAnnotations/chlamydataset2relion5 at master · Chromatin-Structure-Rhythms-Lab/ChlamyAnnotations Particle annotations for the large-scale cryo-ET dataset of Chlamydomonas reinhardtii - Chromatin-Structure-Rhythms-Lab/ChlamyAnnotations

To all #ChlamyDataset enthusiasts, here is a script that lets you directly import the pre-processed results from EMPIAR-11830 into #RELION v5 for subtomogram averaging:

github.com/Chromatin-St...

#Chlamydomonas #TeamTomo #CryoET #OpenSoftwareAcceleratesScience

Cool Napari plugin from @bwmr.bsky.social's that makes it easier to select specific membranes or groups of membranes that are output from @lorenzlamm.bsky.social's MemBrain🧠🤖 program (playing with MemBrain's connected components). Nice one! #OpenSoftwareAcceleratesScience 🧪🧶🧬🔬

This sounds cool!
#OpenSoftwareAcceleratesScience

Bluesky Network Analyzer Find accounts that you don't follow (yet) but are followed by lots of accounts that you do follow.

FOMO? The below is really good to find people your followers are following, but you are not.
#OpenSoftwareAcceleratesScience
bsky-follow-finder.theo.io

🥳 #OpenSoftwareAcceleratesScience

This is great to hear! 😍 #OpenSoftwareAcceleratesScience

A few months ago, I heard from someone inside DeepMind that they were working hard on making the code suitable for release. I think it is too early to doubt them, and am still optimistic the code will get released soon.
#OpenSoftwareAcceleratesScience

Please note that this is not new: it basically is Bayesian Polishing from #RELION. Academics invent these algorithms, which get picked up by commercial companies. This is great, as #OpenSoftwareAcceleratesScience, but don't forget where it all came from.
pubmed.ncbi.nlm.nih.gov/30713699/

Oh wow, this is BIG: #MotionCor3 and #AreTomo2 for #cryoEM single-particle analysis and #teamtomo are now open-source!! Thank you Shawn Zheng and colleagues at the
Chan Zuckerberg Imaging Institute.

#OpenSoftwareAcceleratesScience

github.com/czimagingins...

And still leaning heavily on your open-source CTFFIND-4.1 program for CTF estimation! #OpenSoftwareAcceleratesScience 😍

We're pleased to announce that #RELION5 is now available for beta testing! 🥳🥳🥳 Download it for free from github.com/3dem/relion/...

#OpenSoftwareAcceleratesScience

The #OpenSoftwareAcceleratesScience code can already be downloaded from the link below. However, it may be worth waiting another week or so, when we release #RELION5 for easier installation and full integration in its GUI.

This brings me an enourmous amount of joy. Thanks @SjorsScheres @biochem_fan & team. #OpenSoftwareAcceleratesScience