π Save the date!
SIICA announces the Virtual School of Immunology 2026, an online event open to anyone interested in gaining a deeper understanding of how the immune system works.
ποΈExpert talks
πΌ A dedicated career-development workshop session
βοΈ More details coming soon!
Posts by Mattia Laffranchi
π£ Save the date!
πΉ Breaking the Maternal Wall | Panel Discussion
π Jan 14 | π 14:00 CET
ποΈ Motherhood & careers in science, academia & industry
π Register: tinyurl.com/yefis2026-ia1
Aroca-CrevillΓ©n, Hidalgo @drusqui.bsky.social et al. identify a #circadian checkpoint in #neutrophils, mediated by the CXCL12βCXCR4 axis, that limits tissue injury by inhibiting their intrinsic circadian clock. rupress.org/jem/article/...
#CardiovascularBiology #InnateImmunity #inflammation
The deadline is approaching! Apply for a PhD position in our group!
π’ Calling all early-career immunologists!
Are you passionate about #science-communication, #outreach and #editorial-strategy? The yEFIS-EJI working group is looking for you! π«΅
Weβre recruiting motivated ECRs to contribute to editorial processes and creating content on yEFIS ECR activities βοΈ
β³ Spring School: The registration deadline has been extended to 23 November! dgfi.org/akademie-fue...
About the DGfI-Spring School on Immunology
dgfi.org/akademie-fue...
@iuis-online.bsky.social @iuisjuniorcomm.bsky.social @dgfi-yi.bsky.social @drfzberlin.bsky.social
Congratulations to the new #yEFIS Boardπ
Looking forward to working together on exciting projects and initiatives π
#EFIS #Immunology
@yefis-immunology.bsky.social
If youβre passionate about shaping the future of the ECR community, join the yEFIS Task Force and get involved!
π docs.google.com/forms/d/e/1F...
Check out:
Unveiling a novel NBAS mutation in common variable immunodeficiency: Expanding the genetic landscape of immunodeficiency disorders
doi.org/10.1016/j.im...
Novel association between NBAS gene and Common variable immunodeficiency (CVID) syndrome
#immunodeficiency #gene #immunobiology
Check out:
Increased co-expression of ICOS and PD-1 predicts poor overall survival in patients with acute myeloid leukemia
doi.org/10.1016/j.im...
High expression of ICOS was associated with poor outcomes in AML patients, with implications for novel AML therapies
#leukemia #ICB #immunobiology
π One week until the #EFIS on Tour Symposium lands in Bucharest, π·π΄
π€ Chance to meet the EFIS Board and network w/ colleagues across Europe
β
Finalize registration today via QR code
π
November 14, 2025 at 13:00
#immunology
@yefis-immunology.bsky.social @hammarieke.bsky.social @bojanpolic.bsky.social
Still think this was one of the best power moves of all time
www.sciencedirect.com/science/arti...
π’ We're SO EXCITED to host Prof. Jean-Laurent Casanova (@casanovalab.bsky.social) for our upcoming YI Seminar. If you're someone excited about the the human genetics of infectious diseases, this ain't a seminar you should miss! Do register at shorturl.at/J6gPh
Check out:
Altered serum concentrations of IL-8, IL-32 and IL-10 in patients with lung impairment 6 months after COVID-19
doi.org/10.1016/j.im...
Serum IL-32, IL-8, and IL-10 levels are associated to lung sequelae after COVID-19.
#COVID-19 #cytokine #immunology #immunobiology
A computational method designs receptors called T-SenSERs, which have predictable signalling responses to tumour microenvironment soluble factors and can be co-expressed with conventional CARs in T cells to enhance their therapeutic activity.
www.nature.com/articles/s41...
Exciting #postdoc opportunity in KL Ung's group!
Understanding the molecular mechanisms of cell wall remodeling in pathogens
Learn more: shorturl.at/gPuFV
Deadline: January 15, 2026
Contact: recruit@ipbs.fr
#Protein #Biochemistry #StructuralBiology #Biophysics #CryoEM
Exciting #postdoc opportunity in T. Gensollen's group!
How early-life interactions between the immune system and microbiota shape lifelong immune imprinting and disease risk
Learn more: shorturl.at/F8hqE
Deadline: January 15, 2026
Contact: recruit@ipbs.fr
#Immunology #Microbiology #Microbiota #Omics
Still relevant in Immunology:
Macrophages: Their role, activation and polarization in pulmonary diseases
www.sciencedirect.com/science/arti...
Key points:
The diverse functions of lung macrophages are attributable to their plasticity
#Macrophage #Immunology #Immunobiology #Elsevier
Check out our latest review on dendritic cells and their roles in cancer immune responses on Cellular & Molecular Immunology:
"Dendritic cell subsets in cancer immunity and tumor antigen sensing"
doi.org/10.1038/s414...
#science #immunology #review #dendriticcell #DC #immunesystem #cancer
The molecular basis for signalling between epithelial and mesenchymal cells in pancreatic cancer has now been revealed
go.nature.com/3Jlu490
Check out:
The phenotype and related gene expressions of macrophages in adipose tissue of T2D mice following MSCs infusion
Key point:
Mesenchymal stem cells induces an M2-like state in macrophages in adipose tissue.
www.sciencedirect.com/science/arti...
#immunology #macrophages #science #elsevier
What is RNA velocity in situ? ChatGPT kept getting it wrong...
So I made this video explaining how RNA velocity in situ infers gene expression dynamics by distinguishing nuclear vs. cytoplasmic expression in spatial transcriptomics data: youtu.be/z9Oxf1hvum0
#AcademicSky
Amazing to have our work finally out!!! ππ€©π
Check out:
Single-cell transcriptome analysis of macrophage subpopulations contributing to chemotherapy resistance in ovarian cancer
Key points:
macrophaged increased their frequency post-chemotherapy in ovarian cancers
www.sciencedirect.com/science/arti...
#Immunology #Immunobiology #Elsevier
Still relevant in Immunology:
Natural and trained innate immunity against Mycobacterium tuberculosis
www.sciencedirect.com/science/arti...
Key points:
M. Tuberculosis and BCG vaccine creates trained immune memory via TLR7/9 signaling.
#Tubercolosis #Vaccine #Immunology #Immunobiology #Elsevier
Check out one of our latest review on Chemerin (RARRES2) and it's roles in the regulation of immune responses on Journal of Leukocyte Biology.
doi.org/10.1093/jleu...
#science #immunology #review #chemerin #immunesystem
Still relevant in Immunology:
Human macrophage polarization in vitro: Maturation and activation methods compared
Key points:
Macrophage polarization is highly dependent on environmental factors.
www.sciencedirect.com/science/arti...
#Science #Immunology #Macrophage #Immunobiology #Elsevier