Function | Monday Insights ☕Call for papers! #Immunobiology and #Inflammation: Emerging Roles in Physiology and #Pathophysiology. Read the articles in this collection: https://ow.ly/g1TA50YwxRv More info about the call: https://ow.ly/Zjov50YwxRw
Join us for tomorrow´s 📢 CIBSS Seminar Series
🗓 09 Dec 2025 | 12:00–13:00
👩🔬 @julianeg.bsky.social, (@mpi-ie.bsky.social)
🎙 Endogenous retroviruses and mouse developmental malformations
📍 Lecture Hall, Institute of Biology I, Hauptstr. 1
See more: kurzlinks.de/iplv
#CIBSS #Science #Immunobiology
👏Looking frwd to talk: #Multiomics #spatial context in #Cancer: from #immunobiology to next-gen #therapies @myesmo.bsky.social (cslide.ctimeetingtech.com/coasis_21467...)
🔥Will reveal best-in-class #trispecific #macrophage #activator #antibody capable of >90% inhibition of #immunoresistant #tumours
Check out:
Unveiling a novel NBAS mutation in common variable immunodeficiency: Expanding the genetic landscape of immunodeficiency disorders
doi.org/10.1016/j.im...
Novel association between NBAS gene and Common variable immunodeficiency (CVID) syndrome
#immunodeficiency #gene #immunobiology
5th Harald von Boehmer Midwinter #Conference
“Advances in #Immunobiology”
📆 24–28 Jan 2026
📍 in Seefeld (Tyrol), Austria
It cover topics ranging from fundamental aspects of innate & adaptive immunity to immune-mediated diseases, cancer, and emerging therapeutic strategies.
➡️ mwc2026.org/index.php
🎉 Last Friday, the master students from the Master Science programs MSc #Biochemistry, MSc #Immunobiology, and MSc Medical #Immunosciences and #Infection celebrated their #graduation.
We congratulate all graduates on their great achievement!
Job Alert
POSTDOC (M/F/X) – IMMUNOLOGY OF AGING
Deadline: 2025-12-31
Location: Germany, Jena
www.academiceurope.com/ads/postdoc-...
#hiring #AgingResearch #Immunology #Postdoc #immunobiology #StemCells #Hematopoiesis #biology #lifescience #biomedicine
Check out:
Increased co-expression of ICOS and PD-1 predicts poor overall survival in patients with acute myeloid leukemia
doi.org/10.1016/j.im...
High expression of ICOS was associated with poor outcomes in AML patients, with implications for novel AML therapies
#leukemia #ICB #immunobiology
Curiosity drove him from a war-torn childhood to leading discoveries in immune regulation. Meet Senad Divanovic, PhD—researcher, mentor and proof that opportunity fuels innovation. scienceblog.cincinnatichildrens.org/road-to-rese...
#immunobiology #WeAreCincyKids @cincychildrens.bsky.social
Job Alert
Head of Bioinformatics Facility (m/f/div)
Deadline: die Stelle bleibt offen, bis sie besetzt ist
Location: Germany, Freiburg
www.academiceurope.com/ads/head-of-...
#Hiring #Bioinformatics #AI #MachineLearning #ComputationalBiology #Freiburg #computerscience #Epigenetics #Immunobiology
Check out:
Altered serum concentrations of IL-8, IL-32 and IL-10 in patients with lung impairment 6 months after COVID-19
doi.org/10.1016/j.im...
Serum IL-32, IL-8, and IL-10 levels are associated to lung sequelae after COVID-19.
#COVID-19 #cytokine #immunology #immunobiology
Still relevant in Immunology:
Macrophages: Their role, activation and polarization in pulmonary diseases
www.sciencedirect.com/science/arti...
Key points:
The diverse functions of lung macrophages are attributable to their plasticity
#Macrophage #Immunology #Immunobiology #Elsevier
Check out:
Single-cell transcriptome analysis of macrophage subpopulations contributing to chemotherapy resistance in ovarian cancer
Key points:
macrophaged increased their frequency post-chemotherapy in ovarian cancers
www.sciencedirect.com/science/arti...
#Immunology #Immunobiology #Elsevier
Are you attending the Symposium on the #Immunobiology of Pattern Recognition Receptors in Lausanne? Our Deputy Editor Gaia Trincucci (@gaiajexpmed.bsky.social) would love to meet you! Be sure to connect with Gaia to discuss your research and JEM's publication process! 🔬💻✍️📄
#InnateImmunity
Still relevant in Immunology:
Natural and trained innate immunity against Mycobacterium tuberculosis
www.sciencedirect.com/science/arti...
Key points:
M. Tuberculosis and BCG vaccine creates trained immune memory via TLR7/9 signaling.
#Tubercolosis #Vaccine #Immunology #Immunobiology #Elsevier
Still relevant in Immunology:
Human macrophage polarization in vitro: Maturation and activation methods compared
Key points:
Macrophage polarization is highly dependent on environmental factors.
www.sciencedirect.com/science/arti...
#Science #Immunology #Macrophage #Immunobiology #Elsevier
Attend tomorrow's #SITC #NCI Assessing the #Tumor #Microenvironment with Systems #Immunology webinar about cutting-edge #computational tools & analytical approaches that reveal the complexities of the #TME & #tumor #immunobiology!
Register now for this exciting #IO program: sitcancer.org/CompIO
BEN+TBI compared to CY+TBI conditioning results in higher proportions of CD103+ cDC1s and robust accumulation of pre-cDC1s. Data shown is from the same mice as in Figure 2. (A) Representative flow cytometry gating of the splenic CD103+ cDC1 population on day 0, showing the FMO control. (B) Quantification of percent CD103+ cDC1s on days 0, +1 and +3 are shown from BEN+TBI or CY+TBI conditioned mice. Naïve mice were used as controls. (C) Total cell numbers of CD103+ cDC1 on day 0 are shown. Representative histograms, percent and MFI among cells positively expressing the activation markers.
🧬✨Did you know a safer way to prevent deadly graft-versus-host disease (#GvHD) during bone marrow transplants may lie in reshaping the immune system? More from Molina et al: doi.org/10.25422/azu... & doi.org/10.3389/fimm.... Image: Molina et al (2020). CC BY 4.0
#OpenData #OpenScience #Immunobiology
Maria and I have written a chapter on Eye Diseases in the Encyclopedia of #Immunobiology, Second edition:
www.researchgate.net/publication/...
An Anglo-Spanish collaboration 😌
Looking forward to the full encyclopaedia being released later this year!
The Center for Cancer #Immunotherapy and #Immunobiology in Kyoto has opened a call for three Junior faculty positions.
Applications are open until July 31st.
#ScienceJobs #Immunology #Immunosky
www.ccii.med.kyoto-u.ac.jp/en/careers-e...
Building Better Immunotherapy: Using a method spearheaded by led by José Ramón Conejo-Garcia, MD, PhD, and Scott Antonia, MD, PhD (pictured here), immune cells are being engineered to find and attack cancer tumors.
🔗: medschool.duke.edu/stories/buil...
#AcademicSky #MedSky #Immunobiology
We're looking forward to taking part in this meeting this October! JEM's Deputy Editor Gaia Trincucci (@gaiajexpmed.bsky.social) will be there – be sure to connect with Gaia to discuss your research and learn about publication 🔬💻✍️📄
#InnateImmunity #Immunobiology
Prizlon-cel could provide a promising treatment option for patients with R/R B-NHL. buff.ly/v7ghHJ4 #hemesky #immunobiology #immunotherapy
Huge shoutout to our MD/PhD student, #DustynLevenson, for an amazing presentation at the #SRI2025 @sriwomenshealth.bsky.social ! She absolutely nailed it with her work on preterm birth immunobiology. Super proud! #Immunobiology #NGLlab @washumedicine.bsky.social
Don’t miss this great opportunity to dive into discussions on innate & adaptive immunity, vaccines, and new technologies in virology!
Looking forward to seeing you there!
— Hannes Vietzen & Daniel Sauter
#Virology #Immunobiology #GfV #ViralInfections #ScienceNetworking
Check out our new #MSc in Biomedical and Clinical Research.
Acquire a broad skill set, selecting a biomedical or clinical focus. Join a vibrant, multi-national community with cutting-edge research projects in #infection & #immunobiology, #AMR, #respiratory #medicine, and more.
DM me for more info
Dr. Antonio Giordano (@antgiordanomd.bsky.social) will be the invited discussant for Concurrent Poster Spotlight Session 12: “Immunobiology Impact on Therapeutic Efficacy” at #SABCS24, his discussion will focus on #Immunobiology 2.
The first mammalian caspase, caspase-1, was identified as the IL-13-converting enzyme involved in cleaving pre-IL-1ß to generate mature IL-13213,219 . The molecular mechanism of programmed cell death in the nematode Caenorhabditis elegans, mediated by Egl-1, Ced-9, Ced-3 and Ced-4, provides a prototypic example of apoptosis. Mammalian caspases (see the figure) were found to be the sequence and functional homologues of C. elegans Ced-3 Initiator caspases (inflammation, apoptosis and pyroptosis) Caspase-1 CARD S Caspase-4 Caspase-5 Caspase-11 Caspase-12 Downstream effector caspases (apoptosis) Caspase-3 Caspase-6 Caspase-7 in mediating apoptosis 21,222 . The genomes of mammals encode multiple caspases (the mouse genome encodes 11 caspases; the human genome encodes 13 caspases), which mediate cell death as well as inflammation". Caspases are classified based on the prodomain length (short or long) and sequence features (CARD or DED) as well as the functions (initiator caspase or downstrea
Intrinsic and extrinsic apoptosis. Extrinsic apoptosis (right) is mediated by the activation of plasma membrane-localized death receptors (such as TNFR1, Fas and TRAIL receptors DR4 and DR5) by their cognate ligands (such as TNF, FasL and TRAIL, respectively). Intrinsic apoptosis (left) can be activated by growth factor withdrawal, mitochondrial damage, DNA damage and chemotherapeutic drugs such as taxol. Activation of BH3-only members of the BCL-2 family, such as transcriptional induction of NOXA and PUMA by p53, post-translational modification of BAD and BIM, and cleavage of BID by caspase-8, induces mitochondrial damage by inactivating ВН3 only Anti-apoptotic Pro-apoptotic Apoptosis pro-survival BCL-2 family members, such as BCL-2, BCL-xL and MCL-1, and activating oligomerization of pro-death BCL-2 family members BAX and BAK. Mitochondrial damage leads to the release of cytochrome c and second mitochondria-derived activator of caspase (SMAC; also known as DIABLO) to promote the acti
MedSky🧪 IDSky #ImmunoSky #Immunobiology .An overview of the major cell death mechanisms, highlighting the latest insights into their complex regulation & execution, their relevance to human diseases.
www.nature.com/articles/s41...
