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Posts by FlyBase

Job Summary: The FlyBase project is an international collaboration of ~35 people distributed at several sites. This position is located at Harvard University, Cambridge, MA. All FlyBase staff work as a part of a team, in which curators and software engineers collaborate extensively. Each site has its own set of responsibilities. The Harvard FlyBase curators focus on curation/annotation of literature and high-throughput data pertaining to the Drosophila genome, transcriptome and proteome. FlyBase is constantly evolving, seeking both to improve and to expand its role within the Drosophila and wider scientific communities. The ideal applicant will be enthusiastic about participating in this process, bringing to the FlyBase group expertise and ideas concerning emerging directions in Drosophila biology and genomic/proteomic analysis. FlyBase is increasingly integrating artificial intelligence and machine learning tools into its curation workflows. The ideal candidate will be open-minded and enthusiastic about exploring AI-assisted approaches to biological data curation, including the use of large language models and AI coding assistants to accelerate and enhance curation tasks.

Job Summary: The FlyBase project is an international collaboration of ~35 people distributed at several sites. This position is located at Harvard University, Cambridge, MA. All FlyBase staff work as a part of a team, in which curators and software engineers collaborate extensively. Each site has its own set of responsibilities. The Harvard FlyBase curators focus on curation/annotation of literature and high-throughput data pertaining to the Drosophila genome, transcriptome and proteome. FlyBase is constantly evolving, seeking both to improve and to expand its role within the Drosophila and wider scientific communities. The ideal applicant will be enthusiastic about participating in this process, bringing to the FlyBase group expertise and ideas concerning emerging directions in Drosophila biology and genomic/proteomic analysis. FlyBase is increasingly integrating artificial intelligence and machine learning tools into its curation workflows. The ideal candidate will be open-minded and enthusiastic about exploring AI-assisted approaches to biological data curation, including the use of large language models and AI coding assistants to accelerate and enhance curation tasks.


Job-Specific Responsibilities: 
	•	Reading and abstracting of data from the current Drosophila literature, including its relationship to human disease, physical interactions, and gene expression 
	•	Evaluating and validating AI generated annotations and curation suggestions, ensuring accuracy and biological relevance before integration into the database 
	•	Using AI coding assistants (e.g. Claude Code, Codex, Gemini) to write scripts for data wrangling, format conversion, and routing curation tasks 
	•	Providing feedback on AI model outputs and refining prompts to help improve automated curation pipelines and annotation quality over time
	•	Annotation and analysis of the Drosophila melanogaster genome, including gene models, mapped mutations, and regulatory features
	•	Together with curators and developers at other sites, interact with broad research community by answering helpmail and giving presentations and tutorials at research conferences 
	•	Handling high-throughput datasets and associated metadata

Job-Specific Responsibilities: • Reading and abstracting of data from the current Drosophila literature, including its relationship to human disease, physical interactions, and gene expression • Evaluating and validating AI generated annotations and curation suggestions, ensuring accuracy and biological relevance before integration into the database • Using AI coding assistants (e.g. Claude Code, Codex, Gemini) to write scripts for data wrangling, format conversion, and routing curation tasks • Providing feedback on AI model outputs and refining prompts to help improve automated curation pipelines and annotation quality over time • Annotation and analysis of the Drosophila melanogaster genome, including gene models, mapped mutations, and regulatory features • Together with curators and developers at other sites, interact with broad research community by answering helpmail and giving presentations and tutorials at research conferences • Handling high-throughput datasets and associated metadata

FlyBase is seeking a new scientific curator at our Harvard University site.
More information here: wiki.flybase.org/wiki/FlyBase...

1 week ago 9 15 1 1
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March 2026 GO Release now available March 2026 GO Release (2026-03-25) Now Available We’re pleased to announce that the March 2026 Gene Ontology release is now live! Quick Access Links Current Release: https://current.geneontology.org...

🐰 The Easter bunny delivered early! The March 2026 Gene Ontology release is here with 38,560 GO terms, 8.8M annotations across 5,557 species. Your functional genomics just got a spring upgrade!
🔗 current.geneontology.org
📋 community.alliancegenome.org/t/8648
#GeneOntology #Bioinformatics #Genomics

2 weeks ago 8 7 0 0

It may be April Fools Day, but it's no prank...the March #TechnicalAdvances are here wiki.flybase.org/wiki/FlyBase...

Want to featured in an upcoming update? Flag your paper with a new resource, technique, or reagent when you #FTYP.

2 weeks ago 3 1 0 0
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A short video of a global heat map of real time pings to FlyBase website from one of our talented developers (not sped up) @flybase.bsky.social @iubiology.bsky.social

3 weeks ago 19 10 2 2

The March Alliance webinar, 'Nomenclature in WormBase & FlyBase, presented by Tim Schedl and Steven Marygold, is now up on the Alliance YouTube channel youtu.be/rhjX0c_vC-s

1 month ago 3 2 0 0

The March Alliance webinar 'Nomenclature in Wormbase & FlyBase' is TOMORROW (Thursday, March 19) at noon EDT. Register by 11pm EDT TONIGHT for a Zoom link tinyurl.com/4f9ycybt

1 month ago 0 3 0 1
Award for "REDfly Database Team and FlyBase Developer Team, Development of online repositories for the dissemination and analysis of Drosophila data"

Award for "REDfly Database Team and FlyBase Developer Team, Development of online repositories for the dissemination and analysis of Drosophila data"

Incredibly honored to be awarded the #Drosophila Community Service Award this morning at #Dros26. A huge 'thank you' to all our users and all the data generators whose hard work has made our own possible.
Look for our completely revised interface with improved search & download coming soon!

1 month ago 9 3 0 0
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FlyBase (@FlyBase@mstdn.science) Attached: 1 video Susan Russo Gelbart accepted on behalf of FlyBase, and gave a rousing acceptance speech. #DROS26 #FlyForward

Susan Russo Gelbart accepted on behalf of FlyBase, and gave a rousing acceptance speech.

#DROS26 #FlyForward

I couldn't successfully upload the video to Bluesky, but have posted it to our Mastodon account:
mstdn.science/@FlyBase/116...

1 month ago 5 0 0 0
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Susan Russo Gelbart accepted on behalf of FlyBase, and gave a rousing acceptance speech.

#DROS26 #FlyForward

1 month ago 1 0 0 0
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Susan Russo Gelbart accepted on behalf of FlyBase, and gave a rousing acceptance speech.

#DROS26 #FlyForward

1 month ago 1 0 0 0
The award to the FlyBase development team recognized Database developers Gil dos Santos, Ian Longden, Christopher J. Tabone, and Pinglei Zhou; Web developers Seth Campbell Victor Strelets, and Jim Thurmond; System administrators Kris Broll and Mark Zytkovicz; Administrative support Carol Sutherland and Jolen Seme; and Program director Susan Russo Gelbart.

The award to the FlyBase development team recognized Database developers Gil dos Santos, Ian Longden, Christopher J. Tabone, and Pinglei Zhou; Web developers Seth Campbell Victor Strelets, and Jim Thurmond; System administrators Kris Broll and Mark Zytkovicz; Administrative support Carol Sutherland and Jolen Seme; and Program director Susan Russo Gelbart.

We appreciate that the award to the FlyBase Developer Team also recognized our support staff, including system administrators, administrative support, and program director.

1 month ago 6 1 3 0
The committee for the 2026 Drosophila Community Service Award for outstanding community service included Michelle Arbeitman (Co-chair), Cale Whitworth (Co-chair), Elizabeth Chen, Lydia Grmai, Amy Kiger, and Steven Marygold.

The committee for the 2026 Drosophila Community Service Award for outstanding community service included Michelle Arbeitman (Co-chair), Cale Whitworth (Co-chair), Elizabeth Chen, Lydia Grmai, Amy Kiger, and Steven Marygold.

The Community Service Award recipients for 2026 were the REDFly Database Team and the FlyBase Developer team, for their roles in development of online repositories for the dissemination and analysis of Drosophila data.

The Community Service Award recipients for 2026 were the REDFly Database Team and the FlyBase Developer team, for their roles in development of online repositories for the dissemination and analysis of Drosophila data.

The 2026 Drosophila Community Service Award was presented earlier this month at #DROS26.
This year's recipients were the REDFly Database Team and the FlyBase Developer Team, for their roles in the development of online repositories for the dissemination of Drosophila data.

1 month ago 14 8 1 0

The March Alliance webinar is this Thurs (3/19), at Noon EDT. Register for the Zoom link by 11pm EDT Weds (3/18) tinyurl.com/4f9ycybt
Tim Schedl (WormBase) & Steven Marygold (FlyBase) will speak on 'Nomenclature in Wormbase & FlyBase'.

If you just got an email with the Zoom link, you are registered

1 month ago 0 2 0 1

Finally, L-TRYPTOPHAN CATABOLISM and
AMINO ACID METABOLISM pathways.

Again, there's links to each of those reports on the FlyBase New in This Release page flybase.org/static/new-t..., in the FB2026_01 section.

1 month ago 2 0 0 0

L-SERINE BIOSYNTHESIS, GLYCINE BIOSYNTHESIS,
GLYCINE CLEAVAGE SYSTEM,
L-PHENYLALANINE AND L-TYROSINE METABOLISM, L-ASPARTATE AND L-ASPARAGINE METABOLISM, L-GLUTAMATE AND L-GLUTAMINE METABOLISM,
L-GLUTAMATE BIOSYNTHESIS (FROM L-PROLINE),
L-ALANINE METABOLISM, L-ARGININE METABOLISM,

1 month ago 2 0 1 0

#MetabolicPathways fans: We've got you in FB2026_01! New reports include (links at flybase.org/static/new-t... ):
L-VALINE CATABOLISM, L-ISOLEUCINE CATABOLISM, L-LEUCINE CATABOLISM, L-LYSINE CATABOLISM,
L-METHIONINE CYCLE, L-METHIONINE SALVAGE PATHWAY,
L-CYSTEINE BIOSYNTHESIS, L-PROLINE BIOSYNTHESIS

1 month ago 3 0 1 0
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New #GeneGroups in FB2026_01:
HOST DEFENSE PEPTIDES flybase.org/reports/FBgg..., NUCLEAR EXOSOME TARGETING COMPLEX flybase.org/reports/FBgg... and MITOCHONDRIAL INTERMEMBRANE SPACE TIM CHAPERONE COMPLEXES flybase.org/reports/FBgg....

1 month ago 2 0 0 0
 FlyBase Funding Update – March 2026

The NHGRI funding for FlyBase has been restored for US-based FlyBase teams but the foreign subaward that supported the essential curation team at the University of Cambridge UK has been terminated. Therefore, the Cambridge UK team now requests annual contributions from fly labs to support curation of new data into FlyBase and the Alliance of Genome Resources. Without these annual contributions, FlyBase will become frozen in its current state and become progressively less useful.

Please visit the ‘Contribute to FlyBase’ wiki page for details of how to contribute.

FlyBase Funding Update – March 2026 The NHGRI funding for FlyBase has been restored for US-based FlyBase teams but the foreign subaward that supported the essential curation team at the University of Cambridge UK has been terminated. Therefore, the Cambridge UK team now requests annual contributions from fly labs to support curation of new data into FlyBase and the Alliance of Genome Resources. Without these annual contributions, FlyBase will become frozen in its current state and become progressively less useful. Please visit the ‘Contribute to FlyBase’ wiki page for details of how to contribute.

FlyBase release FB2026_01 is live!

There is news about FlyBase funding. Go to the FlyBase homepage flybase.org for details.

1 month ago 32 21 1 1

Ever wonder how fly and worm genes, alleles, strains, etc. get their names? Join us at the next Alliance webinar, Thurs. 3/19 at noon EDT. Register for the Zoom link here tinyurl.com/4f9ycybt by 11pm Weds 3/18.

1 month ago 2 1 0 0
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#Dros26 Day 2

What antibodies do you wish we had? Comment below your antibody wishlist!

📸 Drosophila egg chamber labeled with DSHB anti-hts in yellow
🧫 dshb.biology.uiowa.edu/hts-RC

1 month ago 18 8 3 1
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Proud of Dr @tarnopol.bsky.social who received the Sandler Award for “Outstanding Drosophila Thesis” at the fly meeting #Dros26 in Chicago this evening! @genetics-gsa.bsky.social

1 month ago 86 9 7 0

FlyBase talk by Brian Calvi is a half-hour from now! Don't miss it!
‘FlyBase: Past, Present, and Future
7:30 in room Sheraton/Chicago 4-7
#Dros26

1 month ago 3 0 0 0

The only FlyBase event of #Dros26 is TONIGHT! Hear Brian Calvi at 7:30 in Sheraton/Chicago 4-7 speak about ‘FlyBase: Past, Present, and Future’.

1 month ago 3 0 0 1

Reminder: Brian Calvi's FlyBase talk is TOMORROW, March 7, at 7:30-7:45 pm in Room Sheraton/Chicago 4-7 #DROS26

1 month ago 4 3 0 0

#DROS26 starts tomorrow! Sadly, most of FlyBase will not be there this year. Brian Calvi, our Indiana University PI, will be speaking on "FlyBase: Past, Present, and Future" during the Techniques and Technology workshop (Sat. 3/7 7:70-7:45, Room Sheraton/Chicago 4-7).

@briancalvi.bsky.social

1 month ago 6 3 0 2
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It's that time again! The February #TechicalAdvances are up wiki.flybase.org/wiki/FlyBase...
Want to featured in an upcoming update? Flag your paper with a new resource, technique, or reagent when you #FTYP.

1 month ago 1 0 0 1

TODAY is the last day to vote for the Fly Board.
genetics-gsa.org/2026-fly-boa...

2 months ago 0 1 0 0
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We’re running a survey to learn about your experience with AlphaFold DB search results and filters.

Take 5-minutes to share your experience with AlphaFold DB search and have a say in upcoming improvements.

Fill in the survey forms.gle/K7RotPrD9ZPZ...

#AlphaFold #Bioinformatics #StructuralBiology

2 months ago 1 3 0 0
Santa Cruz Developmental Biology Meeting

Registration is OPEN for the 2026 Santa Cruz Meeting on Developmental Biology!!! Please spread the word!

@mads100tist.bsky.social @socdevbio.bsky.social @bsdb.bsky.social @xenbase.bsky.social @isdb.bsky.social @devbiol.bsky.social @the-node.bsky.social

scdb2026.sites.ucsc.edu

2 months ago 46 39 1 4
ISB Presents: Curate This! with Susan Bello
ISB Presents: Curate This! with Susan Bello YouTube video by International Society for Biocuration

We're excited to announce we're starting a podcast "Curate This!" where we interview (bio)curators and have them show us how they work (live!)

In the first episode, we talked with @modcur.bsky.social about curating mouse alleles in @mousegenome.bsky.social

📺️ www.youtube.com/watch?v=rNwv...

2 months ago 1 4 0 1