Minute amounts of helicase-deficient truncated RECQL4 are sufficient for DNA replication - EMBO Reports RECQL4, a RecQ family helicase, is essential for DNA replication and genome stability. Mutations in RECQL4 cause severe human disorders yet we do not fully understand its functions, particularly regar...

🌨️☕👩🏻‍💻

link.springer.com/article/10.1...

Welcome back Earthlings👽😁🧑🏻‍🚀👨🏾‍🚀👨🏻‍🚀👨🏻‍🚀🚀🛸🌑

Chromosome 15q15 Deletion Drives Brain Metastasis in NSCLC Brain metastasis (BM) is a devastating complication of NSCLC, particularly in NSCLC tumors harboring EGFR mutations. However, the genomic alterations driving BM remain poorly understood.

,🌞☕👩🏻‍💻
Chromosome 15q15 Deletion Drives Brain Metastasis in NSCLC - Journal of Thoracic Oncology www.jto.org/article/S155...

🌞☕👩🏻‍💻 Landscape and functional impact of variants of unknown significance of immune response genes in human cancer.

www.linkedin.com/safety/go/?u...

#ChristinaKoch, first #Woman in history to the moon.

Talk about breaking barriers.

@cdnwomenstem.bsky.social #CDNWomenSTEM congratulates the little girl that had a big dream and the woman that fulfilled that dream.

#STEMWomen #LeadByLifting
🚀🌘👩🏻‍🚀🫰🏻

🚀 History is happening.

For the 1st time in 53yrs, humans are on their way to the Moon.

NASA's #ArtemisII crew; Commander Reid Wiseman, Pilot Victor Glover, Mission Specialist Christina Koch, and 🇨🇦 astronaut Jeremy Hansen have lifted off aboard the Orion
#NASA #Artemis #SpaceExploration #Moon

There is always room for Bibimbap.

Also allows one to tailor the CV for each different grant application submitted. Important/relevant information specific to that grant application.

Frontiers | Tumor suppressors LKB1 and SMARCA4 functionally interact to regulate gene expression across diverse biological processes in lung cancer IntroductionThe tumor suppressor kinase liver kinase B1 (LKB1) is known to regulate the activity of the metabolic sensor AMP-activated protein kinase (AMPK),...

💨☕👩‍💻Excited to share our recent discovery. Tumour suppressors LKB1 and SMARCA4 working together to regulate gene expression, acting as a nexus between metabolism and chromatin remodelling. #LungCancer #CancerResearch #Epigenetics #Metabolism #LKB1 #SMARCA4 www.frontiersin.org/journals/cel...

What do Signal Transduction, Neural Networks, Artificial Intelligence and Agentics, all have in common?

COMMUNICATION.

Join us at @dalhousie.bsky.social for an afternoon of science, technology and Guglielmo Marconi.

events.dal.ca/medicine/eve...

Please join us on March 11th to celebrate the Evolution of Communication: Marconi to Agentic AI.

Faculty of Medicine,Tupper Medical Bldg,Theatre A,4pm.

Welcome Italian Ambassador to Canada H.E Alessandro Cattaneo to @dalhousieu.bsky.social @dalhousie.bsky.social
🇨🇦🇮🇹

Open to our Halifax community.

💜🫰🏻

Happy International Women's Day! Today, I am celebrating the incredible strength, resilience, and achievements of women that lift me. In a world facing instability, it's women and girls who are often most affected, facing increased risks and deeper inequalities.

#InternationalWomensDay #IWD2026

Targeting amyloid-β pathology by chimeric antigen receptor astrocyte (CAR-A) therapy Alzheimer’s disease (AD) is the leading cause of dementia and is characterized by progressive amyloid accumulation followed by tau-mediated neurodegeneration. Despite advances in anti-amyloid immunoth...

🌞☕👩🏻‍💻

Targeting amyloid-β pathology by chimeric antigen receptor astrocyte (CAR-A) therapy www.science.org/doi/10.1126/...

At the end of the day.....of CIHR grant submission. 🎻

Neoadjuvant Immunochemotherapy in Resectable NSCLC With SMARCA4 Alterations Neoadjuvant immunochemotherapy has improved pathologic complete response (pCR) rates and event-free survival in resectable NSCLC, yet its efficacy in SMARCA4-altered NSCLC, a subset associated with po...

❄️☕👩🏻‍💻 🧐SCC demonstrates sensitivity with immunochemotherapy, but non-SCC, especially with KRAS+KEAP1/STK11 co-mutations, represents a distinct, immune-cold, high-risk subtype.
www.jto.org/article/S155...

CIHR Funding Crisis: Canada's Health Research Community in Jeopardy | Paola Marignani PhD, EMBA posted on the topic | LinkedIn The recent announcement of a 13.6% success rate (86.4% fail rate) for the Canadian Institutes of Health Research | Instituts de recherche en santé du Canada (CIHR) Fall 2025 PG competition is a stark ...

I have been asked by many of you to share my LinkedIn post regarding internal deadlines. Here you go.
www.linkedin.com/posts/drpaol...

Editing the edits.

Interbreeding between Neanderthals and modern humans was strongly sex biased Sex biases in admixture and other demographic processes are recurrent features throughout human evolution. For admixture between Neanderthals and anatomically modern humans (AMHs), sex bias has been p...

🌞☕👩🏻‍💻😶

Interbreeding between Neanderthals and modern humans was strongly sex biased. www.science.org/doi/10.1126/...

Mitochondrial fission during mitophagy requires both inner and outer mitofissins - EMBO Reports Mitophagy maintains mitochondrial homeostasis through the selective degradation of damaged or excess mitochondria. Recently, we identified mitofissin/Atg44, a mitochondrial intermembrane space-residen...

❄️☕👩🏻‍💻

link.springer.com/article/10.1...

🤦🏻‍♀️🫢

Am I the only one that becomes obsessed with #Olympic 🥌?

Riveting at 5 am!!

Ravi, what features form the basis of the algorithm? Margins, grammar??

And do you know if your discoveries that firm the basis of your grant (ideas, innovations, prelim data) are now part of the "cloud" and are being mined by others? How about the pre-lim data?

Just curious.

Today is National Flag of Canada Day.

At the stroke of noon on February 15, 1965, Canada's red and white maple leaf flag was raised for the very first time on Parliament Hill.

🇨🇦🇨🇦🇨🇦🇨🇦🇨🇦🇨🇦🇨🇦🇨🇦

Wow.
UBC has internal signature deadline that’s about 5 days before submission deadline, which is the day before CIHR deadline.
People can work on Grant between signature deadline and submission deadline.

(Schedule is advanced by ~1week if there’s a private sector partnership)

What is your University internal deadline like? Single deadline or double deadline?
-CIHR LOI date Feb 4, 2026
-Dalhousie FoM internal deadline on Uni server Feb 12, 2026
-Dalhousie ORS internal deadline on Uni server & ResearchNet Feb 17, 2026
CIHR Deadline Mar 4, 2016 @dalhousieu.bsky.social

Today, on the #IWD2026, we celebrate the incredible contributions of women in STEM. It takes everyone working together to break down barriers and inspire the next generation of female scientists, innovators and tech entrepreneurs.
@cdnwomenstem.bsky.social

❄️☕👩🏻‍💻

Proanthocyanidins enhance antitumor immunity by promoting ubiquitin-proteasomal PD-L1 degradation via stabilization of #LKB1 and SYVN1 www.jci.org/articles/vie...

The Gold Within: Family & Fire #cbcsports #milanocortina2026 YouTube video by CBC Sports

❄️☕👩🏻‍💻 Alessia Cara's overview of the Olympic fire in Canada.

Happy Sunday🥇🥈🥉
#MilanoCortina2026

youtube.com/watch?v=pmVK...

Strategy preparation for hardware extraction🤞🏻next month.

Reviewer 2, there is no alternative strategy, the metal has to go.🦵🏻⚙️