🔜 #ELCC26 @myesmo.bsky.social
🔥New horizons in therapeutic targets for thoracic malignancies
☑️ #SMARCA4 #MTAP #Bispecific #Trispecific #ADC
🎙️Chair: Dr. Keith M. Kerr, Dr. Junko Tanizaki
@oncoalert.bsky.social LARVOL #LCSM

Frontiers | Tumor suppressors LKB1 and SMARCA4 functionally interact to regulate gene expression across diverse biological processes in lung cancer IntroductionThe tumor suppressor kinase liver kinase B1 (LKB1) is known to regulate the activity of the metabolic sensor AMP-activated protein kinase (AMPK),...

💨☕👩‍💻Excited to share our recent discovery. Tumour suppressors LKB1 and SMARCA4 working together to regulate gene expression, acting as a nexus between metabolism and chromatin remodelling. #LungCancer #CancerResearch #Epigenetics #Metabolism #LKB1 #SMARCA4 www.frontiersin.org/journals/cel...

Dual loss of #SMARCA2 & #SMARCA4 is rare. PhD candidate Natisha Field in our gp leads an insightful review in #CancerLetters on poor prognosis malignancies with this loss that impacts on #ChromatinRemodeling. #SWISNF #OvarianCancer #LungCancer #epigenetics. Read here:
10.1016/j.canlet.2024.217282