The cartwheel was first visualized ~70 years ago in the symbiont Trichonympha in the wood termite gut. We’ve discovered the cartwheel’s secret: a unique zigzag stacking of SAS-6 tetramers that facilitates the iconic 9-fold symmetry of cilia.
#cellbiology #teamtomo #SAS6 #cartwheel
Yoooo. Are you still just importing cellpack files or doing your own building?
Great looking figure!
1) The Herzik lab is excited to announce our newest preprint in collaboration with the Grotjahn lab! We have developed a surfactant cocktail that seeks to overcome one of the more nefarious problems in #cryoEM, Air-water interface (AWI)-induced damage and preferred orientation (PO).
A YajL protein dimer is shown in green and yellow protein surfaces with an interfacial aspartate/glutamate low-barrier hydrogen bond displayed with mixed-valence orbitals, calculated using quantum mechanics/molecular mechanics for each amino acid. The low-barrier hydrogen bond in the center is highlighted.
Check out our new cover art, made by the talented
@markahix.bsky.social
! It highlights orbital mixing of a low barrier hydrogen bond that spans the dimer interface of YajL.
Small changes tune LBHB character in homologue DJ1. With a point mutation it appears!
pubs.acs.org/toc/bichaw/6...
Slide thanking the protein databank and all the researchers who contributed structures.
At #bps2026 : I loved the special acknowledgement of the @rcsbpdb.bsky.social and the MANY researchers who generated the experimental macromolecular structures that made it possible to build AI models for structure prediction.
You can create images like this in a couple minutes using 100% free software. Check out tutorials by @bradyajohnston.bsky.social
PyMol + Blender is cool. Learned this from @bradyajohnston.bsky.social
💪 NEW VIDEO:
Flying over the A-band of an atomic-scale model of a vertebrate muscle sarcomere. Let's explore the molecular mechanics that make your muscles work.
Rendered using @bradyajohnston.bsky.social 's molecular nodes
Model based on the incredible work of the @raunser-lab.bsky.social lab
Weekend well spent learning Blender and Molecular Nodes by the great @bradyajohnston.bsky.social
My first animation: "Interpretation of NRC2 resistosome assembly on the plasma membrane"
Happy to share our new preprint today! And it looks so nice that I couldn't help myself and made a little video 📺
Great teamwork as always Prof. @medbioinorgchem.bsky.social Prof. Gagliardi, Dr. Wragg and Julia Stebani!
Check it out here: chemrxiv.org/engage/chemr...
Hope you like it a lot!
Visualisation of the structure of PhotoSystem II supercomplex from an algae that is accustomed to low-light conditions (Chlamydomonas reihardtii). It has six yellow antennae complexes which gather light for photosynthesis.
Day 15 of making proteins for #ArtAdventCalendar
The PhotoSystem II supercomplex in plants contains light-gathering antenna complexes (yellow). More antennas means better photosynthesis in low-light conditions (like the version shown with SIX antennas).
More projects: e-nox.net/portfolio/
#SciArt
Visualisation of the structure of the Arc protein, shown as an icosahedral capsid (protein structure depicted as a ribbon), with a point light at its centre, throwing out shadow rays into the surrounding space.
Day 2 of #ArtAdventCalendar
Today's new protein is Arc, a protein found in the brain, which can form icosahedral capsids (like viruses) containing its Arc mRNA cargo. They are linked to regulation of synaptic plasticity and forming long-term memories.
More projects: e-nox.net/portfolio/
#SciArt
How do trypanosomes evolve resistance to sleeping sickness drugs?
Mutations in TbAQP2 🔵 can block melarsoprol and pentamidine 🟠 from entering the cell.
It was a pleasure to create this animation for Simone Weyand.
Read more here: elifesciences.org/reviewed-pre...
#blender #b3d #animation #science
Yes I’m definitely going to play around with something like this. Are you doing elastic network simulations on the alpha carbons?
I _really love_ the resulting aesthetics on this. I've played around with motion blur on structures before but this approach of many more frames & using alpha is a much nicer final look
Proteins are dynamic structures, but structural biology often shows them as static snapshots. Inspired by long-exposure photography and generative art, I built ProteinCHAOS, an artistic tool inspired by molecular dynamics to capture protein flexibility over time, much like long-exposure images.
A few years ago I was tinkering around in Blender, trying to figure out better ways to import molecular data for nicer visuals. I eventually and came up with an add-on that I released 100% free and open source: github.com/BradyAJohnst...
Strange for that to have a life of its own
If there is big biotech announcement happening, #MolecularNodes is being used for it. I only had the realisation in the past day, but it's strange to have my software very quickly become the visual face for $100M announcements and massive scientific breakthroughs.
Your go-to tutorial for simulating mesoscale membranes is here. Look no further for:
-Understanding the state of the field
-A guide for creating new models for your science
-Hands-on tutorials to simulate your very own membranes
See tinyurl.com/punk3tcu and the below 🧵 start your journey 💻
A blobby structure cut open showing its contents which are hélices and loops and light emitting spheres in the middle. This all depicts VPS45 protein
A conglomerate of lipid molecules forming a wall and separating two spaces with different contents
A space-like scene showing a sphere or vesicle about to be hooked by a multi subunit protein complex
Bringing invisible ideas to life.
#sciart #blender3D #illustration
*illustrations created for Mary Munson’s Lab website at UMass Chan Medical School*
ProteinDJ logo
I am thrilled to release ProteinDJ: a high-performance and modular protein design pipeline. Our open-source workflow incorporates #RFdiffusion, #ProteinMPNN, #FAMPNN, #AlphaFold2 and #Boltz-2. It is a fast, free, and fun way to design proteins (1/5)
doi.org/10.1101/2025.09.24.678028 #proteindesign
Protein structures colored teal and purple floating above a reflective surface on a dark background. The protein structures spell out the word "SALAD" in all-capital letters.
Also, shoutout to @blender.org and @bradyajohnston.bsky.social for making it so easy to turn protein structures into nice images!
5/5
so proud to share @jhuapl.bsky.social neuroscience research at #blenderconference2025 @blender.org ❤️
also shoutout to #microscopynodes by @aafkegros.bsky.social, here's to awesome new collabs born at blendercon!!!
New video about caffeine linked here:
youtu.be/fNR-GY-WoAI
Rendered in #blender3d using @bradyajohnston.bsky.social 's brilliant Molecular Nodes extension.
Make sure you check out the incredible coffee from @thegooddotstore.bsky.social 's Keats & Co by visiting keats.watchclockwork.com
What's the opposite of Artificial Intelligence? Naturally Occurring Stupidity?
Whatever it is, that's what I'm here for!
Check out my new film here - made with love, by humans, for humans: youtu.be/iNMxVBnIrwQ
#animation #shortfilm #blender #b3d
Please wait a few seconds and try again
Most complex golden gate wins
