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Posts by Lion Uhl

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Iron and the immune system - Nature Reviews Immunology Iron is crucial for cellular metabolism, but its availability varies greatly within and between individuals and populations. This Review highlights how iron regulates innate and adaptive cellular and ...

#WIMMReads: A new #review in Nature Reviews Immunology by Hal Drakesmith and Joe N Frost explores how #iron shapes immune responses in infection inflammation and cancer.
Read more 👇

#Immunology #Immunology #IronMetabolism #Infection
@rdm.ox.ac.uk @drakesmith-lab.bsky.social @medsci.ox.ac.uk

4 months ago 3 3 0 0

Excited to share our new study, the paper is out today @cp-immunity.bsky.social! Not all Treg cells are the same. We identified two Treg cell subsets with opposing functions in colorectal cancer (CRC). 1/8

4 months ago 16 8 1 3

Friends, it's fun to see the #immunology community continue to grow! I created a 4th Starter Pack to help folks find each other. If you're an immunologist and you don't see yourself on the lists, let me know 🧪

go.bsky.app/PY5tCas

go.bsky.app/FmERUoD

go.bsky.app/6aT6qDS

go.bsky.app/QSEPDoj

1 year ago 120 62 40 5

I’ve made a Starter Pack of #innateimmunity and #inflammation researchers to follow! Please contact me to get added or to suggest others to add. We are just getting started 😎
#immunosky
#academicchatter
go.bsky.app/QqJ9AgB

1 year ago 84 41 41 0

I made a starter pack for those of us interested in or working on T cells. Let me know if you would like to be added or know somebody that should be added.

Looking forward to scientific discussions and updates on our favorite immune cell type!

1 year ago 94 44 66 0
bioRxiv expands on Mastodon and Bluesky bioRxiv - the preprint server for biology, operated by Cold Spring Harbor Laboratory, a research and educational institution

Reminder for newcomers that bioRxiv has Bluesky accounts in every subject category - great way to keep up (please re-skeet) connect.biorxiv.org/news/2023/09...

1 year ago 362 286 6 6

Amazing congrats!! 👏🏻🥳

1 year ago 1 0 0 0

I am really enjoying the surge of people to bluesky but still kind of missing the VERY early career group of people! (Aging in academia is a funny thing) - I went ahead and made this starter pack go.bsky.app/Jq8YaQM - if you would like to be removed/added please let me know

1 year ago 150 88 101 7

Would love to be added too :)

1 year ago 1 0 0 0
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Extensive binding of uncharacterized human transcription factors to genomic dark matter Most of the human genome is thought to be non-functional, and includes large segments often referred to as "dark matter" DNA. The genome also encodes hundreds of putative and poorly characterized tran...

Incredible resource for DNA binding protein specificity from the Codebook consortium.

www.biorxiv.org/content/10.1...

www.biorxiv.org/content/10.1...

www.biorxiv.org/content/10.1...

www.biorxiv.org/content/10.1...

Am reading these in detail & will have a lot to say. Stay tuned for thoughts.

1 year ago 120 47 3 2

Waves of new BlueSky arrivals in last few days!

I’ve been tracking starter packs relevant to molecular/mechanistic/genetic/cellular…etc biology

Hope it’s helpful but warning: now a v long thread!

Probably the last time I can do this...

1 year ago 192 113 15 19
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Early emergence of T central memory precursors programs clonal dominance during chronic viral infection - Nature Immunology T cell memory formation is often described as occurring during the chronic phases of infection. Buchholz and colleagues use the phenomenon of ‘memory inflation’ following cytomegalovirus infection to ...

To populate my Bluesky and people know what I do: I am an MD turned immunology "basic" researcher. In the past I did adoptive T cell therapy and then fate mapping in the Buchholz lab in Munich:
CD8+ T cells in MCMV:
www.nature.com/articles/s41...

1 year ago 15 3 2 0

Hi Steve! The easiest way to build a relevant following is to get added to a starter pack. For Immunology you want this one set up by @rodrahimi.bsky.social. Not sure if this list is already full? go.bsky.app/PY5tCas

1 year ago 7 2 3 0
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First post on Bluesky.

NEW PREPRINT from our lab. It is a first-in-humans study that is very close to my heart. "Quality of vaccination-induced T cell responses is conveyed by polyclonality and high, but not maximum, antigen receptor avidity." www.biorxiv.org/content/10.1...

1 year ago 37 9 1 0