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Posts by Shen Tian 田申

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Zebrafish finds Nemo. New paper with our great collaborators on gap junctional communication in widely divergent species.

www.nature.com/articles/s41...

2 weeks ago 37 15 2 1

Thanks Luca!

1 month ago 0 0 0 0

Amazing peppered moth story from Saccheri lab - same locus, but different structural variants, underly parallel evolution of industrial melanism in the UK and across continental Europe.

1 month ago 36 18 1 0
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A mini review on the seasonal plasticity of butterfly eyespots. www.sciencedirect.com/science/arti...

2 months ago 6 1 0 0

Very excited to share that my first first-author pre-print is out today! Many thanks go out to all of our collaborators, especially those who helped with the fieldwork in Peru - it really wouldn't have been possible without you! 🦋

3 months ago 20 10 1 1
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Evolution rarely invents from scratch.

Our recent study reveals that butterfly eyespots evolved by co-opting an ancient wing vein gene network. New trait, old genes. The study is now published in Communications Biology (featured: Jan26) www.nature.com/articles/s42...

2 months ago 4 1 0 0
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Our eLetter github.com/caseywdunn/s... responding to a recent Science paper was just posted. The paper found more genes with consistent support for sponge-sister than ctenophore-sister. We found several technical issues that, when corrected, reverse the conclusions and recover ctenophore-sister.

3 months ago 131 57 5 9

Congrats @jeffgroh.bsky.social et al. Some avocado trees open female-phase flowers in the morning & then male in afternoon. Others show complementary pattern (m->f), to synchronize pollination of two types. Jeff show this to be a >45Mya polymorphism at a transcription factor across 100s of species.

3 months ago 142 61 1 3
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Causal modelling of gene effects from regulators to programs to traits - Nature Approaches combining genetic association and Perturb-seq data that link genetic variants to functional programs to traits are described.

GWAS has been an incredible discovery tool for human genetics: it regularly identifies *causal* links from 1000s of SNPs to any given trait. But mechanistic interpretation is usually difficult.

Our latest work on causal models for this is out yesterday:
www.nature.com/articles/s41...
A short🧵:

4 months ago 186 83 3 1
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🦣🧬🦣🤯💥We are pleased to share our new paper about ancient RNA expression profiles from the Woolly Mammoth, now published in Cell @cellpress.bsky.social

www.cell.com/cell/fulltex...

If you want to know more, read the 🧵 below:

5 months ago 112 42 1 6
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NEW pub in @science.org 🥳

Is it sponges (panels A & B) or comb jellies (C & D) that root the animal tree of life?

For over 15 years, #phylogenomic studies have been divided.

We provide new evidence suggesting that...

🔗: www.science.org/doi/10.1126/...

5 months ago 284 130 14 30

Hi, I'm setting up a peer support platform for ECRs in ecology & evolution in China, aiming to address a huge problem --- academic burnout driven by hyper-competition and a system that often prioritizes elite background/title over actual research.

#ECR #AcademicSupport #科研互助 #ecology #evolution

5 months ago 8 7 1 0
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a statue of a man 's head with a bunch of paper coming out of it ALT: a statue of a man 's head with a bunch of paper coming out of it

🔥🔥🔥🔥New paper out; a opinion piece in @narjournal.bsky.social with Michael Hackenberg, @panosbino.bsky.social, Kevin K Peterson and @marcfriedlander.bsky.social 🔥🔥🔥🔥

„Knowing is not enough, we must apply“

academic.oup.com/nar/article/...

6 months ago 10 5 0 7
Project overview

Project overview

About the lab

About the lab

Entry requirements

Entry requirements

Funding & eligibility

Funding & eligibility

PhD position for Chinese nationals! London-based, funded by China Scholarship Council & @qmul.bsky.social

"Ecology & genomics of climate adaptation: mapping functional genetic variation in wild insect populations"

shorturl.at/Vfi8W

DM for more info!
#conservation #genomics #ecology #biodiversity

5 months ago 4 5 1 0
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Genomic architecture of egg mimicry and its consequences for speciation in parasitic cuckoos Host-parasite arms races facilitate rapid evolution and can fuel speciation. Cuculus cuckoos are deceptive egg mimics that exhibit a broad diversity of counterfeit egg phenotypes, representing host-ad...

www.science.org/doi/10.1126/...

5 months ago 20 10 0 0
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Wound-induced eyespots on butterfly wings at the intersection of immune response and pigmentation development - BMC Biology Background Butterfly eyespots are striking examples of evolutionary novelty arising through the repurposing of ancestral genetic pathways, including pathways involved in wound healing. Given the activ...

A personal favorite, long time in the making. Adelina and David (@dduneau.bsky.social) were instrumental in getting this done.

doi.org/10.1186/s129...

5 months ago 14 9 0 0
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For those interested in GRN evolution, please join us!

5 months ago 10 8 1 0

Hi Aaron, sure, will pm you

5 months ago 0 0 1 0
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NUS study: A simple DNA switch helps tropical butterflies change wing patterns with the seasons Singapore, 24 October 2025 — Scientists from the National University of Singapore (NUS) have discovered a simple DNA “switch” that helps tropical butterflies adjust the size of their wing eyespots in ...

news.nus.edu.sg/dna-switch-b...

5 months ago 7 3 0 1

A news article about the paper by Jennifer Brisson:

www.nature.com/articles/s41...

5 months ago 3 1 0 0
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This study @science.org finds what appears to be the long-lost RNA subunit of C. elegans telomerase. The TERC RNA is encoded within an intron of a germline-upregulated gene, nmy-2🪱🔬🧬Nematode telomerase RNA hitchhikes on introns of germline–up-regulated genes | Science www.science.org/doi/10.1126/...

5 months ago 46 14 1 1

This is the final piece of my PhD thesis. A big thanks to Bonnie, @tirthabanerjee.bsky.social, Suriya, and @monteirolab.bsky.social for their support! 9/9

5 months ago 0 0 0 0
Cr. to William Piel

Cr. to William Piel

We found a novel promoter of a Hox gene promoting adaptive temperature sensitivities across a large clade of butterflies. This highlights the essential roles of novel cis-regulatory elements in fueling adaptations on a macroevolutionary scale. 8/9

5 months ago 1 0 1 0
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In B. anynana, disrupting this novel promoter reduced the butterfly’s ability to adjust eyespot size with temperature, showing that this genetic element contributed to the evolution of temperature-mediated eyespot size plasticity in satyrid butterflies. 7/9

5 months ago 0 0 1 0
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How is Antp activated in eyespots of a specific clade of butterflies? We found a genetic switch, a promoter, that evolved specifically in satyrid butterflies, and it activates Antp expression specifically in eyespot central cells. 6/9

5 months ago 0 0 1 0
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Disrupting Antp in two satyrid butterflies reduced eyespot size, especially when the insects were raised at warmer temperatures, confirming Antp’s role in boosting the levels of eyespot size plasticity. 5/9

5 months ago 0 0 1 0
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From the tissue-specific transcriptomic data, we pinpointed a Hox gene Antennapedia (Antp), showing higher eyespot expression levels at warmer temperatures. Notbly, among all butterflies with eyespots, Antp is only activated in the eyespots of satyrid butterflies. 4/9

5 months ago 1 0 1 0
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How did satyrid butterflies evolve such temperature sensativities? In a model satyrid Bicyclus anynana, we profiled gene expression from both eyespot and non-eyespot developing wing tissues across two temperatures, using laser-microdissection. 3/9

5 months ago 1 0 1 0
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Many tropical satyrid butterflies look strikingly different in different seasons. In the hot wet season, these butterflies develop large eyespots on their wings. In the cold dry season, these eyespots are small. This change enhances their survival in each season. 2/9

5 months ago 1 0 1 0
Cr. to Shen Tian

Cr. to Shen Tian

My main PhD work @monteirolab.bsky.social is now in @natecoevo.nature.com! We found a Hox gene promoter that helps butterflies🦋adjust their wing eyespots in response to seasonal temperatures🍃🍂, shedding light on the evolutionary origin of phenotypic plasticity. 1/9 www.nature.com/articles/s41...

5 months ago 70 26 2 3