📧 Organizing committee
B. Evano
G. Kardon
O. Pourquie
I. Scionti

🗣️ Speakers
H. Blau
Y. Burelle
E. Chen
B. Cosgrove
K. De Bock
J. Dowling
D. Duprez
J. Enriquez
B. Glancy
M. Gouti
S. Hughes
M. Kim
C. Lanzuolo
A. Mackey
C. Marcelle
A. Mayeuf-Louchart
B. Pedersen
C. Peek
L. Puri
A. Pyle
F. Relaix
W. Roman
P. Zammit

📣 Registration opening: soon! Sign up to be notified coming-soon.embo.org/w26-79

Sessions will be covered from multiple perspectives (development, regeneration, disease), using a variety of model systems (in vitro, in vivo, from invertebrates to human) while exposing the latest developments in genetics, metabolism, -omics, imaging, disease modelling and therapeutic strategies.

🔬 This @embo.org Workshop will bring together leading and emerging scientists to explore the latest developments and future directions in skeletal muscle biology.

🚨 Join us for the EMBO Workshop Muscle development, maintenance & pathology: in vitro models to physiology 🚨

📍 Aghia Pelagia, Greece
📆 11 – 15 October 2026

📣📣 Deadline approaching 📣📣 (Please re-post)

If you are thinking of starting (or moving) your lab, do not miss the opportunity to apply to join us at the
@i2bcparissaclay.bsky.social

Diversity of topics, interdisciplinary environment and excellent platform support! Recommended!

Join IGH as Group Leader - IGH The Institute of Human Genetics invites applications for a Principal Investigator position in its main research areas. Read more...

We are looking for a new group leader to join the IGH (Montpellier, France). I can’t wait to meet my future colleague! Apply :-) More infos here: igh.cnrs.fr/join-igh-as-...

Final version @nature.com of our paper describing unconventional multicellular development in a choanoflagellate inhabiting an extreme environment. A ton of new data since the first @biorxivpreprint.bsky.social preprint (which we've kept updating).

A brief 🧵 (carried over from the old place)

Impaired stem cell migration and divisions in Duchenne muscular dystrophy revealed by live imaging - Nature Communications Using live-imaging in vivo and ex vivo, Sarde et al. show that dystrophic muscle stem cells have precocious differentiation through symmetric divisions and impaired migration, with differential impact...

My first-author PhD paper is out in @natcomms.nature.com 🙌 We developed unique in vivo/ex vivo live-imaging pipelines to uncover new muscle stem cell behaviors in #DuchenneMuscularDystrophy.
Big thanks to all co-authors & the @tajbakhshlab.bsky.social lab!
www.nature.com/articles/s41...

Impaired stem cell migration and divisions in Duchenne muscular dystrophy revealed by live imaging - Nature Communications Using live-imaging in vivo and ex vivo, Sarde et al. show that dystrophic muscle stem cells have precocious differentiation through symmetric divisions and impaired migration, with differential impact...

Bravo Liza, Brendan and colleagues for the elegant work on multiple live imaging strategies to untangle mechanisms of muscular dystrophy! www.nature.com/articles/s41...

@devstempasteur.bsky.social @institutpasteur.bsky.social @cnrsbiologie.bsky.social

Senescence behind the aggressive nature of postpartum breast cancer Postpartum breast cancer is diagnosed five to ten years after giving birth. It is associated with a higher risk of metastasis and a lower survival rate compared with women who have not been pregnant o...

New insight into postpartum breast cancer: senescent cells play a paradoxical role during mammary gland involution.

While essential for normal tissue remodeling after pregnancy, these cells can be hijacked by tumors to promote metastasis.
@hanli-pasteur.bsky.social @devstempasteur.bsky.social

Now published in its final version! Congrats again to all the authors for the amazing work 👏
www.nature.com/articles/s41...

🚨 JOB OFFER in our lab at Institut Pasteur 🚨
We are looking for a research technician! Please repost 🙏

Conditional Dmd ablation in muscle and brain causes profound effects on muscle function and neurobehavior - Communications Biology Generation and characterization of a conditional dystrophin (Dmd) knockout mouse reveals myofiber-specific requirements for muscle homeostasis, and an essential role for Purkinje neuron Dmd in neurobe...

I wanted to highlight our lab's recent #CommsBiology
manuscript: Conditional Dmd ablation in muscle and brain causes profound effects on muscle function and neurobehavior. Credit to Muthukumar Karuppasamy & all collaborators, and team. #Myoblue tinyurl.com/2f4s2ar7

🔬 Train at Institut Pasteur Education Center!

#ASCBcourse 2026 : June 22-July 3

👉2 weeks of world-class science in a legendary institution 🇫🇷
with experts : @tajbakhshlab.bsky.social @zenlabpasteur.bsky.social @stemdevevo.bsky.social
👉 Register here : shorturl.at/PyUHi

#StemCells #PhD #organoids

Modulation of the JAK2-STAT3 pathway promotes expansion and maturation of human iPSC-derived myogenic progenitor cells In this manuscript, Sacco, Caputo, and colleagues demonstrate that modulation of the JAK2/STAT3 signaling pathway during in vitro myogenic differentiation promotes expansion of PAX7+ SMPCs in multiple...

New #stemcellreports paper: Modulation of the JAK2-STAT3 pathway promotes expansion and maturation of human iPSC-derived myogenic progenitor cells. #Myoblue tinyurl.com/yyjhn94p

✨🔬 Get ready for groundbreaking #StemCell research!
Join us in Lyon, Nov 17–19, 2025, for the 7th #FSSCR Annual Meeting.
Connect with leading experts and be part of inspiring scientific exchanges 👇
👉 buff.ly/FRotkAi

@FSSCR_officiel
#FSSCR2025

Mechano-osmotic signals control chromatin state and fate transitions in pluripotent stem cells - Nature Cell Biology McCreery, Stubb et al. show that mechano-osmotic changes in the nucleus induce general transcriptional repression and prime chromatin for cell fate transitions by relieving repression of specific differentiation genes.

How do #stemcells integrate information to coordinate fate decisions? Delighted to finally see our work showing how growth factors regulate the mechano-osmotic state of the #nucleus and #chromatin to control #pluripotency exit out! www.nature.com/articles/s41... see 🧵 👇

Contractile fibroblasts form a transient niche for the branching mammary epithelium Nature Communications - Fibroblasts represent a heterogenous cell population but how their differences reflect their plasticity and origin is not fully understood. Here, the authors map the origin...

So proud of the exciting story from my PhD student Jakub Sumbal on contractile fibroblasts shaping branching morphogenesis!
Fantastic collaboration with the lab of Zuzana Koledova in Prague!
@sumbalovakoledova.bsky.social

It just came out online, check it out here:
rdcu.be/eIIKD

Ventricle position can be remodeled after heart looping!
In a model of heterotaxy we uncovered a new asymmetric morphogenesis process during which the heart reorients its chambers.
So grateful to all the authors for their expertise and input during this long (but fun) ride 💪
Read more here ⬇️

Unraveling the matrisome signatures of quiescent and activated muscle stem cells The extracellular matrix (ECM) niche regulates skeletal muscle stem cell (MuSC) behavior. Using transcriptomic data and 3D imaging, they show that quiescent MuSCs express unique ECM markers, including...

New #stemcellreports paper: Unraveling the matrisome signatures of quiescent and activated muscle stem cells. #Myoblue tinyurl.com/ycyy3nw5

Save the date! The @pasteur.fr Pasteur course on image analysis is announced:

It will happen from the 1st of June to the 5th 2026.

This year there will be only one track: the Early Career Investigator track (beginners). 👇

Flagellar gliding in choanoflagellates Freire-Delgado and Brunet discover a new mode of cell motility in choanoflagellates, the closest relatives of animals. Under mild confinement, choanoflagellate move over surfaces without cell deformat...

New short paper from our lab @currentbiology.bsky.social, in which we discover of a new mode of cell motility for choanoflagellates: flagellar gliding. www.cell.com/current-biol... - A 🧵

Reduced ATP turnover during hibernation in relaxed skeletal muscle Hibernating brown bears, due to a drastic reduction in metabolic rate, show only moderate muscle wasting. Here, we evaluate if ATPase activity of resting skeletal muscle myosin can contribute to this ...

Tuesday, Sept. 16, seminar at noon by Bert Blaauw (Veneto Inst. of Molecular Medicine, Univ of Padova, Italy): Reduced ATP turnover during hibernation in relaxed skeletal muscle
institutcochin.fr/en/agenda/re...
@inserm.fr @cnrs-idf-villejuif.bsky.social @cnrsbiologie.bsky.social @upcite.bsky.social

Do not hesitate to register for Sept 18. Please repost this message.

FSSCR ANNUAL MEETING French Society on Stem Cell Research (FSSCR)

🔬 Don’t miss the 7th Annual FSSCR Meeting in Lyon!
✨ #StemCells research & future clinical applications.
📆 Register by 19 Oct 2025 for regular rates 👉

Sarepta, Sarepta

'The problem is that AAV-based therapies inevitably come with their own risks, and (in my opinion) these should be balanced by impressive efficacy data to make a convincing profile. Obviously this wasn’t present here, which sort of leaves everyone out there to soak up the risk part'