A H3K27me3 reader complex couples H3K27me3 accumulation to nascent transcription of transposable elements in Paramecium - Genome Biology Background The ability to deposit histone H3K27-trimethyl (me3) marks is essential for transcriptional repression by Polycomb Repressive Complex 2 (PRC2). This is largely attributed to Polycomb repres...

Our latest publication is now out at Genome Biology!
link.springer.com/article/10.1...

We uncover a unique association between a H3K27me3 reader complex and active transcription.
A thread with our key findings: (1/8)

#TEsky #Polycomb #transcription #smallRNAs

✍️ The Gazave Lab ( @stemdevevo.bsky.social ) published a new article
📖 @emboreports.org
📃 Multifaceted conserved functions of Notch during post-embryonic neurogenesis in the annelid Platynereis
🔗 link.springer.com/article/10.1...

⬇️ Scientific news published by @cnrsbiologie.bsky.social

✍️ The @romet-jegou-lab.bsky.social Lab contributed to a new publication

📖 Science Advances
📃 Mechanisms of CARMIL dimerization, autoinhibition, and capping protein binding
🔗 www.science.org/doi/10.1126/...

It’s incredibly hard to study lipids in biological membranes on the nanoscale. You need near-perfect information on both membrane ultrastructure and lipid density. Lipid-CLEM, now out in @natcellbio.nature.com brought to you by @mathilda95.bsky.social changes that:
www.nature.com/articles/s41...

If you are interested in doing a postdoc of quantitative biology, biological physics or similar areas… we got you covered 😃 👇🏻

Join IGH as Group Leader - IGH The Institute of Human Genetics invites applications for a Principal Investigator position in its main research areas. Read more...

We are looking for a new group leader to join the IGH (Montpellier, France). I can’t wait to meet my future colleague! Apply :-) More infos here: igh.cnrs.fr/join-igh-as-...

📢 Institut Jacques Monod Seminar

📅 March 20th
📍 Institut Jacques Monod

Tomorrow, Pablo Meyer Rojas will present the Institut Jacques Monod seminar "Pre-training DNA language models to make them understand Biology "

➡️ buff.ly/HIWojfx

Large pink sea urchins in a tub of water, together with some strands of green algae.

We have some exciting guests in the @lionlchristiaen.bsky.social lab facility ✨These beautiful E. esculentus sea urchins collected near Bergen will help guest researcher Antoine Rémond from the @minclab.bsky.social better understand cleavage in echinoderms 🥚

✍️ The @minclab.bsky.social published a new article

📖 Molecular biology of the cell
📃 A cross-species analysis of cell wall mechanosensors
🔗 www.molbiolcell.org/doi/10.1091/...

You are finishing your PhD and looking to continue in science?

The Martin lab @biology-unige.bsky.social has an open postdoctoral position in cell biology to study cell-cell fusion. For more information, please consult mocel.unige.ch/research-gro....

Thanks for reposting!

📢 Institut Jacques Monod Seminar

📅 March 20th
📍 Institut Jacques Monod

Invited by the @minclab.bsky.social, Pablo Meyer Rojas will present the Institut Jacques Monod seminar "Pre-training DNA language models to make them understand Biology "

➡️ buff.ly/HIWojfx

Group Leader Call at the @cbitoulouse.bsky.social in
Genome biology, projects at the interface with devbio will be given particular attention. please share :)
cbi-toulouse.fr/wp-content/u...

Tissue mechanics and systemic signaling safeguard epithelial tissue against spindle misorientation Bosveld et al. identified a multilayered system of safeguards that reuses homeostatic mechanisms to maintain epithelial integrity and cell number in the face of spindle misorientation. This work delin...

How resilient are tissues to cell mispositioning and loss, and how do they restore their cell numbers?

Check our latest work, from @ybellaichelab.bsky.social
Congratulations to all authors.

Artwork from the artist @lale-alpar.bsky.social
(lalealpar.com)

www.cell.com/developmenta...

Upcoming seminar by Meyer Rojas: Pre-training DNA language modelsto make them understand Biology at Institut Jacques Monod, Friday 20 March 2026 at 11:45. More info

Permeability-driven pressure and cell proliferation control lumen morphogenesis in pancreatic organoids - Nature Cell Biology Using pancreatic organoids, Lee et al. show that the balance between epithelial tissue permeability-driven lumenal pressure and cell proliferation affects ductal morphogenesis.

☕Using #pancreatic #organoids, Lee et al. show that the balance between epithelial tissue permeability-driven lumenal pressure and cell proliferation affects ductal morphogenesis.
bit.ly/4qozmjG

Very excited about this new preprint, in which @juliacoronasserna.bsky.social shows how cells ensure that fusion with another cell is irreversible!

www.biorxiv.org/content/10.6...

@biology-unige.bsky.social

👇

Really excited to share our new paper in @nature.com! We uncovered how a physical instability of the cytoplasm coupled with the cell cycle drives cytoplasmic partitioning in early embryos #zebrafish #drosophila. Read more in this🧵 www.nature.com/articles/s41... 🤩
@poldresden.bsky.social @mpi-cbg.de

✍️New preprint from the @minclab.bsky.social

📃 A Cell Size-Dependent Competition Between Geometry and Polarity Governs Nuclear and Spindle positioning in Early Embryos
🔗 www.biorxiv.org/content/10.6...

#JobOffer

💼 H/F Gestionnaire financier-e et comptable
📆 1e avril
📍 Institut Jacques Monod

Candidatez sur le portail emploi CNRS avant le 12 février🔗 emploi.cnrs.fr/Offres/CDD/U...

Latest work from the lab by Aude Nommick et al., in which we propose a "size-scaling" model for microtubule force exertion that regulates centrosome centration vs decentration during embryo development!
@ijmonod.bsky.social

www.biorxiv.org/content/10.6...

Cytoplasmic crowding acts as a porous medium reducing macromolecule diffusion | PNAS Intracellular transport of macromolecules is crucial for the proper functioning of most cellular processes. Although intracellular crowding is know...

Happy to highlight our collaborative work from our @ijmonod.bsky.social team with @destriano.bsky.social, B. Goyeau and M. Chabanon.
Cytoplasmic crowding acts as a porous medium that hinders macromolecular diffusivity.
Plus: a clever way to measure cell volume.
www.pnas.org/doi/10.1073/...

💼 Cell and Molecular Biology Research Engineer (M/F)

📍Institut Jacques Monod, @minclab.bsky.social
📆 June 1st

Apply on the CNRS job portal before February 13th 🔗 emploi.cnrs.fr/Offres/CDD/U...

✍️ The Guichet Lab published a new article

📖 @dev-journal.bsky.social
📃 Girdin controls the pace of 3D tracheal cell intercalation by coupling adherens junctions to the actin cytoskeleton in Drosophila
🔗 journals.biologists.com/dev/article-...

I am very happy (and a bit scared) to present to you what we have been working on over the last 4 years. This manuscript is exactly what I dreamt of when I started the lab and I could not be happier and prouder of the outcome!

📣 Stéphane Peyrégne, responsable d'équipe au sein de l' @ijmonod.bsky.social est lauréat du Prix Georges Brahms 2025 !

Plus d'informations 🔗 www.ijm.fr/prix-georges...

@cnrs-idf-villejuif.bsky.social @upcite.bsky.social

I'm humbled to receive the Paoletti Prize awarded by @cnrsbiologie.bsky.social 😌 and very grateful to present and past mentors !

Really happy to see my PhD first-author paper published in @nature.com! I’m very grateful to have worked with such a great team. Huge thanks to Urša Uršič, Michael Staddon, and Jan Brugués, as well as the @brugueslab.bsky.social, and the @poldresden.bsky.social and @mpi-cbg.de community!

📢 We're hiring a postdoc (33 months) in human evolutionary genomics / paleogenomics / statistical genetics, Paris 🇫🇷
Project on selection on disease-associated variants, integrating ancient genomes, GWAS, and Ancestral Rec. Graphs.
Start May 2026 (flexible).
Apply here: emploi.cnrs.fr/Offres/CDD/U...

La direction de l'Institut Jacques Monod ainsi ses équipes vous présentent leurs meilleurs vœux pour cette année 2026✨

The management of the Institut Jacques Monod and its teams wish you all the best for 2026✨

📣 New preprint from the @minclab.bsky.social

📃 A CROSS-SPECIES ANALYSIS OF CELL WALL MECHANOSENSORS
🔗 www.biorxiv.org/content/10.1...