When do lineage biases first emerge in the epiblast?
They are detectable before gastrulation, but how this early asymmetry is established has remained unclear.
A CRISPRa screen identifies WT1 as an unexpectedly early regulator of formative pluripotency.
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I really appreciate this discussion! Teaching at all levels needs this discussion right now.
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Congratulations 🎊!
Exciting job offer: PhD Program Manager. Lead recruitment, support PhD candidates, and shape doctoral training at a top international life sciences campus. https://ow.ly/3YkN50YAuGM
Institute of Molecular Biotechnology, Max Perutz Labs Vienna, IMP, Gregor Mendel Institute of Molecular Plant Biology
Our work on the role of Ufmylation on ribosome quality control on the ER is out! Great work of two terrific first authors Milica and @alessandrick.bsky.social together with our wonderful collaborators, the one and only Dagdas lab @plantophagy.bsky.social!
The BioOptics facility will expand their team with a Junior Imaging Scientist with a background in Biological Sciences, who is enthusiastic about applying cutting-edge light microscopy for imaging-based research 🔬 Join a collaborative service team at the Perutz today! ➡️ tinyurl.com/5n7m2dyw
It was late last night and I forgot the other organizer! Also thanks to @andraulab.bsky.social and Dom Helmlinger for the organization of the @biolum-montpellier.bsky.social symposium. Listening to @cisselab.bsky.social is always a treat!
New preprint from our lab... We applied our hopping technology to relocate CTCF binding sites to thousands of alternative positions in the Sox2 locus: www.biorxiv.org/content/10.6...
Eliminating the confounding effects of human pluripotent #stemcell co-culture with MEFs:
@grazianomartello.bsky.social @leeboratory.bsky.social @jzylicz.bsky.social and collaborators describe a serum coating approach for feeder-free culture of naïve hPSCs
link.springer.com/article/10.1...
I had a wonderful visit to Montpelier! Beautiful city, fantastic science! Thanks you @laghalab.bsky.social for the invitation.
Congratulations, @yinanwan.bsky.social !
Welcome to the campus!
The Programmable Genomics Lab at @umasschan.bsky.social
just officially launched our site!
We have a "simple" goal: to develop synthetic regulatory elements that target every cell type in every tissue, and control payload dosage/duration
Check it out!
programmable-genomics.github.io
One frame. Many voices. ✨
This International Women’s Day, our Women in Science series features group leader Christa Bücker 🙌
Today, @chribue.bsky.social shares an important perspective on finding role models and becoming one for the next generation 👩🔬
@univie.ac.at
@meduniwien.ac.at
Whoever you are, at least I was invited to talk at the event as a successful grantee.
However, what really stung was the guy who had to comment out loud: well, it just was not a good grant.
I mentioned that I submitted the grant to a different, national funding scheme, where it was initially also rejected but ultimately I was successful, project is by now published.
Today I was asked to talk at a mentoring event for people preparing an application for the ERC. Of course I spend some time on how I prepared for the successful application. However most of the time I spend on the times when it did not work out, grant was rejected.
*New pre-print* I’m delighted to share the second story from my PhD 🥳 We identify 29 severe COVID-19-associated human genetic risk variants that modulate enhancer activity in lung epithelial cells
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www.biorxiv.org/cgi/content/...
The Vienna BioCenter PhD program in Molecular BioSciences will offer 25+ fully-funded positions in the Spring Call which is now open. Check the vacancies in this call: www.vbcphd.at
Institute of Molecular Biotechnology, Max Perutz Labs Vienna, IMP, Gregor Mendel Institute of Molecular Plant Biology
New colleague at the Perutz! Welcome, Danny!
We‘re looking for a motivated Master student to join our team!
Do you want to optogenetically control metabolic activity to see how metabolism affects patterning and morphogenesis? 💡🧫🧬🔬
Then please apply!
#optogenetics #metabolism #devbio #hESCs
Please RT. Thank you!🙏
Congratulations, Elphege and everyone involved! This will definitely lead to some good discussions!
Final registration reminder for SY-Stem 2026. The deadline is on Monday, February 16.
This is such a beautiful preprint! Congrats on the work!
THANK YOU! I share your frustrations, and it is great to see you put it to good use. I normally just rant to myself.
The (Yoav) Voichek lab has opened its gates at the Weizmann Institute, and is actively recruiting students and researchers at all levels - come explore gene regulation and computational genomics in a fun, friendly sprouting lab 🤗🥼⚗️🧪
www.weizmann.ac.il/plants/voichek
It was so much fun!