We‘re looking for a motivated Master student to join our team!
Do you want to optogenetically control metabolic activity to see how metabolism affects patterning and morphogenesis? 💡🧫🧬🔬
Then please apply!
#optogenetics #metabolism #devbio #hESCs
Please RT. Thank you!🙏
🚨 New Preprint from the Paluch & Chalut Labs 🚨
Ana Raffaelli et al show that the stiffness of substrate (in vitro) / basal membrane (in vivo) determine how cells interpret biochemical signals (BMP4) and which fates they acquire
#mechanobiology #hESCs #substratemechanics
doi.org/10.64898/202...
Scientists generated human antral stomach #organoids from #hESCs. Their data suggest the feasibility of inducing gastric insulin-secreting cells in situ in the human stomach.
🔓 More here: https://bit.ly/492AJzq
Jielin Yan (recently graduated 🎉🎉) led the discovery of two enhancers regulating NANOG expression in #hESCs via a #CRISPRi screen. It's part of our larger effort characterizing the functions of enhancers and noncoding variant in development and disease @igvfconsortium.bsky.social
3) #BlueRockTherapeutics and #KyotoUniversityHospital, patients received transplants of dopamine-producing neurones from human embryonic stem cells ( #hESCs) and induced pluripotent stem cells ( #iPSCs) directly into the brain.