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Rita Perlingeiro and Karim Azzag

Rita Perlingeiro and Karim Azzag

Dra. Rita Perlingeiro and Karim Azzag share their insights on the "Progress on cell therapy for skeletal muscle disorders" in the Advanced Drug Delivery Reviews. A must-read for those following the latest in iPSCs & muscle regeneration.

Link: z.umn.edu/perli-azzag-...

#Medicine #StemCells #iPSCs

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Japan’s health authorities have granted conditional approval of two therapies developed from induced pluripotent stem cells, to treat Parkinson’s disease and heart failure.

Read more for FREE in BioNews ⬇️
www.progress.org.uk/worlds-first...

#InducedPluripotentStemCells #iPSCs

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Quick Stem Cells Lab Guide from BioResire!
Master self-renewal, types like iPSCs, and regenerative applications.
Contact for internships: info@bioresire.in #StemCells #StemCellTherapy #RegenerativeMedicine #iPSCs #StemCellResearch #Biotechnology #BioResire #LifeSciences #PluripotentStemCells

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REPROCELL Introduces Cutting-Edge GMP Master Cell Bank for iPSCs REPROCELL has launched a GMP Master Cell Bank for iPSCs, streamlining the cell therapy development process with FDA compliance and integrated services.

REPROCELL Introduces Cutting-Edge GMP Master Cell Bank for iPSCs #USA #Beltsville #iPSCs #REPROCELL #GMP_Master_Cell_Bank

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iPSCs: Progress, Opportunities, and Challenges | Keystone Symposia Join us at the Keystone Symposia on iPSCs: Progress, Opportunities, and Challenges, January 2026, in Kyoto, with field leaders!

Thank you to the Center for iPS Cell Research and Application (CiRA) for an outstanding meeting in Kyoto celebrating 20 years of iPS cell research!

Missed it? Watch all talks on demand: keysym.us/KSiPSCsPricing

Learn more: www.cira.kyoto-u.ac.jp/e/pressrelea...

#KSiPSCs #iPSCs #stemcells

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Missed the sold-out iPSCs meeting in Kyoto? Now you can watch it on demand. 🇯🇵🧪
Stream iPSCs: Progress, Opportunities, and Challenges:
🔗 keysym.us/KSiPSCsPricing

#KSiPSCs26 #stemcells #iPSCs #regenerativemedicine

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We’re at Frontiers in Stem Cell Innovation 2026 at the Babraham Institute!

Our BD Manager, Dr. Dammy Olayanju, is there. Say hi and chat peptide hydrogels, stem cells, and organoid research.

www.peptimatrix.com

#StemCells #Organoids #iPSCs #DrugDiscovery #Hydrogels

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Greetings from Kyoto at the iPSCs Conference! 🎉 Congrats to the National Center for Advancing Translational Sciences scholarship winners - supporting emerging leaders shaping the future of translational science.

#KeystoneSymposia #iPSCs #StemCells #FutureOfScience

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Video

⚡ Rewrite cellular destiny ⚡

Master iPSC reprogramming with world-class instructors from Harvard Stem Cell Institute, Institut Pasteur & CEA!
From Yamanaka's 2006 breakthrough to today's clinical-grade methods 🧬
📆 June 22-July 3, 2026 | Paris
👉 shorturl.at/PyUHi
#StemCells #iPSCs #ASCBcourse

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Tau #oligomers modulate synapse fate by eliciting progressive bipartite #synapse dysregulation and synapse loss

Kristeen A. Pareja-Navarro, Christina D. King, Grant Kauwe...Tara E. Tracy @buckinstitute.org #AlzheimersDisease #iPSCs

link.springer.com/article/10.1...

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They developed a novel in vitro model of TBEV-related neuropathogenesis, using human motor neurons (hMNs) derived from #iPSCs. Given the motor symptoms associated with TBEV, including paralysis, hMNs provide an effective model for TBEV associated #neuropathology.

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2025 at EBiSC: new iPSCs, new partners, continued excellence. – EBiSC Distribution

🎄 An end of year message from EBiSC.
Thank you to all our partners, collaborators and Users! Wishing you a peaceful festive season and a successful year ahead in 2026.
distribution.ebisc.org/2025/12/2025...
#iPSCs #UKDRI #CureCMD #Angelmansyndrome #Alzheimer's

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Human neurovascular cell database

We first optimized differentiation of #iPSCs into #BBB cell types and performed in-depth characterization using RNA-seq and #proteomics, benchmarking them against primary cells. The results are available in our new database 💻 check it out here: dbneurovasp.isd-muc.de
3/4

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To build such a model, we first optimized differentiation of BBB cell types from #iPSCs, including endothelial (EC), mural and glia cells, and deeply characterized those using proteomics and RNAseq, also benchmarking them against primary cells and datasets from brain. 3/10

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🌟... #functionalgenomics @fg-pgc.bsky.social travels from Germany to Toronto, Canada, @utoronto.ca where Dr PAVEL POWLOWSKI recently obtained his PhD👨‍🎓and studies #genes #endocannabinoids and human cells in a dish #iPSCs in #bipolardisorder. 🧬🧠

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Join us this Friday morning for the @uam-ibmib.bsky.social seminar: Józef Dulak from the Jagiellonian University @jagiellonskiuni.bsky.social will give a talk on the modeling cardiac and muscle diseases with induced pluripotent stem cells! #IPSCs

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KSQA: Dr. Shinya Yamanaka (iPSCs)
KSQA: Dr. Shinya Yamanaka (iPSCs) YouTube video by KeystoneSymposia

📢 Early-career stem cell researchers - last chance! Save $250 on registration for iPSCs: Progress, Opportunities & Challenges by Nov 25 (11:59pm MST). Join Shinya Yamanaka in Kyoto this January.
🎥 youtu.be/HScg4drEtSs

🔗 keysym.us/KSiPSCs26

#KSiPSCs26 #stemcells #iPSCs

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💖 “We found love in a hopeless plate” – Two iPSC colonies merge into a heart-shaped cluster in this image by Claudia De Guidi from our 2025 image competition. It captures patient-derived fibroblasts being reprogrammed into #iPSCs for disease modeling & research at our Cell & Gene Technologies Core.

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New & Noteworthy: Upcoming Conference Highlights Keystone Symposia's 2026 conference season boasts an exciting line-up spearheaded by Nobel Laureates and field leaders that explore the frontiers of biology and medicine.

🔥 @keystonesymposia.bsky.social’s 2026 season preview!

🧬 Featuring:
#iPSCs w/ #NobelLaureate Dr. Shinya Yamanaka & @takeda-pharma.bsky.social
• Thomas A. Wynn (Pfizer) on #stromalimmunology & #fibrosis
#DrugDiscovery #embryology #CKD

🔗 keypoint.keystonesymposia.org/home/upcomin...

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📢 We’re excited to to be attending ELRIG Drug Discovery 2025 in Liverpool this week!

Our team is looking forward to connecting with researchers - our core goal is to support and enable iPSC research so come and tell us what you need from an iPSC repository!

#ELRIG2025 #DrugDiscovery #iPSCs

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KSQA: Dr. Shinya Yamanaka (iPSCs)
KSQA: Dr. Shinya Yamanaka (iPSCs) YouTube video by KeystoneSymposia

🚨 Deadline: Oct 15 (11:59pm MDT) 🚨

Early-career scientists - last chance to submit abstracts or scholarship apps for iPSCs: Progress, Opportunities & Challenges! Celebrate 20 yrs of iPSC breakthroughs w/ Shinya Yamanaka.

🎥 youtu.be/HScg4drEtSs
🔗 keysym.us/KSiPSCs26

#KSiPSCs26 #iPSCs #stemcells

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New & Noteworthy: Upcoming Conference Highlights Keystone Symposia's 2026 conference season boasts an exciting line-up spearheaded by Nobel Laureates and field leaders that explore the frontiers of biology and medicine.

Discover New & Noteworthy @keystonesymposia.bsky.social conferences coming up this season on the Keypoint blog - featuring #iPSCs organized by #NobelLaureate Shinya Yamanaka with partner Takeda Pharmaceutical Co,, Inc., #StromalImmunology, #KidneyDisease, #AIDrugDiscovery & more! keysym.us/26Season

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If you wanna know all the details about the role of this interesting protein, please read the full pre-print on bioRxiv!
#RBP #neurogenesis #iPSCs #scRNA-seq #STAU2

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We have two new job openings for #ArranzLab new ERC project starting in 2026 about #iPSCs #astrocytes #chimeras

#ProjectManager
#Postdoctoral_researcher

Check them out!
www.achucarro.org/job-opportun...

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A graphic with a blue background features a white quote: "Preclinical studies currently rely on in vivo animal models, including transgenic and aged specimens...[brain organoids]-based research aims to reduce the use of these models, facilitating faster and easier scaling of therapeutic interventions for AD...[and] serve as valuable ex vivo targets for monitoring pharmacological interventions during disease progression, offering insights that may lead to personalized therapies.” Below the text, a citation appears in small white font: "Dolciotti C, Righi M, Grecu E, et al. The translational power of Alzheimer's-based organoid models in personalized medicine: an integrated biological and digital approach embodying patient clinical history. Front Cell Neurosci. 2025;19:1553642. doi:10.3389/fncel.2025.1553642.” In the lower right corner, there is a colorful illustration of a human brain model divided into regions: yellow, pink, blue, purple, orange, and red.

A graphic with a blue background features a white quote: "Preclinical studies currently rely on in vivo animal models, including transgenic and aged specimens...[brain organoids]-based research aims to reduce the use of these models, facilitating faster and easier scaling of therapeutic interventions for AD...[and] serve as valuable ex vivo targets for monitoring pharmacological interventions during disease progression, offering insights that may lead to personalized therapies.” Below the text, a citation appears in small white font: "Dolciotti C, Righi M, Grecu E, et al. The translational power of Alzheimer's-based organoid models in personalized medicine: an integrated biological and digital approach embodying patient clinical history. Front Cell Neurosci. 2025;19:1553642. doi:10.3389/fncel.2025.1553642.” In the lower right corner, there is a colorful illustration of a human brain model divided into regions: yellow, pink, blue, purple, orange, and red.

🧠 This mini review explores how #organoids from patient-specific #iPSCs mimic the structural & functional complexities of the human brain, as well as be used to study AD pathology.

🏛️ @unipisa.bsky.social

www.frontiersin.org/journals/cel...

6/

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🎉 We're excited for the UK Stem Cell Network Inaugural meeting next week!
Looking forward to great talks, new ideas, and connecting with UK researchers.

Who else is here? Let’s meet up!

#UKSCN #iPSCs #Research #StemCells

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Figure 3A from the paper linked in the next post: "Prevention and rescue of neural commitment deficits in AxD neural organoids. (A) Protocols that were used to generate neural organoids in the prevention and rescue experiments. For full protocol description, see methods section."

Figure 3A from the paper linked in the next post: "Prevention and rescue of neural commitment deficits in AxD neural organoids. (A) Protocols that were used to generate neural organoids in the prevention and rescue experiments. For full protocol description, see methods section."

Using #iPSCs from patients with #AlexanderDisease, @umcutrecht.bsky.social scientists discovered that mutations in the protein GFAP disrupt neuroectodermal lineage commitment in neural #organoids, supporting its role as an early modulator of #neurodevelopment.

#neuroskyence #devbio 🧪

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In case you missed it, be sure to watch July's instalment of the Discover ASAP!

Ricardo Márquez Gómez from Wade-Martins Lab discussed their scalable microfluidic platform that enables the study of human neuron microcircuitry, connectivity, and regeneration in vitro 🔬

#OpenScience #PD #iPSCs

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Modeling rare genetic disease with patient-derived induced pluripotent stem cells: reassessment of the minimum numbers of lines needed Abstract. Induced pluripotent stem cells (iPSCs) are widely used to model human genetic diseases. The most common strategy involves collecting cells from r

Studying rare diseases with #iPSCs often means limited cells—so what’s the optimal sample size for reliable data?

@ashokdinasarapu.bsky.social et al. from Emory & @radboudumc.bsky.social used #RNAseq to find out using Lesch-Nyhan patient samples.

academic.oup.com/stcltm/artic...

🧪 #RareDisease

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Trailhead Biosystems Launches Innovative Hematopoietic Progenitor Cells from iPSCs Trailhead Biosystems unveils TrailBio® Hematopoietic Progenitor Cells, offering researchers a consistent and scalable model for hematopoietic research.

Trailhead Biosystems Launches Innovative Hematopoietic Progenitor Cells from iPSCs #USA #Trailhead_Biosystems #Beachwood #Hematopoietic_Progenitor_Cells #iPSCs

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