Age differences in endocannabinoid tone are ameliorated after recent cannabis use - Scientific Reports Scientific Reports - Age differences in endocannabinoid tone are ameliorated after recent cannabis use

Study assayed levels of seven #endocannabinoids in sample of adults. At baseline, older adults exhibited lower AEA & DEA than younger adults & lower LEA than midlife adults. Findings indicate broad endocannabinoid elevations after #cannabis use regardless of age. www.nature.com/articles/s41...

Development of #cannabinoid-based therapies for #Parkinsons disease: emphasis on targeting cannabinoid receptors as CB2, PPAR-γ and GPR55 receptors

Sonia Burgaz, Santiago Rodríguez-Carreiro...Javier Fernández-Ruiz #endocannabinoids

link.springer.com/article/10.1...

Distinct endocannabinoids specifically signal to astrocytes or neurons in the adult mouse hippocampus - Nature Neuroscience Distinct endocannabinoids signal to either astrocytes or neurons, evoking contrasting regulation of synaptic function. This works reveals the high degree of complexity of neuronal and astrocytic signa...

Distinct #endocannabinoids specifically signal to #astrocytes or #neurons in the adult #mouse #hippocampus
doi.org/10.1038/s415...

🚨 Must-watch: Dr. Steve Mahler on how cannabinoids shape motivation, reward, and craving—and why it matters for addiction science.

🎥 www.youtube.com/watch?v=9ImB...

@uci_cannabis

#Neuroscience #AddictionResearch #Endocannabinoids

🌟... #functionalgenomics @fg-pgc.bsky.social travels from Germany to Toronto, Canada, @utoronto.ca where Dr PAVEL POWLOWSKI recently obtained his PhD👨‍🎓and studies #genes #endocannabinoids and human cells in a dish #iPSCs in #bipolardisorder. 🧬🧠

🧬 New study finds cell-type specific regulation of the endocannabinoid system in the endometrium, with higher FAAH in epithelial cells and changes across the menstrual cycle—offering insights into reproductive biology.
🔗 doi.org/10.1089/can....

#Endocannabinoids #Endometriosis

@lcornelas.bsky.social crushing her talk at the 25th National Science Network on Drug Abuse conference at @universityofmiami.bsky.social! Incredible and important work on #GABA, #endocannabinoids, traumatic #stress, and #alcohol use in animal models.

#NSNDA2025 #addictionscience #trauma @unm.edu

Stress reactivity is modulated by cannabinoid type-1 receptors in norepinephrine and epinephrine neurons in a context-dependent manner Disruptions in the endocannabinoid system (ECS) and norepinephrine/epinephrine (NE/E) system are individually linked to stress-related neuropsychiatri…

7/
Grateful to our collaborators and lab team for their insights and dedication.
📄 Read the full study: sciencedirect.com/science/arti...
#Neurobiology #Endocannabinoids #MentalHealth #ScienceThread #Norepinephrine

Unpacking the Runner’s High: Endocannabinoids, Not Endorphins, Drive Euphoria "The runner's high, long attributed to endorphins, is now understood to be primarily driven by the body's natural endocannabinoids."

The Surprising Truth About Runner's High: Why Endorphins Aren't the Full Story

#RunnersHigh #ScienceOfExercise #Endocannabinoids #FactRage #FactRageNews

tglm.us/NEUiR

#Cannabis legalization (medicinal) occurred only a few years after the discovery of the #EndocannabinoidSystem and #endocannabinoids. Information was minimal to the community, much of what was shared is still circulating today. There's so much more to learn, I love #THC, but #CBGa is the way. #Weed

Did you know your body makes its own cannabinoids? 🧠✨
Here are the five known endocannabinoids that help regulate mood, pain, appetite, and more.
Your body is wired for balance—naturally.
#Endocannabinoids #cannakeys #Anandamide #2AG #NoladinEther #Virodhamine #NADA #CannabisScience

Revisión sobre la relación de lo endocannabinoides con la (in)fertilidad masculina, para las amantes de la endocrinología:
www.sciencedirect.com/science/arti...
#bianorbiotech #MaleFertility #endocannabinoids #eCB #ReproductiveEndocrinology

Stop Chasing High THC – Start Chasing ECS Balance
For years now, I've been discussing the importance of what we call ECS Balance. #Cannabinoids #CBD #CBDa #CBG #CBGa #ECSProducts #Endocannabinoids #GenevievesDream #Researcher #ResearcherOG
wmhfarms.com/ecs-balance-...

Meet TRPV1 – Your Body’s “Chili Pepper” Pain Sensor: If you've ever bitten into a hot chili and felt that flaming burn, you've met TRPV1. #Cannabinoids #CBD #CBGa #ECSBalance #Endocannabinoids #Inflammation #Pain #ResearchReview #Researcher #ResearcherOG
wmhfarms.com/when-antidep...

 Metabolic disorders such as obesity, diabetes, and cardiovascular disease represent some of the most critical global health challenges of our time. #Cannabinoids #CBD #CBDa #CBG #CBGa #ECS #ECSBalance #Endocannabinoids #GenevievesDream #ResearchReview #Researcher
wmhfarms.com/capsaicinoid...

Exciting research on how to preserve endocannabinoids in human donor breast milk: "The human milk endocannabinoidome is preserved by high hydrostatic pressure processing but altered by holder pasteurization" Published March 11, 2025: #BabiesDrinkCannabinoids #Cannabis #Weed #EndoCannabinoids #ECS

We've waited five years to see Genevieve's brand launch in partnership with a Dream Farm operation—our family is excited. #Cannabinoids #CBD #CBDa #CBG #CBGa #ECS #ECSBalance #Endocannabinoids #GenevievesDream #Researcher
wmhfarms.com/genevieves-d...

Remember this -we’re approaching the 50% mark, meaning that every other person will be diagnosed in their lifetime. It’s been 4 years since the Stat that 40% of us could get Cancer. The best bet is to treat it before it’s diagnosed; I use #Nature. #CannabisMyMedicine #ECS #Endocannabinoids #THC #CBG

Can Cannabis Provide Some Relief From Chronic Pain The Fresh Toast - For those who suffer, it can be life altering in a negative way. But can cannabis provide some relief from chronic pain?

"Research indicates cannabinoids may reduce pain severity by 30–50% compared to placebo, particularly in neuropathic and inflammatory conditions."
#MedicalMarijuana #MedicalCannabis #Marijuana #Cannabis #Pain #ChronicPain #Cannabinoids #PainRelief #Neuropathic #Inflammatory #Endocannabinoids

“Hope lies in dreams, in imagination, and in the courage of those who dare to make dreams into reality.” -Jonas Salk
#CancerWarrior #Cannabis #CBGa #ECS #Endocannabinoids #Cannabinoids #NatureHeals #Researcher #Hemp #GenevievesDream #CBD #THC #StayPositive

Feeling Blissed After a Yoga Session? The Reason May Lie Within the Body’s Endocannabinoid System That high you can get from yoga may come from endocannabinoids — substances naturally produced by the body that are chemically similar to active compounds in cannabis (marijuana).Studies have shown th...

A source asked me for a copy of a piece on yoga and the endocannabinoid system years ago. Given the current state of the world, I thought it might be helpful for some. #bliss #endocannabinoids #yoga (This piece was republished - original publisher removed it.) www.pranatalent.com/post/feeling...

Eleven clinical trials that will shape medicine in 2025 Nature Medicine - Nature Medicine asks leading researchers to name their top clinical trial for 2025, from gene therapies for prion disease and sickle-cell disease to digital tools for cancer and...

Excited to be part of STEP (#CBD in #psychosis) trials highlighted on the list of 11 trials to watch in 2025 by Nature Medicine
rdcu.be/d4b9O
as leader of peripheral #biomarkers WP, and also doing #metabolomics / #lipidomics / #endocannabinoids etc.
Finally starting in 2025
#proteomics #multiomics

Inbox | Substack

Attention-Worthy Links for December 17th, 2024

bit.ly/awl121724

#warming #global #accelerating #Copernicus #ACES #bridges. #barracks #barriers #culverts #3D-Print #concrete #vaults #pre-eclampsia #mRNA #VEGF #Endocannabinoids #ABHD6 #hippocampus #waves #spindles #ripples #dementia #Alzheimer's

Impact of recreational and medicinal marijuana on surgical patients: A review As medicinal and recreational marijuana use broadens across the United States, knowledge of its effects on the body will become increasingly important…

Of particular importance to the surgeon may be their effects on prolonging intestinal motility, decreasing inflammation, increasing hunger, mitigating pain, and reducing nausea and vomiting. #Endocannabinoids #EndocannabinoidSystem #harmreduction

Very proud that our article on the reduction of #endocannabinoids in #anorexia is featured in the journal of the Swiss National Foundation. Congratulations to Mayron Picolo 👏👏👏 #cannabis @MayronPicolo @lettresunifr @lettresunifr @snf_ch

onlinelibrary.wiley.com/doi/10.1002/er…

Our article on #endocannabinoids in #acute and #weight-recovered #anorexia by #Mayron Picolo is now published @Wiley@MayronPicolo @unifr

onlinelibrary.wiley.com/doi/full/10.10…

Altered circulating endocannabinoids in anorexia nervosa during acute and weight‐restored phases: A pilot study Anorexia nervosa (AN) is an eating disorder characterized by a low food intake and often exceeding exercise, leading to a particularly low body × weight proportion. Patients with AN usually report le...

Our publication on Altered circulating #endocannabinoids in #anorexia nervosa during acute and weight-restored phases just got published in #European #Eating Disorders Review. Check it out at@unifr @Psychologiecli1 @MayronPicolo

onlinelibrary.wiley.com/doi/full/10.10…

IReach Lab on Instagram: "If you want to know more about the role of #endocannabinoids# in #eating #behavior, and in #eating disorders, check Mayron Picolo’s newly accepted paper @https://www.researchgate.net/publication/336530621_Altered_circulating_endocannabinoids_in_anorexia_nervosa_during_acute_and_weight-_restored_phases_-a_pilot_study" 9 likes, 2 comments - psychologiecliniqueetsante on October 27, 2019: "If you want to know more about the role of #endocannabinoids# in #eating #behavior, and in #eating disorders, check Mayron Picolo’s newly accepted paper @https://www.researchgate.net/publication/336530621_Altered_circulating_endocannabinoids_in_anorexia_nervosa_during_acute_and_weight-_restored_phases_-a_pilot_study".

If you want to know more about the role of #endocannabinoids# in #eating #behavior, and in #eating disorders, check Mayron Picolo’s newly accepted paper…

instagram.com/p/B4IWE9Og-vk/…

(PDF) Altered circulating endocannabinoids in anorexia nervosa during acute and weight- restored phases -a pilot study PDF | Anorexia nervosa (AN) is an eating disorder characterized by a low food-intake and often exceeding exercise, leading to a particularly low body x... | Find, read and cite all the research you need on ResearchGate

#endocannabinoids are involved in the regulation of #eating #behavior and potentially dysregulated in #anorexia nervosa. See a preprint by @MayronPicolo in European Eating Disorder Review ⁦@Psychologiecli1⁩

researchgate.net/publication/33…