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Well Avi is #inducted to our #team with this good #pMHC #monomer prep with a little help from Julia

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Science | AAAS

Programmable cellular protein factories | Science www.science.org/doi/10.1126/...

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Science | AAAS

B lymphocyte protein factories produced by hematopoietic stem cell gene editing | Science www.science.org/doi/10.1126/...

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How did COVID mRNA vaccines improve favorable responses and patient outcomes for cancer immunotherapy?
www.nature.com/articles/s41...
A new report today on the priming of CD8+ T cells by these vaccines, a likely explanation
www.nature.com/articles/s41...

6 days ago 138 46 2 0

Here is that #paper @Nature #mRNA #vaccines engage unconventional pathways in #CD8+ #Tcell #priming #KenMurphy #SuinJo #ChandraniThakur @WashUNeurology @washumedicine www.nature.com/articles/s41...

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It's #Wednesday -I am so excited to see a collaborative paper coming out as print 11AM. Its a privilege to have contributed a tiny part along with senior author who has written #immunology #textbook!

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NSF announces 2026 Graduate Research Fellowship Program award offers The U.S. National Science Foundation (NSF) today announced that it has made offers and will award 2,500 Graduate Research Fellowships for the 2026-2027 academic year...

What a #fantastic day for #science and #young #minds -this is such a #great #news www.nsf.gov/news/nsf-ann...

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isnt that scary and sad at the same time!

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As the deadline approaching for our #offered #prospective #graduate #students to #accept our #offer -I cant explain how thrilled I am to welcome them! I know many of them accepted and they are exceptional

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Trump administration drops court fight to cap NIH payments for research overhead costs The Trump administration will not be asking the Supreme Court to take up its fight to slash NIH support for research indirect costs

www.statnews.com/2026/04/08/t...

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Thank you to @HCneuro for awarding our lab a #2025 #pilot #award to examine the role of #adaptive #immune #system in #Parkinson #Disease @WashUNeurology hopecenter.wustl.edu/funding-awar...

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Neuroinflammation in Health and Disease | Keystone Symposia Join us at the Keystone Symposia on Neuroinflammation in Health and Disease, June 2026, in Whistler, with field leaders!

Proud to be attending #Neuroinflammation in Health & Disease, this June in Whistler with @keystoneSymposia.bsky.social Looking forward to big ideas, bold science, and great conversations. keysym.us/KSNeuroInflam26 #KSNeuroInflam26

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Hoping all are #happy and #well #fed #our #team

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See you at the #AAIC2026 as it will be my first AD #conference presenting our work on #Adaptive #immunity #Tcells in #Alzheimer #disease @alzheimerssoc.bsky.social

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Made it to THE #BRIDGE

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Driving towards Edmund Pettus Bridge, #SELMA…the #heart is #heavy #martinlutherking #freedom #johnlewis

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It’s hard to leave this place…..but

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what the #sun #sand #water does to #mind is simply amazing

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Here is the preprint Combined talimogene laherparepvec and binimetinib in patients with NRAS-mutated melanoma induces anti-tumor immunity www.medrxiv.org/content/10.6...

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we believe that the #striking #clinical #responses compel us to report these results so that other patients might benefit from our experience

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we observed unexpected responses in melanoma patients with driver mutations in HRAS, NF1, and GNAQ, indicating that exceptional responses to combined T-VEC and binimetinib may extend beyond NRAS-mutated melanoma.

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#Intratumoral #CD4Tcells following combination therapy were enriched for a CXCR6+ Th1 effector subset distinct from the follicular helper (Tfh) phenotype associated with tumor-reactive CD4+ T cells

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6 of 7 patients (85.7%) who received #TVEC and binimetinib therapy achieved a complete response compared to 2 of 7 (28.6%) patients with NRAS-mutated melanoma treated with T-VEC alone or combined with #checkpoint blockade agents

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we find that #TVEC combined with #MEK #inhibitor #binimetinib induced exceptional clinical responses by amplification of pre-existing #Tcell responses and induction of de novo tumor-reactive immunity.

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This will soon be online as #preprint. Collaboratively, our first attempt to understand #tumor #response upon #oncolytic #virus #TVEC #therapy in #melanoma by a brilliant student in our lab

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Bioinformatics Specialist I - Brown Lab Primary Work Address: 1275 York Avenue, New York, NY, 10021 Current HHMI Employees, click here to apply via your Workday account. About the Lab The Brown Laboratory studies how the tissue microenviron...

We are hiring! The Brown Lab is looking for a computational biologist to join our team.
If you enjoy working with single-cell and spatial genomics data and want to study how immune cells develop and function, we’d love to hear from you!

Apply here:

hhmi.wd1.myworkdayjobs.com/External/job...

1 month ago 6 5 0 0
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Immunological knowledge - Nature Immunology What is the nature of the knowledge sought by immunology research? In this Comment, we discuss what we are collectively aiming to achieve, beyond accumulating packets of information, and how AI-driven...

" #Immunological #knowledge" In parallel to overweight articles, Twitter and Bluesky-type publishing has appeared: short announcements that highlight a finding or advertise an article. Does this add to information overload? www.nature.com/articles/s41...

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Despite delays, NIH grants generated a 250% return on $36.6B investment in 2025: report Funding from the National Institutes of Health (NIH) generated $94.15 billion in economic activity and supported 390,863 jobs in 2025, according to a

Imagine how much #revenue could have been #generated if there were no #funding #delays at #NIH www.fiercebiotech.com/research/des...

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#Preprint #alert " we define developmentally programmed differences in #Tfh #differentiation and function with implications for #pediatric #vaccine #design" www.biorxiv.org/content/10.6...

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I will be in #London from July 12-18 if anyone wants to talk about #TCRs I am all yours! @ox.ac.uk @dunnschool.bsky.social #UCL @britsocimm.bsky.social

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