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Posts by Sanford Stem Cell Institute UC San Diego

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Looking for a quick pick-me-up? 😄 Check out this 20-min episode of the Cell & Gene podcast. 🧬 It features SSCI Director Catriona Jamieson, MD, PhD, who discusses exciting advancements in #cancer treatment that she believes will be available in 1-2 years: bit.ly/4vI2t5h

1 day ago 0 0 0 0
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SSCI Director Catriona Jamieson, MD, PhD, & Alysson Muotri, PhD, director of our ISSCOR Center, are featured in this article about the innovative #space research being performed at @ucsandiego.bsky.social: bit.ly/3On9tUi. @ucsdmedschool.bsky.social @scrippsocean.bsky.social

1 week ago 2 1 0 0
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🔬 SSCI's computational biologist Ludmil Alexandrov, PhD, recently discovered that some E. coli infections lead to genetic mutations often found in early-onset colorectal cancers. 🦠 He's creating a stool-based test to ID young people at high risk. More: bit.ly/4t5qD86. 👏 @ucsdmedschool.bsky.social

1 week ago 2 0 1 0
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Our Karen Christman, PhD, a visiting fellow of the Charité Foundation at @mdc-berlin.bsky.social, will spend three months this summer in Berlin, Germany, partnering with its researchers. Read more about her pioneering work in biomaterials: bit.ly/48hLD32. H/t @christmanlab.bsky.social

2 weeks ago 0 0 0 0
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🚀 Our Integrated Space Stem Cell Orbital Research Center has sent 18 sets of experiments to the International Space Station so far. 🛰️ Why perform research in #space? Director Catriona Jamieson, MD, PhD, explains in an essay in @thelancetoncol.bsky.social: bit.ly/4bVBN9n. 👩‍🚀 @ucsdmedschool.bsky.social

2 weeks ago 1 1 0 0
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Novel Therapeutics and Discoveries | Leo D. Wang, MD, PhD Our conversation with Leo D. Wang, MD, PhD, includes unique insights into novel discoveries and therapeutics for HIV, diabetes, cancer and other conditions. As the director of the City of Hope Alpha Clinic, we discuss the innovative and collaborative nature of the California Institute for Regenerative Medicine (CIRM) Alpha Clinic network. The City of Hope was the first of now nine CIRM Alpha Clinics, designed to improve patient access to stem cell and regenerative medicine clinical trials for all Californians. Leo Wang also serves as an associate professor in the Departments of Pediatrics and Immuno-Oncology, and the division chief of cell, gene, and transplantation therapy at City of Hope, a cancer hospital located outside of Los Angeles, CA, with additional affiliate locations. He leads a research lab dedicated to reprogramming the immune system to fight childhood cancers, where his team works to modify the body’s own immune cells to target and destroy cancer cells. Additionally, his lab studies how these engineered cellular therapies interact with tumors and the native immune system. Wang also oversees clinical trials that use these “living medicines” to treat pediatric brain tumors and other aggressive cancers. Hosted by Bobby Gordon, MA, MBA This episode was recorded on Oct. 17, 2025, and information is current as of the time of this recording. Find more episodes: https://stemcellpodcast.org

bit.ly/3NO9OiN 🎙️ Tune in to our reGEN Podcast with
Leo D. Wang, MD, PhD - City of Hope - for insights on the
@cirmnews.bsky.social Alpha Clinic network & breakthroughs in pediatric #cancer; from engineered cell therapies to “living medicines,” advancing care for aggressive cancers. #stemcells

2 weeks ago 1 0 0 0
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🚀 March 6 was a busy day for us, as our Catriona Jamieson, MD, PhD, chaired a daylong RNA, stem cell- & gene-based therapies track at Precision Medicine World Conference, bringing a space-health perspective. Joining her: Alexis Komor, PhD; @geneyeo.bsky.social; & Alysson Muotri, PhD. bit.ly/4sKgSw1

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🎉 We’re celebrating Maya Gosztyla, PhD, a '24 @ucsdhealth.bsky.social grad and finalist for the Chancellor’s Innovation Award in the student/alumni innovator of the year category for founding BrainStorm Therapeutics. 🥳 She got her start in the lab of SSCI's @geneyeo.bsky.social. bit.ly/4maLKmU

3 weeks ago 0 0 0 0
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Medical Resilience in Space | Dana Levin, MD, MPH Dana Levin, MD, MPH, serves as the director of space medicine for Vast. As the International Space Station plans for decommission in 2030, Vast is an industry pioneer with developing the first commercial space station, Haven-1, for long-term human habitation of low-Earth orbit. We discuss the implications of humans inhabiting space in this new frontier of opportunities, challenges, questions and implications for human health and medicine. Dana’s background before his role at Vast includes working for NASA as a clinical scientist for the human research program, developing methods to assess medical risk for deep space missions and designing medical systems to mitigate them. He was also the clinical lead for NASA’s artificial intelligence clinical decision support task force. Hosted by Bobby Gordon, MA, MBA This episode was recorded on Oct. 17, 2025, and information is current as of the time of this recording. Note, since recording, Vast has released a new launch timeline of 2027 for Haven-1.

bit.ly/4dCaVwg 🎧 Watch or listen to our latest reGEN podcast interview with Dana Levin, MD, MPH, Vast's director of space medicine, as we discuss medical resilience for astronauts living and working in space for extended periods of time. Watch on YouTube or listen where you find your podcasts.

3 weeks ago 0 0 0 0
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🚀 Thanks to all who joined us for our 4th Global Astrobiotech Hub event earlier this month, where we celebrated 18 launches of research projects to the International Space Station — and counting! Read more about the event: bit.ly/4lVOd4j. #stemcellscience #regenerativemedicine #spacemedicine

3 weeks ago 2 1 0 0
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🎉 SSCI directors had a blast sharing their work at @sxsw.com last week. Alysson Muotri, PhD, presented on diversity, Neanderthal DNA & the dark genome. And @geneyeo.bsky.social, PhD, & Alexis Komor, PhD, discussed how #AI is ushering in an era of precision #genetics. 🧬 See you next year in Austin! 🤞

4 weeks ago 2 0 0 0
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SSCI’s Alexis Komor, PhD, and colleagues created an improved version of a gene base editor with higher efficiency minimizing unwanted bystander edits - enhancing 🧬 gene editing & disease modeling for treating genetic disorders. Learn more @ bit.ly/4sms8hU. @natbiotech.nature.com

1 month ago 1 2 0 0
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Nearly 40% of Americans have metabolic syndrome, which carries w/it the risk of liver fibrosis (MASH). Treatment options are limited but expanding, thanks to the work of SSCI's Tatiana Kisseleva, MD, PhD; Gene Yeo, PhD; & colleagues. More on their work: bit.ly/4bsWDvs. H/t @sbpdiscovery.bsky.social

1 month ago 1 0 0 0
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How will AI reshape public health and decision-making? In our latest 🎙️ podcast, @bruceylee.bsky.social, MD, MBA, shares insights on the intersection of AI, systems modeling and health communication systems. 🎧 Watch here: bit.ly/4sDUAeI #AI #Health #StemCells

1 month ago 1 1 0 0
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🎉 A patient with Pitt-Hopkins syndrome has received an investigational, 1st-in-human gene therapy, thanks to the lab of SSCI's Alysson Muotri, PhD. It's the first drug developed using brain organoids — and not animal models — to reach clinical trial. Cheers to hope! 🥂 H/t @ucsdmedschool.bsky.social

1 month ago 3 1 1 0
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💡 Sanford Stem Cell Innovation Center Deputy Director Alexis Komor, PhD, was honored Friday w/the Precision Medicine World Conference Luminary Award for co-inventing #CRISPR base editing. 🌟 SSCI Director Catriona Jamieson, MD, PhD, received the award in 2024, for advancing cancer-stem-cell biology.

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SSCI Director Catriona Jamieson, MD, PhD, recently attended the @ucsdmedschool.bsky.social Summer Research Symposium to support a med student she mentored. “It’s essential for students to conduct research, particularly medical students who will someday see patients,” she said: bit.ly/4rjKDCd #cancer

1 month ago 3 1 0 0
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Team Led by UC San Diego Researchers Selected for Prestigious Global Cancer Prize With up to $25 million from Cancer Grand Challenges, an international team led by UC San Diego professor Ludmil Alexandrov will unlock the secrets of DNA's

Congratulations to SSCI’s Ludmil Alexandrov, PhD, who will lead Team CAUSE, awarded $25M from Cancer Grand Challenges, to decode mutational 🧬 DNA signatures or “fingerprints” that may reveal how cancer begins, informing potential treatments. 🔬 Learn more bit.ly/4r7if63. #Cancer #StemCells #DNA

1 month ago 5 2 2 1
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🦓 This #RareDiseaseDay, we’re proud to shine the spotlight on 5 rare disorders & 4 researchers turning hope into reality for patients w/CPS1D, T-cell acute lymphoblastic leukemia, Rett syndrome, Pitt-Hopkins syndrome & ALS. More: bit.ly/3N8UqNk. H/t @rarediseaseday.bsky.social @nucdf.bsky.social

1 month ago 2 0 0 0
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🚀 Catch up on the latest advances in #space related #stemcell #science and #regenerativemedicine at our Global Astrobiotechnology Hub event THIS MONDAY, March 2, 2-6 p.m. PT. Complimentary online tix are still available at bit.ly/4bhqpol. 🧫

1 month ago 0 0 0 0
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🚀 Just dropped, our new podcast 🎙️ with Alysson Muotri, PhD. We explore the intersection of #stemcells, medicinal Amazon Rainforest discoveries, Neanderthal DNA, space-based research and disease remodeling - all reshaping how we understand human health. 🧬 Watch here bit.ly/46tGJiF 🎧

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🔬 #genetherapy holds incredible promise but carries the risks of immune response and toxicity. To combat this, SSCI's Alexis Komor, PhD, and team developed a workflow that allows scientists to more effectively deliver less DNA. Read more at bit.ly/46d1f72. H/t @natureportfolio.nature.com 🧬

1 month ago 0 0 0 0
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🚀 Catch up on the latest advances in #space related #stemcell #science and #regenerativemedicine at our Global Astrobiotechnology Hub Event on Monday, March 2, 2-6 p.m. PT. Complimentary online tix are still available at bit.ly/4bhqpol. 🧫

1 month ago 0 0 0 0
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💔 The heart’s ability to heal itself is limited. After a heart attack, scar tissue prevents a fatal rupture. But it can't contract or conduct electrical signals, significantly raising the risk of heart failure. More on an innovative solution from SSCI’s Karen Christman, PhD, here: bit.ly/3MMwuze. 💓

2 months ago 0 0 0 0
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SSCI’s @geneyeo.bsky.social and collaborators developed Ribo-STAMP, a technology that tracks protein production in single brain cells. Their @nature.com study maps the brain’s “translatome,” revealing differences in memory neurons & new clues to disorders like autism. Learn more @ bit.ly/3MkKQ9X

2 months ago 0 0 0 0
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Can the hivemind use Carol's frozen eggs to assimilate her? Our @signerlab.bsky.social separates stem cell fact from fiction in the remarkably plausible Apple TV blockbuster Pluribus. bit.ly/4rUc1az H/t @ucsandiego.bsky.social

2 months ago 1 0 0 0
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Stem Cell Biology Industry Trends | Tiffani Manolis This episode features our conversation with Tiffani Manolis, vice president and general manager of the cell biology business at Thermo Fisher Scientific. Our discussion highlights her passion for cell biology and innovative trends in the gene and cell therapy industry, with a focus on advancing technologies that support the development of life-changing therapeutics. Tiffani is an experienced leader in the life sciences industry in her current role and joined Thermo Fisher Scientific in 2022 to lead the cell culture and cell therapy business. Prior to this role, Tiffani held various leadership positions at Agilent Technologies from 2015 to 2022, including vice president and general manager, and associate vice president of marketing for the chemistries division. Tiffani's career also includes significant roles at Bio-Rad Laboratories and USA Scientific. Hosted by Bobby Gordon, MA, MBA This episode was recorded on Oct. 16, 2025, and information presented is current as of this date.

Tune in to learn about innovative stem cell biology trends in our latest reGEN Podcast 🎙️ conversation with Tiffani Manolis from @thermofishersci.bsky.social. Watch here bit.ly/3MApmFZ or listen where you find your podcasts.

2 months ago 0 0 0 0
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RNA and Stem Cell Innovations | Gene Yeo, PhD, MBA Our conversation with Gene Yeo, PhD, MBA, features a deep dive into his innovative work with RNA, gene editing and intersection of stem cells and regenerative medicine. We discuss what’s on the horizon for discoveries and industry-based opportunities. Yeo serves as the director of the Sanford Stem Cell Innovation Center with the goal to facilitate industry growth by leveraging research findings and developed technologies to support the commercialization of applications through strategic collaboration with industry partners. Yeo’s work focuses on high-throughput genomics, systems biology approaches, engineering, and statistical and machine learning methods, as well as biochemical, molecular, and stem cell biology techniques, to solve problems in RNA processing. Hosted by Bobby Gordon, MA, MBA. This episode was recorded on Sept. 22, 2025, and all information is current as of the date of recording.

bit.ly/3M54NRS Learn about innovative and groundbreaking research with RNA, gene editing and stem cells in our latest reGEN Podcast conversation featuring @geneyeo.bsky.social, PhD, MBA. Watch here or listen where you find your podcasts. #stemcells #RNA #sciencepodcast

2 months ago 1 1 0 0
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A Closer Look at...Stem Cells and Human Longevity Can we live not only longer but healthier lives? Robert A.J. Signer and Shiri Gur-Cohen explore how stem cell research may unlock the secrets of longevity. Signer discusses the critical role stem cells play in combating aging-related diseases, such as cancer and immune system decline, by boosting their regenerative abilities. His work on hematopoietic stem cells and “super stem cells,” which better manage cellular waste, shows promise for delaying aging and preventing disease. Dr. Shiri Gur-Cohen examines how vascular and lymphatic systems support stem cell health, revealing new strategies for enhancing longevity and reversing the effects of aging. Don’t miss this in-depth look at the future of aging and human health. [8/2024] [Show ID: 39869] Donate to UCTV to support informative & inspiring programming: https://www.uctv.tv/donate Please Note: Knowledge about health and medicine is constantly evolving. This information may become out of date. More videos from: A Closer Look (https://www.uctv.tv/closer-look) More from: Stem Cell Channel (https://www.uctv.tv/stem-cell) Explore More Health & Medicine on UCTV (https://www.uctv.tv/health) UCTV features the latest in health and medicine from University of California medical schools. Find the information you need on cancer, transplantation, obesity, disease and much more. Explore More Science & Technology on UCTV (https://www.uctv.tv/science) Science and technology continue to change our lives. University of California scientists are tackling the important questions like climate change, evolution, oceanography, neuroscience and the potential of stem cells. UCTV is the broadcast and online media platform of the University of California, featuring programming from its ten campuses, three national labs and affiliated research institutions. UCTV explores a broad spectrum of subjects for a general audience, including science, health and medicine, public affairs, humanities, arts and music, business, education, and agriculture. Launched in January 2000, UCTV embraces the core missions of the University of California -- teaching, research, and public service – by providing quality, in-depth television far beyond the campus borders to inquisitive viewers around the world. (https://www.uctv.tv) 00:00 Start 00:23 Dr. Robert Signer 01:52 Looking For The Fountain Of Youth 06:40 Blood Forming Stem Cells 10:21 Proteins 17:39 Secret to Longevity 20:58 Dr. Shiri Gur-Cohen 25:36 Skin 29:10 Hair Follicles 33:08 Is The Vascular System the Key? 41:08 Tricking Old Stem Cells 45:51 The Fountain of Youth in the Vascular System? 47:28 Questions and Answers

🧫 Can stem cell research unlock the secrets to living longer + healthier? 📺 Watch “A Closer Look at Stem Cells and Human Longevity” w/our @signerlab.bsky.social + Shiri Gur-Cohen on UCTV to find out — a must-watch for 2026, according to the channel. Video @ bit.ly/49mrgCQ; list @ bit.ly/45hBj9U.

3 months ago 0 0 0 0
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Stem Cell Clinical Trials: Behind the Scenes with Julissa Gonzalez at UC San Diego This episode features our conversation with Julissa Gonzalez, MS, who serves as the clinical research data manager at the UC San Diego Sanford Stem Cell Clinical Center. Her work helps frame and prepare insights into stem cell-related clinical trials. Our discussion explores information the public may not readily know about preparing for and administering therapeutics via clinical trials, including unique perspectives on validation, analyses, and patient care outcomes. Hosted by Bobby Gordon, MA, MBA. This episode was recorded on June 2, 2025, and information is current as of the date of this recording.

Get a behind the scenes look at stem cell and related clinical trials at our @cirmnews.bsky.social Alpha Clinic and Sanford Stem Cell Clinical Center with Julissa Gonzalez, MS, in our latest reGEN Podcast episode. View here or listen where you find your podcasts: bit.ly/49y2EY1

3 months ago 1 1 0 0