Fue un lujo poder explicar al cineasta Oliver Laxe la magia que rodea a La Térmica Cultural del @miteco.gob.es .
Una antigua central ahora colonizada por árboles y plantas. Esta simbiosis entre industria y naturaleza nos recuerda que sin vegetación no es posible la vida humana en la Tierra.
Event image card: Human Development: Stem Cells, Models, Embryos Date: 7 – 9 September 2026 Location: University of Warwick, UK
One month until early-bird deadline for @dev-journal.bsky.social & @wellcometrust.bsky.social-funded consortium HDBI's 2026 Meeting on Human Development: Stem Cells, Models, Embryos. Check out the programme biologists.com/meetings/dev... and register by 8 May www.biologists.com/meetings/dev...
I posted on LinkedIn about my reflections on the genome, 25 years on. www.linkedin.com/posts/ewan-b...
📣 New Perspective out in @natcellbio.nature.com! With an interdisciplinary team of scientists, ethicists & lawyer we propose embedded ethics as a framework for navigating the complex ethics of human stem cell–based embryo models.
www.nature.com/articles/s41...
Free full text link: rdcu.be/fckmY
🧵
"Here we present the Human Development Multiomic Atlas, a single-cell atlas of chromatin accessibility and gene expression from 817,740 fetal cells across 12 organs, spanning 203 cell types and more than 1 million candidate cis-regulatory elements"
www.nature.com/articles/s41...
Following several years (!) of discussion and rumination, our team of excellent colleagues - Martin Pera, @nicolasrivron.bsky.social, @amartinezarias.bsky.social, Karen Sermon and Nienke de Graeff - have published a new ethical perspective on SCBEM #embryomodels rdcu.be/fcklG [1/5]
"Hay que mejorar la sanidad pública, la ciencia es la única que puede salvarnos"
El alegato de la activista Noah Higón sobre la importancia de cuidar nuestro sistema sanitario
Out now in @science.org
Pearling drives mitochondrial DNA nucleoid distribution | Science www.science.org/doi/10.1126/...
![Captured by the Artemis II crew during their lunar flyby on April 6, 2026, this image shows the Moon fully eclipsing the Sun. From the crew’s perspective, the Moon appears large enough to completely block the Sun, creating nearly 54 minutes of totality and extending the view far beyond what is possible from Earth. The corona forms a glowing halo around the dark lunar disk, revealing details of the Sun’s outer atmosphere typically hidden by its brightness. Also visible are stars, typically too faint to see when imaging the Moon, but with the Moon in darkness stars are readily imaged. This unique vantage point provides both a striking visual and a valuable opportunity for astronauts to document and describe the corona during humanity’s return to deep space. The faint glow of the nearside of the Moon is visible in this image, having been illuminated by light reflected off the Earth. [alt text from NASA]](https://cdn.bsky.app/img/feed_thumbnail/plain/did:plc:62gdkmpwa7xme36getyqnem3/bafkreicsf2kngfhvnbuq3xv3ywkavmqebetspzequuwsgndbpsknzbmwge)
Captured by the Artemis II crew during their lunar flyby on April 6, 2026, this image shows the Moon fully eclipsing the Sun. From the crew’s perspective, the Moon appears large enough to completely block the Sun, creating nearly 54 minutes of totality and extending the view far beyond what is possible from Earth. The corona forms a glowing halo around the dark lunar disk, revealing details of the Sun’s outer atmosphere typically hidden by its brightness. Also visible are stars, typically too faint to see when imaging the Moon, but with the Moon in darkness stars are readily imaged. This unique vantage point provides both a striking visual and a valuable opportunity for astronauts to document and describe the corona during humanity’s return to deep space. The faint glow of the nearside of the Moon is visible in this image, having been illuminated by light reflected off the Earth. [alt text from NASA]
The #Artemis II astronauts said they needed more superlatives to describe their view of the eclipse, when the Sun was behind the Moon and its near surface was faintly illuminated by Earthshine
![Earthset captured through the Orion spacecraft window at 6:41 p.m. EDT, April 6, 2026, during the Artemis II crew’s flyby of the Moon. A muted blue Earth with bright white clouds sets behind the cratered lunar surface. The dark portion of Earth is experiencing nighttime. On Earth’s day side, swirling clouds are visible over the Australia and Oceania region. In the foreground, Ohm crater has terraced edges and a flat floor interrupted by central peaks. Central peaks form in complex craters when the lunar surface, liquefied on impact, splashes upwards during the crater’s formation.
[alt text from NASA]](https://cdn.bsky.app/img/feed_thumbnail/plain/did:plc:62gdkmpwa7xme36getyqnem3/bafkreid6rp25tpuxaceaziwiduvtsnbystj5s542tlmuhcstyuxyfaj7ve)
Earthset captured through the Orion spacecraft window at 6:41 p.m. EDT, April 6, 2026, during the Artemis II crew’s flyby of the Moon. A muted blue Earth with bright white clouds sets behind the cratered lunar surface. The dark portion of Earth is experiencing nighttime. On Earth’s day side, swirling clouds are visible over the Australia and Oceania region. In the foreground, Ohm crater has terraced edges and a flat floor interrupted by central peaks. Central peaks form in complex craters when the lunar surface, liquefied on impact, splashes upwards during the crater’s formation. [alt text from NASA]
#Artemis II lunar flyby images are showing up! 😍
A crescent Earth setting behind the Moon.
Mitochondria use a shape-shifting process called "pearling" to evenly distribute their DNA, supporting cellular health and offering new insight into mitochondrial genome organization.
Here are a couple of examples. Lung cancer survival rates for EGFR+ mutated Lung cancer.
Our paper is now out in Science! Super excited to share our discovery that #mitochondria #pearling is the elusive mechanism driving the regular distribution and inheritance of #mtDNA nucleoids 🧬 [1/6]
🥳 I am happy to share our latest manuscript published in @natcellbio.nature.com We use #Gastruloids to study #CellCompetition during early mammalian development and find not only that this is highly pronounced in our system but also tightly restricted in time. (1/12) www.nature.com/articles/s41...
The @vbcscitraining.bsky.social is looking a PhD Program Manager! Needless to say this is an incredible important position. So please apply if you want to help us find, recruit and train the next generation of scientists!
RT appreciated!
The Frenster Lab is here! 🍾 I am so excited to start my #EmmyNoether funded group at @uni-freiburg.de this summer. Our group studies #CellCompetition dynamics during embryonic development using #gastruloids from multiple species. Thanks to the @dfg.de for creating this opportunity! FrensterLab.com
Believe it or not: "Primate-specific ZNF808 is essential for pancreatic development in humans". Amazing story.
www.nature.com/articles/s41...
📣 paper alert
We are happy to share our latest work on how HNF1A's involvement in GLI3 processing affects #pancreatic & intestinal #development
5 years of work is 🆕 ONLINE ahead of print 🆕 in @genesdev.bsky.social
I must say I'm really proud of my team! 👏
genesdev.cshlp.org/content/earl...
🧬 New from Johnson et al!
📄Bi-allelic variants in the non-protein-coding minor spliceosome components RNU6ATAC and RNU4ATAC cause syndromic monogenic autoimmune diabetes
Hot off the press! This paper provides protocols for directed differentiation of hPSCs to different pancreatic islet-like endocrine cells as well as to enterochromaffin cells. Congratulations to the whole team! www.nature.com/articles/s41...
RESEARCH |
@ozvanbocher.bsky.social E Zeggini (U Brest, Helmholtz Munich) et al.
The causal links of gene expression and protein abundance on type 2 diabetes risk in 4 ancestries 🧪
MetaScale will create a new community for cutting edge Metabolism research spanning from basic biology to human disease. #Metabolism #research #science #centreofexcellence #centerofexcellence #CoE
We are funded by Research Council of Finland and located at two campuses of Univeristy of Helsinki @helsinki.fi, Faculty of Biological and Environmental Sciences and Faculty of Medicine
We will explore how metabolism is spatially organized across biological scales and how controlled exchange of metabolites links organelles, cells and organs into functionally integrated networks. #metabolism #research
Excited to Kick-off our 8-year Centre of Excellence focusing on Metabolic Integration. MetaScale brings together the groups of @pekka-katajisto.bsky.social @awartiovaara.bsky.social Elina Ikonen, Ville Hietakangas @emmihelle.bsky.social @rafabolism.bsky.social and @diegobalboa.bsky.social
Hyperinsulinema, adiposity weight gain and #obesity Associations vs. causality #insulin www.nature.com/articles/s41...
🚨 Job Alert - Please share! 🙏
Interested in 3D gene regulation in development & evolution? 🤓🧬
💥 Our lab at @cabd-upo-csic.bsky.social is expanding!
We’re recruiting:
✅ PhD students
✅ Postdocs
💻🧪 Experimental or computational backgrounds welcome
👇 Details below
New paper out in Nature Communications:
www.nature.com/articles/s41...
We found >250 metabolic enzymes on chromatin.
Only ~20 had been reported before.
This means hundreds of metabolic enzymes may have unexplored nuclear roles.
An advisory panel to Japan’s health ministry has recommended limited marketing approval for therapies using induced pluripotent stem cells for heart failure and Parkinson’s disease. https://scim.ag/4bj5iBw
Two decades of iPS cell research. By my friend and colleague @gladstoneinst.bsky.social Shinya Yamanaka, in @cp-cellstemcell.bsky.social www.cell.com/cell-stem-ce...
