Rechts oben in der Ecke steht in einer weißen Blase "tonspur Wissen“. Am rechten Bildrand ist ein Foto der Neurowissenschaftlerin Hanna Zwaka. Das Bild der Person ist schwarz-weiß eingefärbt, um die Konturen der Person beschnitten und zusätzlich weiß umrandet. In einer großen weißen Blase, die mittig-links im Bild platziert ist, steht: „Warum müssen wir eigentlich schlafen? Hanna Zwaka, Leibniz-Institut für Neurobiologie“. Der Bildhintergrund ist ein blau-grün eingefärbtes Foto eines Betts mit einem Wecker zu sehen.

Warum müssen wir eigentlich schlafen?
Hanna Zwaka (@hannazwaka.bsky.social) vom Leibniz-Institut für Neurobiologie (@linmd.bsky.social) bei #TonspurWissen, dem #Podcast von @leibniz-gemeinschaft.de & Rheinischer Post.
🛌 👉 pod.fo/e/3ffd3d
#Schlaf #Gesundheit #Gehirn #Schlafmangel #Biologie

A macro photo, side view, of a bright metallic green bee on a yellow, daisy-like flower, against a blue sky background. The bee is carrying a full load of bright yellow pollen.

If you're in need of a bit of color this morning, here's a metallic green sweat bee who wants all the pollen. Anza-Borrego Desert, California.
#Bugsky 🌿🐙🐝🌼

Digital heart replicas can guide a lifesaving procedure The "digital twins" helped doctors spot good targets for heart ablation in 10 patients. Months later, all of them are free of sustained faulty rhythms.

Virtual replicas of individual patients’ hearts have allowed doctors to refine and personalize a lifesaving medical procedure for dangerous rhythm disturbances.

www.sciencenews.org/article/digital-heart-re...

Octopamine regulates neural circuits in the mushroom body and central complex, influencing sleep and arousal. Sleep is a widespread yet incompletely understood phenomenon, and animals exhibit diverse arousal states beyond the simple binary of sleep and wake. Essential behaviors such as feeding, courtship, and...

Excited to share our latest paper from the lab, now out in iScience! 🧠✨

Huge credit to the incredible team whose creativity and hard work made this study possible—so proud of my team! 🙌

#Neuroscience #Sleep #Drosophila #Behavior #Connectomics

www.cell.com/iscience/ful...

Researchers retract multisensory learning paper Even though one set of experiments did not hold up, the authors stand by the original conclusions of the work and plan to resubmit it as a new paper.

The authors of a Nature paper outlining a mechanism for multisensory memories in Drosophila melongaster have retracted the work after they were unable to replicate a set of imaging experiments.

By @callimcflurry.bsky.social

#neuroskyence

www.thetransmitter.org/retraction/r...

Excited to share our work exploring how fly larvae flexibly adjust their foraging decisions based on resource quality and valence, shaped by prior experience 🪰🥳! Check it out: www.biorxiv.org/content/10.6...

🚨🚨 New preprint 🚨🚨
We found that the ovary directly controls protein appetite in Drosophila.
Yes — the ovary doesn’t just make eggs… it tells the fly what to eat!
www.biorxiv.org/content/10.6...
If you want all the details, click above ☝️
If you just want the fun, GIF-guided overview, keep reading 👇

🧵 New preprint led by @bingbrunton.bsky.social, @elliottabe.bsky.social, @lawrencehu.bsky.social

We gave a worm brain control of a fly body and it walked

What did we learn? Nothing, other than deep reinforcement learning is effective

We call it the digital sphinx

www.biorxiv.org/content/10.6...

Sometimes failed experiments reveal gaps in how we are thinking about a problem, and digging into why an experiment didn't work can lead to discovery. This new preprint by Anne Sustar, in collaboration with Dion Dickman's lab, is one of those gratifying instances.🧵

www.biorxiv.org/content/10.6...

How does an animal choose between exploring for a better food source and taking advantage of a known one? Our recent work in Current Biology demonstrates how recent feeding and metabolic state dynamically influence fly local search. bit.ly/3PfrIv3 #Science #Neurosky #Foraging #Drosophila

1/7 🧠 My journey into development begins with this work and question: how does the brain's spatial navigation system develop? We found that the neural networks for spatial navigation (tori and rings) are preconfigured and only later anchor gradually to the world with experience! 🧵

Flies beat their wings more than 200 times per second. How do proprioceptors rapidly sense and fine tune the wingstroke?

@ellenlesser.bsky.social combined genetic tools with the connnectome to create an atlas of Drosophila wing proprioceptors. @elife.bsky.social

elifesciences.org/articles/107...

Single-celled organism with no brain is capable of Pavlovian learning A trumpet-shaped, single-celled organism seems able to predict one thing will follow another, hinting that such associative learning emerged long before multicellular nervous systems

This is an awesome discovery:
A single-celled organism with no brain called Stentor seems capable of Pavlovian learning. Yes, it can actually learn to associate two things despite having no neurons.

My latest for @newscientist.com. 🧪 #science #memory #learning
www.newscientist.com/article/2519...

We are thrilled to offer you a rich and diverse scientific programme during the #GöttingenMeeting2027!

The list of symposia awaiting you is now published in the newest issue of Neuroforum: nwg-info.de/sites/nwg-in...

Recent social experience alters song behavior in Drosophila
#Drosophila

fly circuit diagram

When a fly lands on your arm, how does your nervous system decide where to swat?

By reconstructing tactile axons in a Drosophila connectome, we found a leg somatotopic map and downstream circuits that sample the map to initiate targeted grooming

Led by Leila Elabbady, PhD

doi.org/10.64898/202...

Should biology put complexity first? The dictum “Everything should be made as simple as possible, but no simpler” poses a problem for biology. How simply can it be told without doing dama…

Should biology put complexity first? www.sciencedirect.com/science/arti... - excellent essay by @philipcball.bsky.social. I would add epistasis to polygenicity and pleiotropy as a ubiquitous and fundamental phenomenon, not some optional complication that we can try to account for afterwards

The molecular evolution of vertebrate organs Nature Ecology & Evolution - This Review discusses recent advances in the molecular evolution of vertebrate organs, including rates of evolution of organs and cell types, molecular mechanisms...

Our internal organs are evolutionary marvels. New technologies are transforming our understanding of the evolution of vertebrate organs. You can find more by reading here:
rdcu.be/e5EgU
#EvoBio #EvoDevo 🐟🦎🐢🦇🐊🦜

Time-calibrated phylogeny of the family Drosophilidae showing major species groups, surrounded by representative adult flies that highlight the remarkable morphological diversity of this model insect group. The composite image was created using Microsoft PowerPoint. Fly photographs were taken by Darren J. Obbard and are published under the Creative Commons Attribution License with permission.

The #fly community aims to achieve a comprehensive genomic study of the Drosophilidae family. @pankajd.bsky.social @bernardkim.bsky.social @petrovadmitri.bsky.social @darrenobbard.bsky.social present a comparative gene annotation for 301 #Drosophilidae species @plosbiology.org 🧪 plos.io/4c3pyrI

After decades of debating the “scientific publishing crisis”, the time as come to decide.

This is an English translation of my original German contribution to the Merkur Blog in response to the contributions by Gehring and Tautz. “Scientific publishing” may sound like a minor rung in the ivory […]

How do busy bees avoid overheating from flying? New measurements could help predict pollinators’ ability to withstand climate change

How do busy bees avoid overheating from flying? The breeze that bumble bees generate by flapping their wings stops them from overheating as they hover in place. www.science.org/content/arti... #biology #Entomology #science #SciChat

Using our bee-tracking drone, we discovered that honey bees 🐝 have highly precise and individual routes. Now published at @currentbiology.bsky.social : doi.org/10.1016/j.cu...

Relative value learning in Drosophila melanogaster larvae Abstract. The ability to learn from past experiences to inform future decision making is crucial for humans and animals alike. One question with important

It is not only about "reward" or "punishment" when insects learn. A new study @royalsocietypublishing.org shows that Drosophila larvae learn relative values to a set of odors, i.e., less or more rewarding than other odors. royalsocietypublishing.org/rspb/article...

Identification of an engram ensemble mediating memory forgetting in the dentate gyrus Hu et al. show that the dentate gyrus engram comprises two neuronal ensembles: one supports remembering, and the other promotes forgetting. By shifting the balance between these ensembles via Rac1 sig...

Identification of an engram ensemble mediating memory forgetting in the dentate gyrus www.cell.com/neuron/fullt... - paper claims we make two engrams - one for remembering and one for forgetting! 😮

The first paper from the lab is now out in Science Advances: Multimodal social context modulates larval behavior in Drosophila
www.science.org/doi/10.1126/...
We find that fly larvae keep their distance to conspecifics in the absence of food, enjoy reading! @cbehav.bsky.social @uni-konstanz.de

Neuronal networks in the dorsal hippocampus causally regulate rescue behavior in mice dos Santos Correa et al. show that exposure to a stressful context promotes the acquisition of rescue behavior in mice and that the dorsal hippocampus is required for this learning. Calcium imaging re...

Thrilled to share that our first study on the hippocampus’ role in helping behavior in mice is now published in @cp-cellreports.bsky.social! This work was driven by an amazing team in my lab, and marks an important milestone for more exciting studies to come!
www.cell.com/cell-reports...

Hogwarts Express 💨

Multiple protein structure alignment at scale with FoldMason Protein structure is conserved beyond sequence, making multiple structural alignment (MSTA) essential for analyzing distantly related proteins. Computational prediction methods have vastly extended ou...

FoldMason is out now in @science.org. It generates accurate multiple structure alignments for thousands of protein structures in seconds. Great work by Cameron L. M. Gilchrist and @milot.bsky.social.
📄 www.science.org/doi/10.1126/...
🌐 search.foldseek.com/foldmason
💾 github.com/steineggerla...

Science journals retract 500 papers a month. This is why it matters A small team of volunteers is tracking thousands of falsified studies, including cases of bribery, fraud and plagiarism

‘Science journals retract 500 papers a month. This is why it matters.
A small team of volunteers is tracking thousands of falsified studies, including cases of bribery, fraud and plagiarism’

Ivan Oransky @retractionwatch.com, @alicedreger.bsky.social @thetimes.com

www.thetimes.com/uk/science/a...

How do our senses control movement?
Janelle Pakan @linmd.bsky.social examines how sensory and motor neural circuits in the brain work together. Understanding these processes could revolutionize therapies for movement disorders like Parkinson's.
👉 www.leibniz-gemeinschaft.de/en/research/...