The best way to spark interest in science is by sharing the beauty of microscopy images. I'm excited to see my picture of the intestine featured in the Dutch newspaper 'de Volkskrant'! #microscopy #ScienceArt

Our preprint of Polytope is featured in the ISEH preprint watch

Polytope: High-resolution epitope barcoding for in vivo spatial fate-mapping Tracing the fate of individual cells and their progeny remains a challenging task. While imaging-based fate-mapping provides spatial information, it generally lacks complexity due to limited label div...

Excited to share our preprint: Polytope, an epitope barcoding system, generating up to 512 unique color codes for in vivo lineage tracing. 🌈🧬 This tech enables spatial fate-mapping with unprecedented clonal and spatial resolution! doi.org/10.1101/2024... #SpatialBiology #LineageTracing #Polytope

Holistic genetic barcoding reveals a lineage tree of tissue macrophage development Tissue macrophages are crucial for organ development and homeostasis, yet the developmental routes leading to tissue macrophages remain controversial. By combining unbiased Polylox barcoding with comp...

🎉 Next preprint on its way!
#Polylox #barcoding + computational modelling meets #macrophage #development!

We used 𝐮𝐧𝐛𝐢𝐚𝐬𝐞𝐝 𝐏𝐨𝐥𝐲𝐥𝐨𝐱 𝐛𝐚𝐫𝐜𝐨𝐝𝐢𝐧𝐠 to trace thousands of embryonic progenitor clones and map their development into tissue-specific macrophages.

Happy reading!
doi.org/10.1101/2024...

Many thanks, Larissa!!!

Holistic genetic barcoding reveals a lineage tree of tissue macrophage development https://www.biorxiv.org/content/10.1101/2024.11.29.625985v1 Tissue macrophages are crucial for organ development and homeostasis, yet the developmental routes l

Holistic genetic barcoding reveals a lineage tree of tissue macrophage development www.biorxiv.org/content/10.1101/2024.11....

Polytope: High-resolution epitope barcoding for in vivo spatial fate-mapping https://www.biorxiv.org/content/10.1101/2024.11.20.624484v1 Tracing the fate of individual cells and their progeny remains a challenging task. While imaging-bas

Polytope: High-resolution epitope barcoding for in vivo spatial fate-mapping www.biorxiv.org/content/10.1101/2024.11....