Check out Evelyn's latest work. This is a beautiful story on how Arachidonic Acid regulates neutrophil swarm initiation. Come for the science, stay for the incredibly beautiful figures and movies 🤩
This is the mathematician equivalent of screaming and running around
I'm planning on a GIANT roxygen2 release in the near future (tons of bug fixes, improved R6 support, new S7 support, ...) so if you use for your packages, I'd really appreciate you trying it out and letting me know if you see any problems! github.com/r-lib/roxyge... #rstats
I don’t think solution is adversarial, i think we need to invest, as a society, in checking our work
Standards like Wikipedia would be ideal. But the work of checking work has to be paid, somehow - peer review is not equipped for modern science. No one is actually incentivized to check things this way, and authors aren’t incentivized to facilitate this checking
I think that somewhere in the pipeline we need professionals who are paid, full time, to check datasets, processing pipelines, and statistical analysis. There has to be money for this because what i just described is easily 40+ hours of work for even relatively simple papers.
I agree with what @kawillis.bsky.social is saying here. I think it’s an interesting idea but would need to be engineered carefully. Lots of possible unintended consequences. I like the idea of simple “downvoting” / mechanism for public scrutiny - but financially incentivizing and adjudicating…. ?
Let's say we get past all of this. Now. What do you see as the implications, in the real world where papers have more than one funder, when one of those multiple funders says a paper is "bugged"? What should they be, and what can we predict is likely to happen?
This is a great idea. Gets the individual incentives ($) lined up with the collective incentives (good scientific knowledge) in a viable and sustainable way
Funders, why not?
Article header from the European Journal for Philosophy of Science (2026), labeled “Paper in Philosophy of Science in Practice.” The title, “Pursuitworthiness of breakthrough experiments: transforming emerging intuitions into established norms,” appears in bold above the author Szymon Miłkoś (with ORCID icon).
Unconventional experiments that later redefine what counts as 'pursuitworthy' are excluded by strict standards. Szymon Miłkoś suggests that we need “transformative” standards: judge risky research by how well it turns intuitions into shareable norms 📄👇 link.springer.com/article/10.1... #HPS #philsci
I do not understand how *every* mechanism I review grants for requires me to submit detailed feedback, yet everything I apply to is just like yeeting science into the void.
Grow Flat midbrain organoids (up to 800 μm-thick) onto 3D-printed resin vascular network-mimicking meshed tubes (200 μm interval, 200 μm diameter😎) for 3 months
Almost zero hypoxia, necrotic core, or ER stress
⏫Dopaminergic progenitors/neurons
#CellStemCell 2025
www.cell.com/cell-stem-ce...
Hey, craniofacial and development folks! Check out a new preprint from me and @crumplab.bsky.social about the developing jaw. Here, we show how major signaling pathways establish distinct compartments along the oral-aboral axis. I'm excited to share it with you all!
This essay by @epress.bsky.social does an excellent job
illuminating the wrenching cracks among American Jews. It is a sensitively-woven description, not a political argument--and a reminder to those otherwise inclined that "the Jews" are not, and have been never been, a monolithic lobby group.
Hot off the press 🚨 Epidemic spreading between regions is often modelled on a network 🕸️ But how do we describe this process properly? Here, we show how to build a linear transport operator at the network scale, by coarse-graining local advection-reaction-diffusion within edges. shorturl.at/0tAN8
The world's first view of Earth taken by a spacecraft from the vicinity of the Moon. The photo was transmitted to Earth by the United States Lunar Orbiter I and received at the NASA tracking station at Robledo De Chavela near Madrid, Spain. This crescent of the Earth was photographed August 23, 1966 at 16:35 GMT when the spacecraft was on its 16th orbit and just about to pass behind the Moon. Credit: NASA.
Earthset captured through the Orion spacecraft window at 6:41 p.m. EDT, April 6, 2026, during the Artemis II crew’s flyby of the Moon. A muted blue Earth with bright white clouds sets behind the cratered lunar surface. The dark portion of Earth is experiencing nighttime. On Earth’s day side, swirling clouds are visible over the Australia and Oceania region. In the foreground, Ohm crater has terraced edges and a flat floor interrupted by central peaks—formed when the surface rebounded upward during the impact that created the crater. Image Credit: NASA.
How it started, how it's going
Left: Lunar Orbiter I, 1966
Right: Artemis II, 2026
flic.kr/p/8Grtp2
flic.kr/p/2s68RXM
#Artemis 🧪🔭
"Our findings identify ECM composition and mechanics as a primary mechanism governing mammalian regeneration. By demonstrating that the ECM acts as a mechanochemical signalling hub, we show that “retuning” the physical environment from a stiff, collagenous state to a soft, HA-rich state can.."
Image shows the title of the article, "The time has come for big changes to improve research funding", and the author, Peter Kolarz.
The competitive #researchfunding system is at breaking point. In our new Perspective, Peter Kolarz from @rorinstitute.bsky.social argues for whole system transformation, as innovations to address ongoing problems will not suffice.
🧪 #AcademicSky
plos.io/4mjCi0g
Extrinsic factors can create a local tissue environment that encourages restoration @science.org
www.science.org/doi/10.1126/...
www.science.org/doi/10.1126/...
@canaztekin.bsky.social
www.science.org/doi/10.1126/...
@storerlab.bsky.social @scicambridge.bsky.social @kevinchalut.bsky.social
We have a new story out at @natcomms.nature.com!
This time our lab tackled the enigmatic "autoinflammation of unknown origin". These #autoinflammatory patients don't fit the criteria of classical syndromes. It wasn't even clear they were a single group, to be honest
www.nature.com/articles/s41...
It's been a while... dusted off some old code to see what the current publication lag times are at cell bio journals.
At the end of the post there's the poor paper with the longest delay in the dataset...
Hold On Hope: publication lag times at cell biology journals
quantixed.org/2026/04/09/h...
This is so, so well-articulated.
A Spin-Glass Metabolic Hamiltonian optimized by Quantum Annealing Reveals Thermodynamic Phases of Cancer Metabolism www.biorxiv.org/content/10.64898/2026.04...
" it represents a larger jump in capabilities than most
previous model releases."
"Claude Mythos Preview is significantly more capable than Claude Opus 4.6, the most
capable model discussed in our most recent Risk Report."
www-cdn.anthropic.com/53566bf5440a...
“The researcher found out about this success by receiving an unexpected email from the model while eating a sandwich in a park.”
this is so painful to read, i love it github.com/stephenturne...
Jeff Bezos has $222 billion.
If he paid my wealth tax this year, we could fund insulin in America for everyone who needs it plus free school lunch for every kid in Texas—and have plenty of money left over.
And Bezos would still have $215 billion dollars to spare.
In diseases like Sarcoidosis Granulomas are ubiquitous and mysterious, and RIPE to be demystified by spatial omics analysis.
Kudos @jonas_schupp for this groundbreaking work. Read paper at academic.oup.com/ajrccm/artic...
#CureSarcoidosis
