🔈Paper out! We turned the most fascinating phage host-switch mechanism, diversity-generating retroelements, into a programmable mutagenesis tool, DGRec. You can perform targeted hypermutation of any 50-200bp sequence directly in vivo in E. coli www.nature.com/articles/s41...
Tune in this week to the DinoSphere seminar to hear Rocío Mozo Muñoz (IBE-UPF-CSIC) talk about her work in phylogenomics of Symbiodiniaceae!
📆 16 April - 9AM CEST
🔗 tinyurl.com/5fje3s55
@ehehenberger.bsky.social @manondemulder.bsky.social @chandnibhickta.bsky.social Norico Yamada, Edmée Royen
a simplified evolutionary tree of eukaryotes with pictures of various microbes
New #ISEPpapers #preprint by @deemteam.bsky.social: Re-evaluating the eukaryotic Tree of Life with independent phylogenomic data www.biorxiv.org/content/10.6...
#Protists #Microbes #Evolution #Eukaryotes #TreeOfLife #Phylogeny #Phylogenomics #Bioinformatics #Algae
FAMSA2 is so wicked fast!
10 years after the first FAMSA paper, its successor is now published in Nat Biotech! We believe that FAMSA2 can enable analyses of large protein collections that were previously unattainable. Thank you, Andrzej and Cedric, for great collaboration
www.nature.com/articles/s41...
1/ Excited to share our preprint! 🥳
Degradation of aromatic compounds, including BTEX pollutants, requires highly endergonic aromatic ring reduction. Using #cryoEM and in situ #cryoET, we show how BCRII couples electron bifurcation modules in one giant redox machine
www.biorxiv.org/content/10.6...
Excited to introduce LiftOn – an open-source tool for accurate, scalable liftover of genome annotations (GFF) across assemblies. 🚀
👉 Code & community: github.com/Kuanhao-Chao...
It’s been incredibly rewarding building this for the genomics community. Can’t wait for your feedback and contributions!
One of biggest mysteries in biology: how did complex eukaryotic cells evolve from simple microbes? ~1.8 billion years ago, an archaeal cell likely merged with a bacterium to form the first eukaryotic cell, but can we ever find direct evidence of this transformative event? 🦠 🚶♂️
Very proud to share our new work on General, orders-of-magnitude faster whole-genome analysis with genotype representation graphs (GRG). We topped ourselves in this one 🚀 and made GRG a practical foundation for biobank-scale population and statistical genetics. www.biorxiv.org/content/10.6...
1/ BRAKER4 hatched!
The Earth BioGenome Project is on track to sequence ~1.5M eukaryotic species. Every one needs a structural annotation. No Perl monolith was going to survive that. So we rewrote BRAKER from the ground up. github.com/Gaius-August...
Functional divergence of LhcSR and PsbS in zeaxanthin‐mediated non‐photochemical quenching nph.onlinelibrary.wiley.com/doi/10.1111/... @newphyt.bsky.social
"Postdoctoral Research Associate, Fruit Development at Boyce Thompson Institute for Plant Research, Ithaca, NY, United States"
Read more here: recruiting.paylocity.com/Recruiting/Jobs/Details/...
#PlantSciJobs
"Postdoctoral Position in Plant Developmental Biology at Yunnan University, Kunming, China"
Read more here: arabidopsis.org/news/jobs/view
#PlantSciJobs
With a 135 complete, circular Pelagibacter genomes, we have answered some of the most outstanding questions about what is often considered the most abundant organism on the planet, with roughly 10 million times more individuals in the ocean than stars in the universe. Check out our preprint.
⚠️⚠️
@jacquet-chris.bsky.social and I are organizing the 2nd "non seed plant" French meeting.
As for the one in 2025, the goal is to better structure our emerging community across French institutes.
It will take place in Toulouse, June 24th-25th.
Registration 🔽
nonseedplants26.sciencesconf.org
There is a lot of undescribed prokaryotic diversity in existing whole-genome metagenomic data!
www.nature.com/articles/s41...
Job alert🚨 Postdoc (Computational Proteomics × Plant Immunity) 🌱
Join us to build a cross-species plant pan-terminome & study proteolysis in immunity with excellent collaborators: Bernhard Kuester, Mathias Wilhelm, @degradomics.bsky.social, Patrick Willems, @patrickbryant1.bsky.social
Please RT 🙏
Undaria pinnatifida gametophyte
Our work on chromatin evolution in brown algae is now published in @natecoevo.nature.com! We show that developmentally complex brown algae evolved without epigenetic silencing pathways long thought universal, underscoring why non-model lineages are important to study. www.nature.com/articles/s41...
Scalable homology detection with ERAST | Nature Biotechnology https://www.nature.com/articles/s41587-026-03051-1
Fancy a post-doc to study the variability of of mycorrhizal responses in wheat? jobs.inrae.fr/en/ot-28865
Join the LIPMe !
I'm hiring! I have 2 open positions:
🔬 Postdoc
🧪 Research associate
We study how animal multicellularity evolved by exploring the molecular logic of cell adhesion using cell biology, 'omics, and tool-building in non-model organisms.
Come join us!
Details and application links 👇
Please repost
New evidence suggests oxygen wasn’t the primary culprit behind 300-million-year-old mega-bugs.
The data indicate such bug behemoths could exist today but likely don’t because bats and birds would quickly eat them into extinction.
Let’s celebrate birds.
#Paleontology
🧪🧪
New at @science.org
A snail shaped like long island
Deadline for symposium proposals at the @asn-amnat.bsky.social American Society of Naturalists stand alone meeting on long island due April 30 www.amnat.org/announcement... Plus check out this cool meeting logo of a snail shaped like long island
We are destroying species' habitats, leading to a mass extinction event.
This habitat destruction also reduces the genetic diversity _within_ species.
Our latest work develops quantitative models to predict how much genetic diversity has been and _will be_ lost.
🧬🧪🧵
www.pnas.org/doi/10.1073/...
Our lab is hiring for a Research Assistant position! Please repost widely.
jobs.dayforcehcm.com/en-US/wistar...
I no longer get invited to social gatherings because I keep making people watch Angine de Poitrine's KEXP live show and giving the ▲ greeting. #microtonalfacemelter
How much protein diversity can Life on Earth actually generate?
With DIAMOND DeepClust, we show how billions of proteins across the tree of life can be clustered at low-identity for downstream analytics tasks.
📚Paper: www.nature.com/articles/s41...
💻Code: github.com/bbuchfink/di...
Evidence for the acquisition of a proteorhodopsin-like rhodopsin by a chrysophyte-infecting giant virus www.biorxiv.org/content/10.1...
