๐จWeโre hiring a postdoc! If youโre interested in #ageing #immunology #genomics and #brain_cancer, please apply in the link below!
๐ฌ We study the impact of ageing and genetic variation on the immune microenvironment and therapy responses.
๐
Deadline: 30th April 2026.
www.lih.lu/en/job/?valu...
Posts by Rui Santalla
Photo of all our team members at our international lab dinner, with some of the dishes at the front of the picture
Celebrating our annual international lab dinner ๐ ๐จ๐ฝโ๐ณ ๐ง๐ปโ๐ณ
We are so fortunate to have this amazing team of motivated scientists, and very talented cooks ๐คฉ sharing delicious food & culture from around the world ๐๐๐
Grateful for our #international #team ๐ฎ๐น๐ซ๐ท๐จ๐ฆ๐ช๐ธ๐จ๐ญ๐ฌ๐ง๐ช๐ฌ๐ฉ๐ช๐ต๐น๐ฒ๐ฝ๐ฎ๐ช - this truly enriches our science ๐ ๐
How can we reawaken the bodyโs own anti-viral defenses to fight brain cancer?
Delighted to share our new study where we now answer this question, led by the brilliant @alvarezprado.bsky.social who is now an independent PI at LIH Luxembourg ๐๐
#BrainTIME ๐ง ๐ฆ ๐งช
๐งต
www.sciencedirect.com/science/arti...
๐จ New paper alert! ๐จ Iโm thrilled and proud to share that our latest work has just been published in @science.org! ๐ ๐งฝ
๐ Read our paper here: doi.org/10.1126/sci...
๐ฌ Watch a summary: youtu.be/MttCA3GGWEM
๐งต Or keep reading for the key points! ๐ 1/19
Happy to share that Iโll be starting my lab as a junior group leader at the Georg-Speyer-Haus in Frankfurt in 2026. Weโll study how transcriptional regulators control neutrophil function in cancer. Iโll be hiring soon (PhD/lab tech), please reach out if you know someone interested!
Coming back to the big picture (every time I read about lung cancer): Imagine if we only knew the cause of >75% of cases of the *most* prevalent cancer type globally. We could avoid all that suffering, re-invest that funding into something else. Isn't it time to do something with tobacco?
Beyond the (v cool) paper itself, I am intrigued by a few facts:
- 80% (!!!) of never-smoker lung cancer patients are women. Are the molecular mechanisms driving this susceptibility known?
- First time I read about aristolochic acidโ in which plants is this compound present? What are these used for?
I never thought this was even possible. I have a thousand questions and a few concerns. Fascinating.
Celebrating 2๏ธโฃ0๏ธโฃ years of the Joyce Lab ๐
We had an amazing reunion, bringing together past & present lab members from Lausanne & NYC ๐๏ธ๐ฝ
Huge thanks to everyone who came from around the world, shared science & happy memories and together made this milestone really special ๐
#JoyceLab20 #ProudMentor
Wishing our amazing postdoc @lbejarano.bsky.social continued success and happiness - as she leaves us to start her own lab in Spain ๐๐ฅณ
Leire has been one of the most positive, creative, and kind scientists I've had the privilege to mentor - we shall all miss you so much!
#NewPI ๐คฉ
#ProudMentor ๐
Photo of Anna Gavrilenko and Rui Santalla Mendez, taken outside the Agora Cancer Centre in Lausanne
Congratulations to @annagavrilenko.bsky.social, a wonderful scientist in our lab for successfully defending her master's thesis on brain metastasis & completing her MSc degree with flying colours at @unil.bsky.social ๐คฉ๐
Special thanks also to @ruisantalla.bsky.social her super MSc lab supervisor ๐
Why do brain metastases resist #immunotherapy โ even when the same cancer responds outside the #brain? ๐ง ๐งช๐ฅ
We just published a study diving into this question โฌ
Led by an amazing (former) PhD student in my lab โVladimir Wischnewski ๐
๐งต 1/
@cp-cellreports.bsky.social
www.cell.com/cell-reports...
Itโs just bad news all the time now.
โThereโs going to be a missing age class of researchers that will reverberate for years.โ scim.ag/3ERRLDo
The Trump administration's efforts to slash research funding have US graduate students, postdocs and other early-career scientists fearing for their careers. Some might leave the country -- or abandon research altogether.
https://go.nature.com/43ao2zq
Excited to share a new paper from our lab ๐
We investigate the tumor microenvironment - to reveal factors influencing cancer progression & therapy response ๐ฌ๐งช
So we naturally wanted to ask - does the gut #microbiome influence brain #metastasis ๐ฆ ๐ง ?
Massara et al 2025
www.cell.com/iscience/ful...
Devastating for scientists and their research, and everyone who benefits from that research.
Iโm not sure if everyone outside academia is aware that a delay or โpauseโ in grant funding often means the researchers themselves are lost from the field, along with their expertise.
Lab Christmas dinner
Celebrating the start of the holiday season with our wonderful lab ๐๐
๐
Grateful for this incredible, fun team - and a great year of science together ๐คฉ๐
Happy holidays!! ๐๐ฅโ๏ธ๐
Jacco came to Lausanne a few months ago and presented this beautiful story from his lab. I love the additional layer of complexity regarding biological cycles in cancer, beyond (now more common) circadian rhythms