How does the nervous system influence cancer ... and vice versa?
Now online @cp-cell.bsky.social our newest review on current and emerging topics in Cancer Neuroscience 🧠, and many new exciting directions ahead.
www.sciencedirect.com/science/arti...
The UK rejoining Erasmus is the best science news for a while! #AcademicSky
www.gov.uk/government/n...
Electromagnetic field-inducible in vivo gene switch for remote spatiotemporal control of gene expression @cellcellpress.bsky.social
www.cell.com/cell/fulltex...
Here are a couple of examples. Lung cancer survival rates for EGFR+ mutated Lung cancer.
It’s well known that inflammation increases cancer risk, but how?
The answer: the epigenome "remembers" inflammation and primes stem cells for cancer.
Here is our paper: nature.com/articles/s41...
And a special shoutout to the lead author
@snaga13.bsky.social
A 🧵
🔬 Watch how cancer and immune cells interact in a living system.
Scientists at BCI have developed mini lab-grown ovarian tumours that recreate the complex neighbourhood of cells in patients. Published today in @natcomms.nature.com.
Read more: bit.ly/4bMCrVg
🧪 #medsky #oncosky @qmul.bsky.social
AP-1 mediates cellular adaptation and memory formation @natcomms.nature.com @pennmedicine.bsky.social
@arjunraj.bsky.social @penngenetics.bsky.social
www.nature.com/articles/s41...
Very happy to see this out. 👏 @yinanwan.bsky.social
Bogdan Bintu and team.
Whole-embryo spatial transcriptomics at subcellular resolution from gastrulation to organogenesis | free link Science www.science.org/eprint/5MHTM...
Humanity is notorious for leaving problems for the next generations, but animals reveal the biology: C. elegans develop germline tumors if THEIR GRAND GRANDPARENTS’ cells fail to clear garbage from their body cavity… What the hell, you ask? Read our new preprint! 👇
www.biorxiv.org/content/10.6...
Portrait shots of two people looking into the camera.
Two Crick group leaders are joining Cancer Grand Challenges teams to tackle big questions in cancer research.
Leanne Li leads a team studying how tumours interact with the nervous system, and Vivian Li joins a @ucl.ac.uk-led team working to rewire cancer cells.
🔗 www.crick.ac.uk/news/2026-03...
@simoncleary.bsky.social, Longhui Qiu, Mark Looney et al. developed a new #intravital technique for imaging pulmonary lymphatics. rupress.org/jem/article/...
📘 In our #Lymphatics collection: rupress.org/jem/collecti...
British Society for Immunology MIG seminar, Dr William Hill, CRUK Manchester Institute: "Signals and Mechanisms of Lung Cancer Promotion by Air Pollutants” Thursday 19th February 12 pm Michael Smith Lecture Theatre Lydia Becker Institute of Immunology and Inflammation
This week, we're joined by @drwilliamhill.bsky.social from @cruk-mi.bsky.social for the next in our @britsocimm.bsky.social MIG Seminar series:
"Signals and Mechanisms of Lung Cancer Promotion by Air Pollutants”
📆 Thursday 19th Feb
🕛 12:00 PM
📍 Michael Smith Lecture Theatre
#ImmunoSky
“Trust in scientists is gone!”
Maria Leptin points to USA, adding:
“To be resilient we must trust that the best researchers know where the scientific frontiers lie and keep diversity in research now for our future. Blue sky science is key to be prepared.”
BMW Foundation
Energy Security Hub
The February issue of Cancer Discovery @aacrjournals.bsky.social is now online! The cover features work by @danielazorin.bsky.social, Dirk Hoffmann, Sophie Heuer, Frank Winkler, et al. on targeting tumor microtubes to disrupt GBM cell networks. Read that & more: aacrjournals.org/cancerdiscov...
Tumor-associated macrophages directly stimulate neurite outgrowth, revealing a dual role in enhancing intratumoral nerve growth and promoting neural repair after severe spinal cord injury @cp-immunity.bsky.social
www.cell.com/immunity/ful...
An in-depth analysis of nutrient availability across mouse tissues reveals their influence on the spread of cancer to other organs @mghsteelelabs.bsky.social @harvardmed.bsky.social @geochurch.bsky.social
www.nature.com/articles/s41... @nature.com
www.nature.com/articles/d41...
Nature research paper: Transient hepatic reconstitution of trophic factors enhances aged immunity
go.nature.com/4pD0f3H
www.cell.com/neuron/fullt... new paper from our group demonstrating how breast tumors dysregulate rhythms in the HPA axis to drive their own growth. Great collaboration with the @corina-amor.bsky.social and @cheadlelab.bsky.social labs @cshlnews.bsky.social
![Comic. Panels up to the 10-year point are grayed out. New panels since the Ten Years comic, which chronicles the first ten years of PERSON 1's journey with cancer: (1) [two people in bed] PERSON 1 (woman): One more chapter? PERSON 2 (man): Don’t we both have to get up early? PERSON 1: Nnnnnggggh PERSON 2: Sure, good point. (2) [many people wearing masks, walking while looking at graphs on their phones] (3) [birds landing on people] PERSON 2 in beanie and scarf: Hah! They like *my* seeds best. PERSON 1 in scarf holding phone with a bird sitting on it: Wait, how do I take a picture of this one? (4) [two people rowing boats with tree landscape] (5) [Person 1 carries overflowing stack of things to Person 2 in bed] PERSON 1: I brought you honey lemon tea, more pillows, a cinnamon roll, Tylenol, another blanket, a– PERSON 2: It was just Appendicitis, I’m really– PERSON 1: *It is my turn to take care of you and I am going to do it right!* (6) [Two people in car] (7) [still in car) PERSON 1: Oh my god. PERSON 2: Oh my god. (8) [car driving] PERSON 1: Pull over! PERSON 2: I am! (9) [both people get out of car] (10) [Large colored panel of aurora borealis over water with both people looking on] (11) [Person 1 sits against tree while Person 2 lies on the ground] PERSON 1: Fifteen years. No sign of the cancer. (12) I *am* having some weird symptoms. Joint pain. Fatigue. I think I’m losing my close-up vision. PERSON 2: Yeah. Me too. (13) PERSON 2: I think we’re getting old. (14) PERSON 1: I guess that’s okay. PERSON 2: It’s all I wanted.](https://cdn.bsky.app/img/feed_thumbnail/plain/did:plc:cz73r7iyiqn26upot4jtjdhk/bafkreihwhjblp5lyiwp63ouar7ocfea7evmckytoeo7rkfuoo4gw5rnrra)
Comic. Panels up to the 10-year point are grayed out. New panels since the Ten Years comic, which chronicles the first ten years of PERSON 1's journey with cancer: (1) [two people in bed] PERSON 1 (woman): One more chapter? PERSON 2 (man): Don’t we both have to get up early? PERSON 1: Nnnnnggggh PERSON 2: Sure, good point. (2) [many people wearing masks, walking while looking at graphs on their phones] (3) [birds landing on people] PERSON 2 in beanie and scarf: Hah! They like *my* seeds best. PERSON 1 in scarf holding phone with a bird sitting on it: Wait, how do I take a picture of this one? (4) [two people rowing boats with tree landscape] (5) [Person 1 carries overflowing stack of things to Person 2 in bed] PERSON 1: I brought you honey lemon tea, more pillows, a cinnamon roll, Tylenol, another blanket, a– PERSON 2: It was just Appendicitis, I’m really– PERSON 1: *It is my turn to take care of you and I am going to do it right!* (6) [Two people in car] (7) [still in car) PERSON 1: Oh my god. PERSON 2: Oh my god. (8) [car driving] PERSON 1: Pull over! PERSON 2: I am! (9) [both people get out of car] (10) [Large colored panel of aurora borealis over water with both people looking on] (11) [Person 1 sits against tree while Person 2 lies on the ground] PERSON 1: Fifteen years. No sign of the cancer. (12) I *am* having some weird symptoms. Joint pain. Fatigue. I think I’m losing my close-up vision. PERSON 2: Yeah. Me too. (13) PERSON 2: I think we’re getting old. (14) PERSON 1: I guess that’s okay. PERSON 2: It’s all I wanted.
Fifteen Years
xkcd.com/3172/
📢 Registration (free!) for the NCI webinar series 'Fueling Cancer Progression by the Nervous System' is open!
🧠🔬 Amongst many excellent speakers, Frank Winkler and @venkatesh-lab.bsky.social discuss #cancerneuroscience of #brainmetastasis
📅 6 exciting topics are covered by leaders in the field 💡!
New preprint 🥳! We made photoclickable HaloTag ligands to precisely control protein labeling on living cells. With it, we can do some cool multicolor stuff. Huge congrats to Franzi and all co-authors! Check it out 👇
www.biorxiv.org/content/10.1...
We're pleased to announce that @charlesswanton.bsky.social is the 2026 winner of the Mike Price Gold Medal Award! The award will be presented at the EACR 2026 Congress in Budapest, where Charles will present the Keynote Award Lecture.
Congratulations 🎉 learn more: magazine.eacr.org/charles-swan...
Longitudinal ultrasensitive ctDNA monitoring for high-resolution lung cancer risk prediction @cellcellpress.bsky.social
www.cell.com/cell/fulltex... @charlesswanton.bsky.social @ucl.ac.uk
We are introducing LipiGo 🤗
A programmable DNA–lipid nanocarrier 🧬 with built-in targeting logic. It de-targets the liver and redirects mRNA delivery into lymphoid organs, enhancing therapies requiring the immune system. Precision delivery at the cell level isn't far! www.biorxiv.org/content/10.1...
Pre-print alert! And this one really is a must read for anyone that does spectral #flowcytometry. It is a complete, fully-automated spectral unmixing pipeline that reduces error up to 9000-fold.
Want to get a tough sample, like lung, looking like this? Read more!
www.biorxiv.org/content/10.1...
🧵1/17
📣Thrilled to share our latest study just out in Cancer Discovery!
➡️
aacrjournals.org/cancerdiscov...
#Circadian #medicine tests if treatment timing can improve patient outcomes. This paper by @mariafelicita.bsky.social @oliviawalch.bsky.social et al considers #chronodiagnostics ...how the outcome of a standard test for glioblastoma differs with time of biopsy. link.springer.com/article/10.1...
Now online in Cancer Discovery @aacrjournals.bsky.social: Screening for Tumor Microtube-Targeting Drugs Identifies PKC Modulators as Multipotent Inhibitors of Glioblastoma Progression - by Daniel Azorín, Dirk Hoffmann, @winklerlab.bsky.social, and colleagues doi.org/10.1158/2159...
